Antigen Density Impacts RBC Survival and Antigen Modulation Following Incompatible RBC Transfusion
Yoo J, Arthur C, Zerra P, Girard-Pierce K, Hendrickson J, Stowell S. Antigen Density Impacts RBC Survival and Antigen Modulation Following Incompatible RBC Transfusion. Blood 2015, 126: 2350. DOI: 10.1182/blood.v126.23.2350.2350.Peer-Reviewed Original ResearchIncompatible RBC transfusionHemolytic transfusion reactionsWild-type C57BL/6 miceRBC transfusionIncompatible transfusionsAntigen densityAntigen modulationFlow cytometric analysisKEL antigenRBC survivalKEL RBCsImmunized recipientsAntigen levelsCytometric analysisFatal hemolytic transfusion reactionRecipient WT miceChronic transfusion therapyTransfusion of RBCsNon-immunized miceLow antigen densityAntibody-mediated removalAlloimmunized individualsAdverse eventsDonor antigensPost transfusion