2022
Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic
Poghosyan H, Margaryan Y, Jeon S, Edelman EJ, Yu JB. Association between social connectedness and stress or anxiety among older cancer survivors during the 2020–2021 winter surge of the COVID-19 pandemic. Journal Of Geriatric Oncology 2022, 14: 101390. PMID: 36274031, PMCID: PMC9554341, DOI: 10.1016/j.jgo.2022.10.005.Peer-Reviewed Original Research
2021
Geographic Access to Radiation Therapy Facilities in the United States
Maroongroge S, Wallington D, Taylor P, Zhu D, Guadagnolo B, Smith B, Yu J, Ballas L. Geographic Access to Radiation Therapy Facilities in the United States. International Journal Of Radiation Oncology • Biology • Physics 2021, 112: 600-610. PMID: 34762972, DOI: 10.1016/j.ijrobp.2021.10.144.Peer-Reviewed Original ResearchConceptsRadiation therapyRT facilitiesGeographic accessOlder median ageRadiation therapy facilitiesMeasures of geographic accessU.S. populationMedian ageRT accessZIP Code Tabulation AreasState purposesLogistic regressionTherapy facilitiesHigher incomeLinear acceleratorPercentage pointsImprove accessPopulation-level measuresUnited StatesPost-operative radiation therapy for non-small cell lung cancer: A comparison of radiation therapy techniques
Jairam V, Pasha S, Soulos PR, Gross CP, Yu JB, Park HS, Decker RH. Post-operative radiation therapy for non-small cell lung cancer: A comparison of radiation therapy techniques. Lung Cancer 2021, 161: 171-179. PMID: 34607209, DOI: 10.1016/j.lungcan.2021.09.010.Peer-Reviewed Original ResearchConceptsPost-operative radiation therapyNon-small cell lung cancerCell lung cancerRadiation therapyPropensity-score matchingLA-NSCLCCardiac toxicityLung cancerAdvanced non-small cell lung cancerClinical risk factorsProportion of patientsMultivariable logistic regressionPrior treatment historyPredictors of receiptUse of IMRTConformal radiation therapyLong-term toxicityChi-squared testRadiation therapy techniquesRadiotherapy treatment techniquesUpfront surgeryElderly patientsTreatment toxicityMean ageMedicare databaseSocial Connectedness Among Medicare Beneficiaries Following the Onset of the COVID-19 Pandemic
Talcott WJ, Yu JB, Gross CP, Park HS. Social Connectedness Among Medicare Beneficiaries Following the Onset of the COVID-19 Pandemic. JAMA Internal Medicine 2021, 181: 1245-1248. PMID: 34047760, PMCID: PMC8424484, DOI: 10.1001/jamainternmed.2021.2348.Peer-Reviewed Original ResearchPrevalence of Missing Data in the National Cancer Database and Association With Overall Survival
Yang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival. JAMA Network Open 2021, 4: e211793. PMID: 33755165, PMCID: PMC7988369, DOI: 10.1001/jamanetworkopen.2021.1793.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseNon-small cell lung cancerOverall survivalCell lung cancerCancer DatabaseMedical recordsLung cancerProstate cancerBreast cancerPatient recordsComplete dataRetrospective cohort studyCohort studyCancer RegistryCommon cancerVariables of interestHigh prevalenceMAIN OUTCOMEPatientsClinical advancementReal-world data sourcesCancerPrevalenceSurvivalHeterogeneous differencesDrivers of Medicare Spending: A 15-Year Review of Radiation Oncology Charges Allowed by the Medicare Physician/Supplier Fee-for-Service Program Compared With Other Specialties
Mokhtech M, Laird JH, Maroongroge S, Zhu D, Falit B, Johnstone PAS, Mantz CA, Ennis RD, Sandler HM, Dosoretz AP, Yu JB. Drivers of Medicare Spending: A 15-Year Review of Radiation Oncology Charges Allowed by the Medicare Physician/Supplier Fee-for-Service Program Compared With Other Specialties. International Journal Of Radiation Oncology • Biology • Physics 2021, 110: 322-327. PMID: 33412264, DOI: 10.1016/j.ijrobp.2020.12.051.Peer-Reviewed Original Research
