2009
Localized transmeningeal muscimol prevents neocortical seizures in rats and nonhuman primates: Therapeutic implications
Ludvig N, Baptiste SL, Tang HM, Medveczky G, Von Gizycki H, Charchaflieh J, Devinsky O, Kuzniecky RI. Localized transmeningeal muscimol prevents neocortical seizures in rats and nonhuman primates: Therapeutic implications. Epilepsia 2009, 50: 678-693. PMID: 19055494, DOI: 10.1111/j.1528-1167.2008.01914.x.Peer-Reviewed Original ResearchConceptsMuscimol pretreatmentNeocortical seizuresEEG seizuresAdjacent EEG electrodesFocal neocortical seizuresEffects of AChIntractable focal epilepsySimilar deliveryBehavior of ratsSeizure activityFocal epilepsyAdditional ratsTherapeutic implicationsSubarachnoid spaceMuscimolSeizuresEEG power spectraParietal cortexRatsSquirrel monkeysAChElectroencephalography (EEG) activityMonkeysLast groupACSF
1998
The Effect of Fentanyl on Electrophysiologic Recovery of CA 1 Pyramidal Cells from Anoxia in the Rat Hippocampal Slice
Charchaflieh J, Cottrell J, Kass I. The Effect of Fentanyl on Electrophysiologic Recovery of CA 1 Pyramidal Cells from Anoxia in the Rat Hippocampal Slice. Anesthesia & Analgesia 1998, 87: 68-71.. DOI: 10.1213/00000539-199807000-00015.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidAnesthetics, IntravenousAnimalsCell HypoxiaDose-Response Relationship, DrugElectrophysiologyFentanylMaleNeuronsPyramidal CellsRatsRats, Sprague-DawleyConceptsEffects of fentanylCA 1 pyramidal cellsMin of anoxiaAnoxic injuryControl groupHippocampal slicesPyramidal cellsRat hippocampal slice modelRat hippocampal slicesAdult Sprague-DawleyHippocampal slice modelSchaffer collateral pathwayRat hippocampal neuronsPreanoxic levelElectrophysiologic recoveryAnoxic insultCollateral pathwaysOpioid receptorsPostsynaptic populationRat hippocampusSuch injuriesSprague-DawleyHippocampal neuronsSurgical proceduresFentanylThe effect of fentanyl on electrophysiologic recovery of CA 1 pyramidal cells from anoxia in the rat hippocampal slice.
Charchaflieh J, Cottrell J, Kass I. The effect of fentanyl on electrophysiologic recovery of CA 1 pyramidal cells from anoxia in the rat hippocampal slice. Anesthesia & Analgesia 1998, 87: 68-71. PMID: 9661548, DOI: 10.1097/00000539-199807000-00015.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidAnesthetics, IntravenousAnimalsCell HypoxiaDose-Response Relationship, DrugElectrophysiologyFentanylMaleNeuronsPyramidal CellsRatsRats, Sprague-DawleyConceptsEffects of fentanylCA 1 pyramidal cellsMin of anoxiaAnoxic injuryControl groupHippocampal slicesPyramidal cellsRat hippocampal slice modelRat hippocampal slicesAdult Sprague-DawleyHippocampal slice modelSchaffer collateral pathwayRat hippocampal neuronsPreanoxic levelElectrophysiologic recoveryAnoxic insultCollateral pathwaysOpioid receptorsPostsynaptic populationRat hippocampusSuch injuriesSprague-DawleyHippocampal neuronsSurgical proceduresFentanyl