Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry
Horowitz J, Jaber W, Stegman B, Rosenberg M, Fanola C, Bhat A, Gondi S, Castle J, Ahmed M, Brown M, Amin R, Bisharat M, Butros P, DuCoffe A, Savin M, Pollak J, Weinberg M, Brancheau D, Toma C, Investigators F. Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 3: 101124. PMID: 39131977, PMCID: PMC11307390, DOI: 10.1016/j.jscai.2023.101124.Peer-Reviewed Original ResearchHigh-risk pulmonary embolismMajor adverse eventsPulmonary embolismMechanical thrombectomyAdverse eventsUS cohortProcedure-related adverse eventsAcute mortalityDepressed cardiac indexDevice-related mortalityRisk pulmonary embolismSubset of patientsSystolic blood pressureFurther prospective dataMin/m2Intensive care unitElevated lactate levelsComers registryFlowTriever SystemMajor bleedingCardiac indexCardiology guidelinesAcute outcomesBlood pressureCare unitAcute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism.
Toma C, Jaber W, Weinberg M, Bunte M, Khandhar S, Stegman B, Gondi S, Chambers J, Amin R, Leung D, Kado H, Brown M, Sarosi M, Bhat A, Castle J, Savin M, Siskin G, Rosenberg M, Fanola C, Horowitz J, Pollak J. Acute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism. EuroIntervention 2023, 18: 1201-1212. PMID: 36349702, PMCID: PMC9936254, DOI: 10.4244/eij-d-22-00732.Peer-Reviewed Original ResearchConceptsHigh-risk PEDevice-related deathsPulmonary artery pressureMajor adverse eventsAdverse eventsMechanical thrombectomyFlowTriever SystemArtery pressureUS cohortLarge real-world populationMean pulmonary artery pressureImmediate haemodynamic improvementIntraprocedural adverse eventsPrimary safety endpointRight ventricle/Favorable safety profileIntensive care unitPulmonary embolism treatmentReal-world populationDyspnoea improvementHaemodynamic improvementMajor bleedingRisk PECardiac indexCause mortality