2023
Left ventricular lead implantation failure in an unselected nationwide cohort
Friedman D, Qin L, Freeman J, Singh J, Curtis J, Piccini J, Al-Khatib S, Jackson K. Left ventricular lead implantation failure in an unselected nationwide cohort. Heart Rhythm 2023, 20: 1420-1428. PMID: 37406870, DOI: 10.1016/j.hrthm.2023.06.023.Peer-Reviewed Original ResearchImplant failureIndependent predictorsSleep apneaBlack raceFemale sexQRS durationHispanic ethnicityNational Cardiovascular Data Registry ICD RegistryYounger ageLeft bundle branch blockCoronary sinus dissectionPredictors of LVUnselected nationwide cohortVentricular lead implantationCardiac resynchronization therapy (CRT) proceduresObstructive sleep apneaImplant failure rateSignificant independent predictorsBundle branch blockCoronary sinus accessCRT implantationDiaphragmatic stimulationNationwide cohortEjection fractionICD Registry
2019
Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block
Kawata H, Bao H, Curtis JP, Minges KE, Mitiku T, Birgersdotter-Green U, Feld GK, Hsu JC. Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block. Journal Of The American College Of Cardiology 2019, 73: 3082-3099. PMID: 31221257, DOI: 10.1016/j.jacc.2019.04.025.Peer-Reviewed Original ResearchConceptsNonspecific intraventricular conduction delayRight bundle branch blockCardiac resynchronization therapyCRT-D implantationCRT-eligible patientsBundle branch blockQRS durationHazard ratioBranch blockBetter outcomesCardiac resynchronization defibrillator therapyMultivariable adjusted hazard ratiosAdjusted hazard ratioIntraventricular conduction delayCareful patient selectionEligible patientsDefibrillator therapyMultivariable adjustmentResynchronization therapyClinical outcomesPatient selectionConduction abnormalitiesRegistry dataConduction delayPatients
2017
Coronary Venous Dissection from Left Ventricular Lead Placement During Cardiac Resynchronization Therapy With Defibrillator Implantation and Associated in-Hospital Adverse Events (from the NCDR ICD Registry)
Hsu JC, Varosy PD, Bao H, Dewland TA, Curtis JP, Marcus GM. Coronary Venous Dissection from Left Ventricular Lead Placement During Cardiac Resynchronization Therapy With Defibrillator Implantation and Associated in-Hospital Adverse Events (from the NCDR ICD Registry). The American Journal Of Cardiology 2017, 121: 55-61. PMID: 29102348, DOI: 10.1016/j.amjcard.2017.09.019.Peer-Reviewed Original ResearchConceptsCRT-D recipientsVentricular lead placementHospital adverse eventsVenous dissectionMultivariable adjustmentAdverse eventsMajor complicationsLead placementGreater oddsPrevious coronary artery bypass graftImplantable Cardioverter-Defibrillator RegistryLeft ventricular lead placementCoronary artery bypass graftHierarchical multivariable logistic regressionHospital clinical outcomesArtery bypass graftCardiac resynchronization therapyMultivariable logistic regressionBundle branch blockHospital complicationsHospital mortalityHospital deathHospital stayDefibrillator implantationProlonged hospitalization
2015
Cardiac Resynchronization Therapy in Women Versus Men
Zusterzeel R, Spatz ES, Curtis JP, Sanders WE, Selzman KA, Piña IL, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Caños DA, Strauss DG. Cardiac Resynchronization Therapy in Women Versus Men. Circulation Cardiovascular Quality And Outcomes 2015, 8: s4-s11. PMID: 25714821, DOI: 10.1161/circoutcomes.114.001548.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesDefibrillators, ImplantableElectric CountershockFemaleHealth Status DisparitiesHeart Conduction SystemHeart FailureHumansKaplan-Meier EstimateMalePropensity ScoreProportional Hazards ModelsRegistriesRisk FactorsSex FactorsStroke VolumeTreatment OutcomeUnited StatesVentricular Function, LeftConceptsLeft bundle branch blockQRS durationImplantable cardioverter defibrillatorPatient sexDeath riskCardioverter defibrillatorBetter survivalMortality differencesNew York Heart Association class IIILeft ventricular ejection fractionWomen Versus MenCardiac resynchronization therapyVentricular ejection fractionRelative death riskBenefit of CRTLonger QRS durationShorter QRS durationBundle branch blockLower mortality riskEjection fractionHeart failureResynchronization therapyCardiac resynchronizationBranch blockMortality risk
2014
Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR
Zusterzeel R, Curtis JP, Caños DA, Sanders WE, Selzman KA, Piña IL, Spatz ES, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Strauss DG. Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR. Journal Of The American College Of Cardiology 2014, 64: 887-894. PMID: 25169173, DOI: 10.1016/j.jacc.2014.06.1162.Peer-Reviewed Original ResearchConceptsLeft bundle branch blockNational Cardiovascular Data RegistryLonger QRS durationQRS durationQRS morphologyHazard ratioMortality riskBetter survivalCardiac resynchronization therapy defibrillator implantationImplantable Cardioverter-Defibrillator RegistrySex-specific mortality risksCRT-D implantationCRT-D patientsBundle branch blockLower mortality riskSex differencesComparator groupBranch blockData registryBetter outcomesPatientsLower mortalitySurvival curvesMortalityWomenComparative effectiveness of cardiac resynchronization therapy with an implantable cardioverter-defibrillator versus defibrillator therapy alone: a cohort study.
