Featured Publications
Identifying high-value care for Medicare beneficiaries: a cross-sectional study of acute care hospitals in the USA
Herrin J, Yu H, Venkatesh AK, Desai SM, Thiel CL, Lin Z, Bernheim SM, Horwitz LI. Identifying high-value care for Medicare beneficiaries: a cross-sectional study of acute care hospitals in the USA. BMJ Open 2022, 12: e053629. PMID: 35361641, PMCID: PMC8971780, DOI: 10.1136/bmjopen-2021-053629.Peer-Reviewed Original ResearchConceptsAcute care hospitalsHigh-value careStar hospitalsCare hospitalMedicare spendingEligible Medicare patientsRetrospective observational studyCross-sectional studyNon-teaching statusHigh-quality careHigh-quality hospitalsLow-cost hospitalsHigh-cost hospitalsCharacteristics of hospitalsValue of careSecondary outcomesPrimary outcomeMedicare patientsObservational studyMedicare beneficiariesHospitalQuality careOverall star ratingHospital Value
2024
Primary outcomes of the enhanced, EHR-facilitated cancer symptom control (E2C2) cluster-randomized, stepped wedge, pragmatic trial.
Cheville A, Pachman D, Kroenke K, Herrin J, Grzegorczyk V, Mitchell S, Griffin J, Ridgeway J, Austin J, Smith A, Chlan L, Tofthagen C, Ruddy K. Primary outcomes of the enhanced, EHR-facilitated cancer symptom control (E2C2) cluster-randomized, stepped wedge, pragmatic trial. Journal Of Clinical Oncology 2024, 42: lba12006-lba12006. DOI: 10.1200/jco.2024.42.17_suppl.lba12006.Peer-Reviewed Original ResearchElectronic patient-reported outcome measuresCollaborative care modelElectronic health recordsNumerical rating scaleCluster-randomizedPragmatic trialSymptom burdenAssociated with adverse health outcomesCCM-based interventionsPatient-reported outcome measuresHealth service outcomesSelf-management informationClinician decision supportPrimary outcomeCancer type or stageMulti-state health systemCancer symptom controlCluster randomized trialMedical oncology clinicAdverse health outcomesUsual careCare modelCare teamSymptom managementSymptom scoresCalculation of Overall Hospital Quality Star Ratings With and Without Inclusion of the Peer Grouping Step
Gettel C, Bagshaw K, Qin L, Lin Z, Rothenberg E, Omotosho P, Goutos D, Herrin J, Suter L, Schreiber M, Fleisher L, Myers R, Spivack S, Venkatesh A. Calculation of Overall Hospital Quality Star Ratings With and Without Inclusion of the Peer Grouping Step. JAMA Network Open 2024, 7: e2411933. PMID: 38753326, PMCID: PMC11099678, DOI: 10.1001/jamanetworkopen.2024.11933.Peer-Reviewed Original ResearchConceptsCenters for Medicare & Medicaid ServicesCross-sectional studyHospital characteristicsHigher star ratingsStar ratingsOverall hospital qualityLowest-performing hospitalsOverall star ratingQuality star ratingsHospital star ratingsStar Ratings scoresHospital qualityHospital performanceStratified hospitalsMedicaid ServicesMain OutcomesFace validityPeer groupPeer group approachPrimary outcomePeer comparisonHospitalRating scoresPeerMeasurement group
2019
Associations between community well-being and hospitalisation rates: results from a cross-sectional study within six US states
Roy B, Riley C, Herrin J, Spatz E, Hamar B, Kell KP, Rula EY, Krumholz H. Associations between community well-being and hospitalisation rates: results from a cross-sectional study within six US states. BMJ Open 2019, 9: e030017. PMID: 31780588, PMCID: PMC6886944, DOI: 10.1136/bmjopen-2019-030017.Peer-Reviewed Original ResearchConceptsHospitalisation ratesZip codesPrimary care physician densityCross-sectional study SETTINGCancer-related admissionsRespiratory-related admissionsCross-sectional studyQuality of lifeRace/ethnicityCause hospitalisationSecondary outcomesPrimary outcomeHighest quintileUnnecessary hospitalisationAdmission ratesSD increaseHospitalisationLife benefitsPhysician densityStudy settingMain independent variableBeing IndexHospital bedsAdmissionGallup-Sharecare WellHome Health Care After Skilled Nursing Facility Discharge Following Heart Failure Hospitalization
