2020
Sparse Data–Driven Learning for Effective and Efficient Biomedical Image Segmentation
Onofrey JA, Staib LH, Huang X, Zhang F, Papademetris X, Metaxas D, Rueckert D, Duncan JS. Sparse Data–Driven Learning for Effective and Efficient Biomedical Image Segmentation. Annual Review Of Biomedical Engineering 2020, 22: 1-27. PMID: 32169002, PMCID: PMC9351438, DOI: 10.1146/annurev-bioeng-060418-052147.Peer-Reviewed Original Research
2019
Deep learning for liver tumor diagnosis part II: convolutional neural network interpretation using radiologic imaging features
Wang CJ, Hamm CA, Savic LJ, Ferrante M, Schobert I, Schlachter T, Lin M, Weinreb JC, Duncan JS, Chapiro J, Letzen B. Deep learning for liver tumor diagnosis part II: convolutional neural network interpretation using radiologic imaging features. European Radiology 2019, 29: 3348-3357. PMID: 31093705, PMCID: PMC7243989, DOI: 10.1007/s00330-019-06214-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAlgorithmsBile Duct NeoplasmsBile Ducts, IntrahepaticCarcinoma, HepatocellularCholangiocarcinomaDeep LearningFemaleHumansImage Interpretation, Computer-AssistedLiver NeoplasmsMachine LearningMagnetic Resonance ImagingMaleMiddle AgedNeural Networks, ComputerPredictive Value of TestsProof of Concept StudyRetrospective StudiesConceptsDeep learning systemConvolutional neural networkLearning systemRelevance scoresFeature mapsPre-trained CNN modelsFeature relevance scoresMulti-phasic MRINeural network interpretationEvidence-based decision supportDeep NeuralDeep learningCNN modelLesion classifierLearning prototypeNeural networkOriginal imageSystem prototypeDecision supportLesion classificationNetwork interpretationImage voxelsIncorrect featuresLesion classesTest set
2018
Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma.
Abajian A, Murali N, Savic LJ, Laage-Gaupp FM, Nezami N, Duncan JS, Schlachter T, Lin M, Geschwind JF, Chapiro J. Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma. Journal Of Visualized Experiments 2018 PMID: 30371657, PMCID: PMC6235502, DOI: 10.3791/58382.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularHumansInjections, Intra-ArterialLiver NeoplasmsMachine LearningMaleMiddle AgedSurgery, Computer-AssistedConceptsIntra-arterial therapyN patientsHepatocellular carcinomaTrans-arterial therapiesIntra-arterial treatmentCohort of patientsStandard of careLikelihood of responseClinical research questionsSurgical resectionNew patientsTreatment responseUnivariate associationsPatientsTraining patientsInterventional radiologyTherapyCarcinomaTreatmentImage-guided therapyOutcomesFinal modelImaging dataResectionResponseLearning Generalizable Recurrent Neural Networks from Small Task-fMRI Datasets
Dvornek NC, Yang D, Ventola P, Duncan JS. Learning Generalizable Recurrent Neural Networks from Small Task-fMRI Datasets. Lecture Notes In Computer Science 2018, 11072: 329-337. PMID: 30873514, PMCID: PMC6411297, DOI: 10.1007/978-3-030-00931-1_38.Peer-Reviewed Original ResearchConceptsRecurrent neural networkNeural networkTask fMRI datasetsMedical image analysis problemsSuch deep networksImage analysis problemsTask fMRI scanTypical control subjectsDeep networkDeep learningTraining lossSmall datasetsLarge datasetsNumber of approachesAutism spectrum disorderAnalysis problemDatasetNetworkTraining runsImage analysisGeneralizable modelNon-imaging variablesSpectrum disorderFMRI analysisModel performancePredicting Treatment Response to Intra-arterial Therapies for Hepatocellular Carcinoma with the Use of Supervised Machine Learning—An Artificial Intelligence Concept
Abajian A, Murali N, Savic LJ, Laage-Gaupp FM, Nezami N, Duncan JS, Schlachter T, Lin M, Geschwind JF, Chapiro J. Predicting Treatment Response to Intra-arterial Therapies for Hepatocellular Carcinoma with the Use of Supervised Machine Learning—An Artificial Intelligence Concept. Journal Of Vascular And Interventional Radiology 2018, 29: 850-857.e1. PMID: 29548875, PMCID: PMC5970021, DOI: 10.1016/j.jvir.2018.01.769.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic AgentsCarcinoma, HepatocellularChemoembolization, TherapeuticContrast MediaDoxorubicinEthiodized OilFemaleHumansLiver NeoplasmsMachine LearningMagnetic Resonance ImagingMaleMiddle AgedNeoplasm StagingPredictive Value of TestsRetrospective StudiesSensitivity and SpecificityTreatment OutcomeConceptsTransarterial chemoembolizationHepatocellular carcinomaTreatment responseLogistic regressionClinical patient dataPatient dataIntra-arterial therapyQuantitative European AssociationMagnetic resonance imagingLiver criteriaBaseline imagingClinical variablesTumor responseTherapeutic featuresTreatment respondersBaseline MRClinical informationImaging variablesChemoembolizationTherapeutic outcomesResonance imagingResponse criteriaEuropean AssociationPatientsMR imaging
2016
Machine learning–based 3‐D geometry reconstruction and modeling of aortic valve deformation using 3‐D computed tomography images
Liang L, Kong F, Martin C, Pham T, Wang Q, Duncan J, Sun W. Machine learning–based 3‐D geometry reconstruction and modeling of aortic valve deformation using 3‐D computed tomography images. International Journal For Numerical Methods In Biomedical Engineering 2016, 33 PMID: 27557429, PMCID: PMC5325825, DOI: 10.1002/cnm.2827.Peer-Reviewed Original ResearchMeSH KeywordsAortic ValveComputer SimulationFinite Element AnalysisHumansImaging, Three-DimensionalMachine LearningTomography, X-Ray ComputedConceptsHuman expertsGeometry reconstructionHuman errorMean discrepancyPreoperative planning systemComputational modeling processReconstructed geometryFinite element model generationModel generationPatient-specific computational modelingCardiac imagesComputational modeling methodsFast feedbackComputational modeling frameworkModeling processMesh correspondencePlanning systemModeling methodMachineModeling frameworkAortic valveImagesDisease diagnosisLarge patient cohortIndividual patient needs