2020
A potential association of an interferon gene signature with RBC alloimmunization in sickle cell disease
Madany E, Kadi N, Pandya S, Hendrickson J, Gibb D. A potential association of an interferon gene signature with RBC alloimmunization in sickle cell disease. The Journal Of Immunology 2020, 204: 145.18-145.18. DOI: 10.4049/jimmunol.204.supp.145.18.Peer-Reviewed Original ResearchSickle cell diseaseInterferon-stimulated genesRBC alloimmunizationMore alloantibodiesGene signatureSCD patientsCell diseaseFrequency of alloimmunizationChronic inflammatory stateInterferon gene signatureProduction of alloantibodiesMultiple interferon-stimulated genesType 1 interferonMyxovirus resistance protein 1Resistance protein 1Alloimmunization frequencyCompatible RBCsRBC transfusionInflammatory stateMxA expressionDisease populationTransfusion modelAlloimmunizationPatientsSiglec-1
2013
Transfusion Of RBCs With Low-Density KEL Induces Tolerance To The KEL Antigen
Stowell S, Arthur C, Smith N, Girard-Pierce K, Zimring J, Hendrickson J. Transfusion Of RBCs With Low-Density KEL Induces Tolerance To The KEL Antigen. Blood 2013, 122: 1160. DOI: 10.1182/blood.v122.21.1160.1160.Peer-Reviewed Original ResearchKEL RBCsRBC transfusionAntibody formationKEL antigenDetectable IgMRBC alloimmunizationWestern blot analysisC57BL/6 recipientsAntigen densityDay 3RBC antigensDays post transfusionTransfusion of RBCsSubsequent responseBlot analysisFlow cytometric analysisAnalysis of serumCompatible RBCsRBC alloantigensRepeat transfusionPost transfusionAntigen levelsImmunological outcomesRBC exposureSpecific alloantibodies