Weerahandi H, Bao H, Herrin J, Dharmarajan K, Ross JS, Jones S, Horwitz LI. Home Health Care After Skilled Nursing Facility Discharge Following Heart Failure Hospitalization. Journal Of The American Geriatrics Society 2019, 68: 96-102. PMID: 31603248, PMCID: PMC6964248, DOI: 10.1111/jgs.16179.Peer-Reviewed Original ResearchConceptsSkilled nursing facilitiesHF hospitalizationReadmission ratesReadmission riskHeart failure readmission ratesDays of dischargeHeart failure hospitalizationRetrospective cohort studyHospital discharge practicesMore functional impairmentHome health careFailure hospitalizationHF patientsUnplanned readmissionCohort studyHospital dischargePrimary outcomeRestorative therapySNF stayFunctional impairmentHome healthcare servicesService Medicare dataAdjusted modelCox modelNursing facilities
2018
Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma
Hess EP, Homme JL, Kharbanda AB, Tzimenatos L, Louie JP, Cohen DM, Nigrovic LE, Westphal JJ, Shah ND, Inselman J, Ferrara MJ, Herrin J, Montori VM, Kuppermann N. Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma. JAMA Network Open 2018, 1: e182430. PMID: 30646167, PMCID: PMC6324506, DOI: 10.1001/jamanetworkopen.2018.2430.Peer-Reviewed Original ResearchConceptsMinor head traumaIntermediate riskHead traumaParents of childrenComputed tomographyDecisional conflictUsual careEmergency departmentImportant traumatic brain injuryCT ratesDecision aid armPatients' mean ageUsual care armUS emergency departmentsHealth care utilizationAvailable diagnostic optionsTraumatic brain injuryDecision aidChildren ages 2Care armSecondary outcomesPrimary outcomeCare utilizationNonwhite raceEligible participantsEvaluating the impact of multilevel evidence-based implementation strategies to enhance provider recommendation on human papillomavirus vaccination rates among an empaneled primary care patient population: a study protocol for a stepped-wedge cluster randomized trial
Finney Rutten LJ, Radecki Breitkopf C, St. Sauver JL, Croghan IT, Jacobson DJ, Wilson PM, Herrin J, Jacobson RM. Evaluating the impact of multilevel evidence-based implementation strategies to enhance provider recommendation on human papillomavirus vaccination rates among an empaneled primary care patient population: a study protocol for a stepped-wedge cluster randomized trial. Implementation Science 2018, 13: 96. PMID: 30001723, PMCID: PMC6043954, DOI: 10.1186/s13012-018-0778-x.Peer-Reviewed Original ResearchConceptsHPV vaccination ratesEvidence-based implementation strategiesStepped-wedge clusterVaccination ratesIntervention 1Human papillomavirusIntervention 2Human papillomavirus (HPV) vaccination ratesPrimary care patient populationPrimary care sitesProvider-level interventionsPractice-level interventionProcess evaluationAdolescent vaccinesBackgroundEach yearHPV vaccineMale patientsPrimary outcomePediatric populationPatient numbersPatient populationProvider recommendationStudy protocolClinical trialsBlock randomization
2016
Shared decision making in patients with low risk chest pain: prospective randomized pragmatic trial
