2022
Epileptiform activity predicts epileptogenesis in cerebral hemorrhage
Kong THJ, Azeem M, Naeem A, Allen S, Kim JA, Struck AF. Epileptiform activity predicts epileptogenesis in cerebral hemorrhage. Annals Of Clinical And Translational Neurology 2022, 9: 1475-1480. PMID: 36030385, PMCID: PMC9463945, DOI: 10.1002/acn3.51637.Peer-Reviewed Original ResearchConceptsEpileptiform activitySubarachnoid hemorrhageRisk factorsRetrospective case-control studyNontraumatic intraparenchymal hemorrhagesDevelopment of epilepsyCase-control studyS scoresClinical seizuresAcute phaseCerebral hemorrhageIntraparenchymal hemorrhageHemorrhageSeizuresEpilepsyScoresEpileptogenesisPatientsActivityIntraparenchymal
2021
A model of metabolic supply-demand mismatch leading to secondary brain injury
Song JL, Kim JA, Struck AF, Zhang R, Westover MB. A model of metabolic supply-demand mismatch leading to secondary brain injury. Journal Of Neurophysiology 2021, 126: 653-667. PMID: 34232754, PMCID: PMC8815783, DOI: 10.1152/jn.00674.2020.Peer-Reviewed Original ResearchConceptsPrimary brain injurySecondary brain injuryAcute brain injuryBrain injuryExtracellular potassiumAdditional brain injuryAssociation of seizuresIschemic strokeNeurologic insultPreventable complicationsSeizure activityCommon sequalaeTissue hypoxiaMetabolic crisisSeizuresInjuryExcitotoxicityPatientsCommon associationAssociationCurrent practiceExcitotoxityComplicationsHemorrhageIschemia
2020
Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury
Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA. Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury. Current Neurology And Neuroscience Reports 2020, 20: 42. PMID: 32715371, PMCID: PMC9353690, DOI: 10.1007/s11910-020-01060-4.Peer-Reviewed Original ResearchConceptsIctal-interictal continuumBrain injuryAcute brain injuryBetter clinical outcomesTraumatic brain injuryRecent FindingsCurrent literatureIncreased morbidityClinical outcomesEpileptiform abnormalitiesEEG findingsMortality riskEEG monitoringEpileptiform patternsPrognostic modelSeizuresClinical settingInjuryLogistical barriersElectroencephalogram studyUse of EEGABIPractical barriersEEG analysisEEGMorbidity