2020
Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact
Xu X, Soulos PR, Herrin J, Wang S, Pollack CE, Evans SB, Yu JB, Gross CP. Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact. Health Services Research 2020, 56: 497-506. PMID: 33070305, PMCID: PMC8143683, DOI: 10.1111/1475-6773.13572.Peer-Reviewed Original ResearchConceptsPhysician peer groupsWhole breast irradiationCF-WBIRisk-adjusted ratesBreast radiotherapyPractice patternsLow useChronic Conditions Data WarehouseDistinct practice patternsPatients' clinical characteristicsSetting of radiotherapyAdjuvant breast radiotherapyYears of ageDistinct trajectoriesImportant cost implicationsHigher useAdjuvant radiotherapyClinical characteristicsEligible womenBreast cancerCost implicationsLatent class growth analysisService beneficiariesMedicare programRadiotherapyTemporal Trends in Opioid Prescribing Patterns Among Oncologists in the Medicare Population
Jairam V, Yang DX, Pasha S, Soulos PR, Gross CP, Yu JB, Park HS. Temporal Trends in Opioid Prescribing Patterns Among Oncologists in the Medicare Population. Journal Of The National Cancer Institute 2020, 113: 274-281. PMID: 32785685, PMCID: PMC7936059, DOI: 10.1093/jnci/djaa110.Peer-Reviewed Original ResearchConceptsOpioid-prescribing ratesOpioid prescribingOpioid Prescribing PatternsOpioid-prescribing guidelinesUS opioid epidemicPalliative care providersMultivariable negative binomial regressionNoncancer populationsPrescribing patternsPrescribing ratesSymptom managementCancer survivorsOpioid epidemicDrug claimsCare providersMedicare populationMedicare beneficiariesPrescribingOncologistsNononcologistsNegative binomial regressionOpioidsBinomial regressionPatientsAnnual numberNational Patterns in Prescription Opioid Use and Misuse Among Cancer Survivors in the United States
Jairam V, Yang DX, Verma V, Yu JB, Park HS. National Patterns in Prescription Opioid Use and Misuse Among Cancer Survivors in the United States. JAMA Network Open 2020, 3: e2013605. PMID: 32804217, PMCID: PMC7431994, DOI: 10.1001/jamanetworkopen.2020.13605.Peer-Reviewed Original ResearchConceptsPrescription opioid usePrescription opioid misuseRecent cancer survivorsOpioid useCancer survivorsAdult cancer survivorsOpioid misuseUse disordersHigher prescription opioid useRecent cancer historyCancer-related painHistory of cancerPopulation-based studyNonmelanoma skin cancerDrug use disordersCross-sectional studyAlcohol use disorderLong-term misusePrescription opioidsCancer historyMAIN OUTCOMESkin cancerDrug useYounger ageCancerNationwide Patterns of Pathologic Fractures Among Patients Hospitalized With Bone Metastases
Jairam V, Lee V, Yu JB, Park HS. Nationwide Patterns of Pathologic Fractures Among Patients Hospitalized With Bone Metastases. American Journal Of Clinical Oncology 2020, 43: 720-726. PMID: 32694296, DOI: 10.1097/coc.0000000000000737.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone NeoplasmsFemaleFractures, SpontaneousHumansInpatientsMaleMiddle AgedRisk FactorsUnited StatesConceptsPathologic fractureBone metastasesMultiple myelomaUtilization Project National Inpatient SampleLonger inpatient staysMultivariable logistic regressionNational Inpatient SampleIntrahepatic bile ductsRenal pelvis cancerRenal cell carcinomaProphylactic stabilizationHospital admissionPrimary cancerBile ductInpatient stayPelvis cancerCell carcinomaInpatient SamplePrimary diagnosisRisk factorsBaseline differencesOutpatient monitoringHigh riskHealthcare costsPatientsNationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation
