Berkeley Mice with Sickle Cell Disease Are Not More Immunizable to Transfused HOD Red Blood Cells Than Sickle Trait Control Mice
HendricKson J, Archer D, Perry J, Hillyer C, Zimring J. Berkeley Mice with Sickle Cell Disease Are Not More Immunizable to Transfused HOD Red Blood Cells Than Sickle Trait Control Mice. Blood 2008, 112: 292. DOI: 10.1182/blood.v112.11.292.292.Peer-Reviewed Original ResearchCo-stimulatory molecule expressionSickle cell diseaseBerkeley miceAntigen presenting cellsCell diseaseSickle cell traitMolecule expressionForeign antigensRBC alloimmunizationBaseline inflammationDendritic cellsPresenting cellsRed blood cell alloimmunizationCell traitIndividual miceELISA 2 weeksRate of alloimmunizationRBC-specific expressionTransfusion of RBCsHuman blood group antigensLevel of illnessAntigen hen egg lysozymeDonor/recipientHigh rateTime of illness