2021
Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury
Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar MJ, Taylor SR, Winkler EA, Deng H, McCrea M, Stein MB, Robertson CS, Levin HS, Dikmen S, Temkin NR, Barber J, Giacino JT, Mukherjee P, Wang KKW, Okonkwo DO, Markowitz AJ, Jain S, Lowenstein D, Manley GT, Diaz-Arrastia R, , Badjatia N, Duhaime AC, Feeser VR, Gaudette E, Gopinath S, Keene CD, Korley FK, Madden C, Merchant R, Schnyer D, Zafonte R. Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury. JAMA Network Open 2021, 4: e2140191. PMID: 34964854, PMCID: PMC8717106, DOI: 10.1001/jamanetworkopen.2021.40191.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryGlasgow Coma Scale scorePosttraumatic epilepsyBrief Symptom Inventory-18Positive screening resultsCohort studyBrain injuryScreening resultsGlasgow Outcome Scale Extended scoreScale scoreInitial Glasgow Coma Scale scoreGlasgow Outcome Scale-ExtendedTraumatic Brain Injury (CENTER-TBI) studyProspective cohort studyLong-term outcomesUS trauma centersNegative screening resultsTBI common data elementsBrain Injury StudyHigher BSI scoresAntiepileptogenic therapiesPrimary outcomeTBI cohortIdentified patientsTrauma center
2020
Association of race and ethnicity to incident epilepsy, or epileptogenesis, after subdural hematoma.
Brown SC, King ZA, Kuohn L, Kamel H, Gilmore EJ, Frontera JA, Murthy S, Kim JA, Omay SB, Falcone GJ, Sheth KN. Association of race and ethnicity to incident epilepsy, or epileptogenesis, after subdural hematoma. Neurology 2020, 95: e2890-e2899. PMID: 32907969, PMCID: PMC7734738, DOI: 10.1212/wnl.0000000000010742.Peer-Reviewed Original ResearchConceptsSubdural hematomaEmergency departmentMultivariable Cox regressionRetrospective cohort studyMedical risk factorsDevelopment of epilepsyNontraumatic subdural hematomaAssociation of raceDiagnosis of epilepsyCohort studyPrimary outcomeRenal diseaseStatus epilepticusWhite patientsBlack patientsHospital revisitsCox regressionBlack raceDiagnosis codesRisk factorsClaims dataInjury severityEpilepsyDrug useSurvival analysis