Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects
Arout CA, Perrino AC, Ralevski E, Acampora G, Koretski J, Limoncelli D, Newcomb J, Petrakis IL. Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects. Alcohol Clinical And Experimental Research 2016, 40: 1425-1429. PMID: 27218476, PMCID: PMC4930397, DOI: 10.1111/acer.13095.Peer-Reviewed Original ResearchConceptsCapsaicin-induced hyperalgesiaVon Frey techniqueTime pointsArea of hyperalgesiaIntradermal capsaicin injectionExperimental pain paradigmVisual analog scaleAdditional outcome measuresImportant clinical implicationsTest dayETOH infusionHyperalgesia areasIntravenous EtOHAntihyperalgesic effectCentral sensitizationPrimary outcomeCapsaicin injectionChronic painPain processingAnalog scaleBreath alcohol concentrationIntravenous ethanolPain medicineHyperalgesiaOutcome measures