Hess EP, Hollander JE, Schaffer JT, Kline JA, Torres CA, Diercks DB, Jones R, Owen KP, Meisel ZF, Demers M, Leblanc A, Shah ND, Inselman J, Herrin J, Castaneda-Guarderas A, Montori VM. Shared decision making in patients with low risk chest pain: prospective randomized pragmatic trial. The BMJ 2016, 355: i6165. PMID: 27919865, PMCID: PMC5152707, DOI: 10.1136/bmj.i6165.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAdultAftercareAmbulatory CareAttitude of Health PersonnelChest PainChoice BehaviorConflict, PsychologicalDecision MakingDecision Support TechniquesEmergency Service, HospitalFemaleHealth Knowledge, Attitudes, PracticeHospital UnitsHospitalizationHumansMaleMiddle AgedMyocardial InfarctionObservationPatient Acceptance of Health CarePatient ParticipationPatient SatisfactionRisk AssessmentTrustConceptsAcute coronary syndromeMajor adverse cardiac eventsAdverse cardiac eventsCardiac testingCoronary syndromeChest painUsual careCardiac eventsPatient knowledgeLow-risk chest painPossible acute coronary syndromeDecision aid armFurther cardiac testingRandomized pragmatic trialRisk chest painUsual care armObservation unitProportion of patientsRate of admissionCare armSecondary outcomesPrimary outcomePrimary complaintTRIAL REGISTRATIONEmergency clinicians
2015
Long-term Outcomes After Stepping Down Asthma Controller Medications A Claims-Based, Time-to-Event Analysis
Rank MA, Johnson R, Branda M, Herrin J, van Houten H, Gionfriddo MR, Shah ND. Long-term Outcomes After Stepping Down Asthma Controller Medications A Claims-Based, Time-to-Event Analysis. CHEST Journal 2015, 148: 630-639. PMID: 25997080, PMCID: PMC4556120, DOI: 10.1378/chest.15-0301.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAgedAged, 80 and overAnti-Asthmatic AgentsAsthmaComorbidityDrug Administration ScheduleEmergency Service, HospitalFemaleHospitalizationHumansInsurance Claim ReviewMaleMedicare Part CMedication AdherenceRecurrenceRetrospective StudiesRisk FactorsTreatment OutcomeUnited StatesConceptsAsthma controller medicationsAsthma exacerbationsLong-term outcomesController medicationsAsthma stabilityAsthma medicationsHealth-care provider guidanceFirst asthma exacerbationED visitsPrimary outcomeAdherence lapsesMedicationsExacerbationFour-month intervalsProvider guidanceStudy settingEvent analysisRetrospective timeMonthsAsthmaOutcomesIndividualsHospitalizationPeriodMonth stability
2014
Impact of an EHR-Based Diabetes Management Form on Quality and Outcomes of Diabetes Care in Primary Care Practices
Herrin J, da Graca B, Aponte P, Stanek HG, Cowling T, Fullerton C, Hollander P, Ballard DJ. Impact of an EHR-Based Diabetes Management Form on Quality and Outcomes of Diabetes Care in Primary Care Practices. American Journal Of Medical Quality 2014, 30: 14-22. PMID: 24399633, DOI: 10.1177/1062860613516991.Peer-Reviewed Original ResearchConceptsPrimary care practicesAspirin prescriptionBlood pressureOptimal careCare practicesLow-density lipoprotein cholesterolChronic disease careDelivery of careElectronic health recordsDMF useFoot examsInsulin useLipoprotein cholesterolPrimary outcomeLDL cholesterolDisease careDiabetes careDiabetes patientsEvidence-based targetsHealth information technologyMicroalbumin testNumber of visitsLess improvementPatientsCare
2012
The Effectiveness of Implementing an Electronic Health Record on Diabetes Care and Outcomes
Herrin J, da Graca B, Nicewander D, Fullerton C, Aponte P, Stanek G, Cowling T, Collinsworth A, Fleming NS, Ballard DJ. The Effectiveness of Implementing an Electronic Health Record on Diabetes Care and Outcomes. Health Services Research 2012, 47: 1522-1540. PMID: 22250953, PMCID: PMC3401397, DOI: 10.1111/j.1475-6773.2011.01370.x.Peer-Reviewed Original ResearchConceptsPrimary care practicesBlood pressureDiabetes careOptimal careCare practicesDiastolic blood pressureSystolic blood pressureYears of ageElectronic health record implementationElectronic health recordsAspirin prescriptionUnexposed patientsAspirin useCare bundleInsulin usePatient ageLipid controlPrimary outcomeClinical outcomesLDL cholesterolSmoking cessationChart auditDiabetes measuresDiabetes patientsPatients