Masoudi FA, Mi X, Curtis LH, Peterson PN, Curtis JP, Fonarow GC, Hammill SC, Heidenreich PA, Al-Khatib SM, Piccini JP, Qualls LG, Hernandez AF. Comparative effectiveness of cardiac resynchronization therapy with an implantable cardioverter-defibrillator versus defibrillator therapy alone: a cohort study. Annals Of Internal Medicine 2014, 160: 603-11. PMID: 24798523, DOI: 10.7326/m13-1879.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac Resynchronization TherapyComparative Effectiveness ResearchDefibrillators, ImplantableElectrocardiographyHeart FailureHumansInfectionsPatient ReadmissionPropensity ScoreRetrospective StudiesRisk FactorsStroke VolumeTreatment OutcomeVentricular Dysfunction, LeftConceptsReduced left ventricular ejection fractionLeft ventricular ejection fractionHeart failure readmissionVentricular ejection fractionCardiac resynchronization therapyICD therapyQRS durationLower riskCohort studyICD RegistryResynchronization therapyEjection fractionNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator therapyLeft bundle branch blockPropensity-matched patientsRetrospective cohort studyCardioverter-defibrillator therapyDevice-related complicationsBundle branch blockDevice-related infectionsCardiovascular readmissionCause readmissionDefibrillator therapyICD implantation
2013
Cardiac Perforation From Implantable Cardioverter-Defibrillator Lead Placement
Hsu JC, Varosy PD, Bao H, Dewland TA, Curtis JP, Marcus GM. Cardiac Perforation From Implantable Cardioverter-Defibrillator Lead Placement. Circulation Cardiovascular Quality And Outcomes 2013, 6: 582-590. PMID: 24002030, DOI: 10.1161/circoutcomes.113.000299.Peer-Reviewed Original ResearchConceptsPredictors of perforationCardiac perforationICD recipientsMajor complicationsGreater oddsImplantable cardioverter defibrillator lead placementHigher left ventricular ejection fractionFirst-time ICD recipientsLeft ventricular ejection fractionHierarchical multivariable logistic regressionHeart failure classICD lead implantationAssociated adverse eventsVentricular ejection fractionMultivariable logistic regressionLength of stayBundle branch blockCardiac bypass surgeryHospital mortalityHospital deathHospital stayBypass surgeryFeared complicationMultivariable adjustmentAdverse eventsQRS Duration, Bundle-Branch Block Morphology, and Outcomes Among Older Patients With Heart Failure Receiving Cardiac Resynchronization Therapy
Peterson PN, Greiner MA, Qualls LG, Al-Khatib SM, Curtis JP, Fonarow GC, Hammill SC, Heidenreich PA, Hammill BG, Piccini JP, Hernandez AF, Curtis LH, Masoudi FA. QRS Duration, Bundle-Branch Block Morphology, and Outcomes Among Older Patients With Heart Failure Receiving Cardiac Resynchronization Therapy. JAMA 2013, 310: 617-626. PMID: 23942680, DOI: 10.1001/jama.2013.8641.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesCardiovascular DiseasesCohort StudiesElectrocardiographyFee-for-Service PlansFemaleHeart FailureHumansMaleMedicarePatient ReadmissionRetrospective StudiesRiskTreatment OutcomeUnited StatesConceptsLeft bundle branch blockCRT-D implantationCardiac resynchronization therapyHeart failure readmissionQRS durationCause mortalityICD RegistryResynchronization therapyUnadjusted ratesMedicare beneficiariesNational Cardiovascular Data Registry ICD RegistryClinical practiceBundle branch block morphologyCause readmission rateRetrospective cohort studyLonger QRS durationBundle branch blockService Medicare beneficiariesCause readmissionCohort studyCRT-defibrillatorOlder patientsReadmission ratesHeart failureClinical trials
2006
The Pre-Hospital Electrocardiogram and Time to Reperfusion in Patients With Acute Myocardial Infarction, 2000–2002 Findings From the National Registry of Myocardial Infarction-4
Curtis JP, Portnay EL, Wang Y, McNamara RL, Herrin J, Bradley EH, Magid DJ, Blaney ME, Canto JG, Krumholz HM. The Pre-Hospital Electrocardiogram and Time to Reperfusion in Patients With Acute Myocardial Infarction, 2000–2002 Findings From the National Registry of Myocardial Infarction-4. Journal Of The American College Of Cardiology 2006, 47: 1544-1552. PMID: 16630989, DOI: 10.1016/j.jacc.2005.10.077.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPre-hospital electrocardiogramPrimary percutaneous coronary interventionMyocardial infarction 4Mean doorReperfusion timeHospital characteristicsNational registryTreatment of STEMILimited contemporary informationElevation myocardial infarctionPercutaneous coronary interventionBundle branch blockAcute reperfusionECG usePCI cohortReperfusion therapyBalloon timeCoronary interventionFibrinolytic therapyTherapy cohortMyocardial infarctionBranch blockNational guidelinesDrug time