Lee V, Jairam V, Yu JB, Park HS. Nationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation. Scientific Reports 2020, 10: 10084. PMID: 32572113, PMCID: PMC7308286, DOI: 10.1038/s41598-020-67316-8.Peer-Reviewed Original ResearchConceptsBrain metastasesLong-term anticoagulationIntracerebral hemorrhageKidney cancerHigh riskUtilization Project Nationwide Inpatient SampleDiagnosis of ICHHospital-related characteristicsRisks of anticoagulationPrimary cancer diagnosisMultivariable logistic regressionNationwide Inpatient SampleLonger lengthDiagnosis of melanomaMann-Whitney UHemorrhagic strokeNeurologic dysfunctionConcurrent diagnosisSignificant morbiditySecondary diagnosisInpatient SampleBaseline differencesDecreased qualityAnticoagulationHealthcare costsNational trends in the management of patients with positive surgical margins at radical prostatectomy
Ghabili K, Park HS, Yu JB, Sprenkle PC, Kim SP, Nguyen KA, Ma X, Gross CP, Leapman MS. National trends in the management of patients with positive surgical margins at radical prostatectomy. World Journal Of Urology 2020, 39: 1141-1151. PMID: 32562045, DOI: 10.1007/s00345-020-03298-6.Peer-Reviewed Original ResearchConceptsAndrogen deprivation therapyPositive surgical marginsUse of ADTPost-prostatectomy radiation therapyRadiation therapySurgical marginsRadical prostatectomyInitial courseNode-negative prostate cancerPost-operative radiation therapyMultivariable logistic regression modelNational Cancer DatabaseAdverse pathologic featuresManagement of patientsPost-operative managementLogistic regression modelsDeprivation therapySurgical cancersPrimary endpointRT useSecondary endpointsPathologic characteristicsPathologic featuresUninsured statusCancer DatabaseDid quality of life for older cancer survivors improve with the turn of the century in the United States?
Mahal AR, Cramer LD, Wang EH, Wang S, Davidoff AJ, Gross CP, Yu JB. Did quality of life for older cancer survivors improve with the turn of the century in the United States? Journal Of Geriatric Oncology 2020, 12: 102-105. PMID: 32535014, DOI: 10.1016/j.jgo.2020.05.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedCancer SurvivorsHumansMaleMedicareNeoplasmsQuality of LifeSurveys and QuestionnairesSurvivorsUnited StatesConceptsPhysical component summaryMental component summary scoresComponent summary scoresHealth utilityOlder patientsComponent summaryCancer survivorsLung cancerSummary scoresEarly era patientsLung cancer survivorsHealth-related qualityOlder cancer survivorsPopulation-based registryMedicare Advantage patientsLater eraQuality of lifeERA patientsAdvantage patientsMean agePatientsLongitudinal patientSimilar outcomesPropensity scoreCancerProceedings of the ASTRO-RSNA Oligometastatic Disease Research Workshop
Yu JB, Brock KK, Campbell AM, Chen A, Diaz R, Escorcia F, Gupta G, Hrinivich WT, Joseph S, Korpics M, Onderdonk BE, Pandit-Taskar N, Wood B, Woodward WA. Proceedings of the ASTRO-RSNA Oligometastatic Disease Research Workshop. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: 539-545. PMID: 32434040, DOI: 10.1016/j.ijrobp.2020.05.018.Peer-Reviewed Original ResearchEmergency Department Visits for Firearm-Related Injuries among Youth in the United States, 2006–2015