2011
Framing of health information messages
Akl EA, Oxman AD, Herrin J, Vist GE, Terrenato I, Sperati F, Costiniuk C, Blank D, Schünemann H. Framing of health information messages. 2011, cd006777. PMID: 22161408, DOI: 10.1002/14651858.cd006777.pub2.Peer-Reviewed Original ResearchConceptsStandardized mean differenceHealth professionalsPre-planned subgroup analysisScreening testCochrane Central RegisterModerate-quality evidenceRelated systematic reviewsCross-over studyQuality of evidenceHealth information messagesChance of mortalityCentral RegisterGRADE approachControlled TrialsPrimary outcomeReview authorsDATA COLLECTIONAdverse outcomesLanguage restrictionsQuality evidenceSubgroup analysisReference listsSystematic reviewChances of survivalMean difference
2005
A Randomized Outpatient Trial of a Decision-Support Information Technology Tool
Apkon M, Mattera JA, Lin Z, Herrin J, Bradley EH, Carbone M, Holmboe ES, Gross CP, Selter JG, Rich AS, Krumholz HM. A Randomized Outpatient Trial of a Decision-Support Information Technology Tool. JAMA Internal Medicine 2005, 165: 2388-2394. PMID: 16287768, DOI: 10.1001/archinte.165.20.2388.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAttitude of Health PersonnelCost-Benefit AnalysisDecision Support Systems, ClinicalFemaleFloridaHealth ResourcesHospitals, MilitaryHumansKentuckyMaleMass ScreeningMultivariate AnalysisOutcome and Process Assessment, Health CarePatient SatisfactionPreventive MedicineQuality of Health CareConceptsProvider satisfactionAmbulatory clinic visitsUsual care patientsDays of enrollmentQuality process measuresQuality of careProportion of opportunitiesUsual careClinic visitsOutpatient trialSecondary outcomesPrimary outcomeAcute carePatient satisfactionIntervention groupHealth care opportunitiesPatientsClinical decisionCare opportunitiesPharmacy resourcesPreventive measuresProcess measuresCareMedical resourcesModest improvementPhysician specialty and mortality among elderly patients hospitalized with heart failure
Foody JM, Rathore SS, Wang Y, Herrin J, Masoudi FA, Havranek EP, Krumholz HM. Physician specialty and mortality among elderly patients hospitalized with heart failure. The American Journal Of Medicine 2005, 118: 1120-1125. PMID: 16194643, DOI: 10.1016/j.amjmed.2005.01.075.Peer-Reviewed Original ResearchConceptsHeart failureFamily physiciansGeneral physiciansSpecialty careDay of admissionCause mortalityCardiology consultationElderly patientsPrimary outcomePhysician specialtyMedicare beneficiariesMortality ratePatientsCardiologistsPhysiciansMortalityInternistsCareOutcomesConsultationFailureDaysSpecialtiesAdmissionTimes to Treatment in Transfer Patients Undergoing Primary Percutaneous Coronary Intervention in the United States
Nallamothu BK, Bates ER, Herrin J, Wang Y, Bradley EH, Krumholz HM. Times to Treatment in Transfer Patients Undergoing Primary Percutaneous Coronary Intervention in the United States. Circulation 2005, 111: 761-767. PMID: 15699253, DOI: 10.1161/01.cir.0000155258.44268.f8.Peer-Reviewed Original ResearchConceptsPrimary PCIPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionPercutaneous coronary interventionBalloon timeTransfer patientsCoronary interventionInterhospital transferMyocardial infarctionTotal doorRecent clinical trialsSpecific ECG findingsMultivariable hierarchical modelsChest painHospital presentationInitial hospitalFibrinolytic therapyPCI hospitalsPrimary outcomeSymptom onsetComorbid conditionsTreatment delayECG findingsHospital characteristicsNational registry