2017
Development, Validation, and Assessment of an Ischemic Stroke or Transient Ischemic Attack-Specific Prediction Tool for Obstructive Sleep Apnea
Sico JJ, Yaggi HK, Ofner S, Concato J, Austin C, Ferguson J, Qin L, Tobias L, Taylor S, Fragoso C, McLain V, Williams LS, Bravata DM. Development, Validation, and Assessment of an Ischemic Stroke or Transient Ischemic Attack-Specific Prediction Tool for Obstructive Sleep Apnea. Journal Of Stroke And Cerebrovascular Diseases 2017, 26: 1745-1754. PMID: 28416405, PMCID: PMC6006998, DOI: 10.1016/j.jstrokecerebrovasdis.2017.03.042.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArea Under CurveBrain IschemiaDecision Support TechniquesFemaleHumansIschemic Attack, TransientMaleMiddle AgedPolysomnographyPredictive Value of TestsPrevalencePrognosisReproducibility of ResultsRisk AssessmentRisk FactorsROC CurveSleepSleep Apnea, ObstructiveStrokeSurveys and QuestionnairesTime FactorsUnited StatesConceptsObstructive sleep apneaTransient ischemic attackHigh negative predictive valueEpworth Sleepiness ScaleNegative predictive valueIschemic strokeSleep apneaPresence of OSASleep InventoryPredictive valueSleep Apnea Clinical ScoreValidation study populationHigh blood pressureBody mass indexIschemic attackObserved apneaBerlin questionnaireStroke severityBlood pressureOvernight polysomnographyMass indexRandomized trialsClinical scoresSleep QuestionnaireMedical history
2016
Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study
Koo BB, Bravata DM, Tobias LA, Mackey JS, Miech EJ, Matthias MS, Stahl SM, Sico JJ, Fragoso C, Williams LS, Lampert R, Qin L, Yaggi HK. Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study. Cerebrovascular Diseases 2016, 41: 233-241. PMID: 26811929, DOI: 10.1159/000440736.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersBlood PressureBlood Pressure Monitoring, AmbulatoryBrain IschemiaChi-Square DistributionCholesterol, LDLConnecticutCross-Sectional StudiesFemaleHumansIndianaIschemic Attack, TransientLogistic ModelsMaleMiddle AgedOdds RatioOxygenPolysomnographyPrevalenceRandomized Controlled Trials as TopicRisk FactorsSeverity of Illness IndexSex FactorsSleepSleep Apnea, ObstructiveStrokeSympathetic Nervous SystemWakefulnessConceptsObstructive sleep apneaDiastolic blood pressureSevere obstructive sleep apneaLow-density lipoproteinBlood pressureSleep apneaSerum catecholaminesAmbulatory blood pressure monitoringBaseline diastolic blood pressureMean body mass indexB-type natriuretic peptideHigher diastolic blood pressureMore oxygen desaturationTransient ischemic attackIschemic stroke patientsAmbulatory blood pressureHistory of strokeBody mass indexC-reactive proteinBlood pressure monitoringOxygen desaturation eventsGender-stratified analysesCross-sectional analysisIschemic attackOSA frequency
2013
HIV Infection and the Risk of Acute Myocardial Infarction
Freiberg MS, Chang CC, Kuller LH, Skanderson M, Lowy E, Kraemer KL, Butt AA, Goetz M, Leaf D, Oursler KA, Rimland D, Barradas M, Brown S, Gibert C, McGinnis K, Crothers K, Sico J, Crane H, Warner A, Gottlieb S, Gottdiener J, Tracy RP, Budoff M, Watson C, Armah KA, Doebler D, Bryant K, Justice AC. HIV Infection and the Risk of Acute Myocardial Infarction. JAMA Internal Medicine 2013, 173: 614-622. PMID: 23459863, PMCID: PMC4766798, DOI: 10.1001/jamainternmed.2013.3728.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAcute myocardial infarctionRisk of AMIFramingham risk factorsUninfected veteransRisk factorsMyocardial infarctionAMI eventsHIV statusVeterans Aging Cohort Study Virtual CohortHIV-1 RNA levelsStandard Framingham risk factorsIncident acute myocardial infarctionIncidence of AMISubstance useBaseline cardiovascular diseaseCD4 cell countHepatitis C infectionBody mass indexHIV-1 RNACopies/mLHIV-positive veteransTime-updated analysisDecade of ageRace/ethnicity