Lee V, Camp C, Jairam V, Park HS, Yu JB. Emergency Department Visits for Firearm-Related Injuries among Youth in the United States, 2006–2015. The Journal Of Law, Medicine & Ethics 2020, 48: 67-73. PMID: 33404319, DOI: 10.1177/1073110520979403.Peer-Reviewed Original ResearchConceptsNationwide Emergency Department SampleEmergency department visitsFirearm injuriesDepartment visitsInjury dataSignificant public health problemEmergency Department SampleEmergency Department DatabasesPublic health problemFirearm-related injuriesPatient ageEmergency departmentRisk factorsDepartment databaseNumber of childrenSignificant burdenImmense burdenHealth problemsDeath dataInjuryVisitsUnited StatesBurdenDescriptive analysisSafety measures
2019
Early Impact of the Affordable Care Act and Medicaid Expansion on Racial and Socioeconomic Disparities in Cancer Care
Mahal A, Chavez J, Yang D, Kim D, Cole A, Hu J, Trinh Q, Yu J, Nguyen P, Mahal B. Early Impact of the Affordable Care Act and Medicaid Expansion on Racial and Socioeconomic Disparities in Cancer Care. American Journal Of Clinical Oncology 2019, 43: 163-167. PMID: 31904711, DOI: 10.1097/coc.0000000000000588.Peer-Reviewed Original ResearchConceptsAffordable Care ActAffordable Care Act implementationMedicaid expansionUninsured rateCare ActInsurance coverageInsurance coverage gapsMultivariate logistic regressionCoverage gapSocioeconomic disparitiesCare objectivesSociodemographic disparitiesRacial disparitiesLow-incomeNonelderly adultsLogistic regressionMedicaidBlack patientsDisparitiesEarly impactInsurancePotential benefitsPatientsCancerAffordabilityEmergency Department Visits for Opioid Overdoses Among Patients With Cancer
Jairam V, Yang DX, Yu JB, Park HS. Emergency Department Visits for Opioid Overdoses Among Patients With Cancer. Journal Of The National Cancer Institute 2019, 112: 938-943. PMID: 31845985, PMCID: PMC7492769, DOI: 10.1093/jnci/djz233.Peer-Reviewed Original ResearchConceptsOpioid-related ED visitsED visitsEmergency departmentOpioid overdoseComorbid diagnosesUtilization Project Nationwide Emergency Department SampleMultivariable logistic regression analysisNationwide Emergency Department SampleHigh opioid useOpioid-related visitsPrimary disease siteEmergency department visitsEmergency Department SampleLogistic regression analysisSubstance use disordersOpioid useDepartment visitsChronic painMultiple myelomaNeck cancerPrimary diagnosisRisk factorsPatient visitsBaseline differencesOpioid overdosesMinimum Data Elements for Radiation Oncology: An American Society for Radiation Oncology Consensus Paper
Hayman J, Dekker A, Feng M, Keole S, McNutt T, Machtay M, Martin N, Mayo C, Pawlicki T, Smith B, Kudner R, Dawes S, Yu J. Minimum Data Elements for Radiation Oncology: An American Society for Radiation Oncology Consensus Paper. Practical Radiation Oncology 2019, 9: 395-401. PMID: 31445187, DOI: 10.1016/j.prro.2019.07.017.Peer-Reviewed Original ResearchConceptsElectronic health record vendorsData elementsImprove care coordinationElectronic health recordsMinimum data elementsCare coordinationPractice staffHealth recordsRadiation oncology dataIncident learning systemAccreditation programASTRO Board of DirectorsData entryTask ForceQuality measuresAmerican Society for Radiation Oncology (ASTRODraft manuscriptRegistryDatabase architectInteroperability initiativesLegal counselLearning systemCancer treatmentHolistic approachRadiation oncologyConservative management of low‐risk prostate cancer among young versus older men in the United States: Trends and outcomes from a novel national database
Mahal A, Butler S, Franco I, Muralidhar V, Larios D, Pike L, Zhao S, Sanford N, Dess R, Feng F, D’Amico A, Spratt D, Yu J, Nguyen P, Rebbeck T, Mahal B. Conservative management of low‐risk prostate cancer among young versus older men in the United States: Trends and outcomes from a novel national database. Cancer 2019, 125: 3338-3346. PMID: 31251398, DOI: 10.1002/cncr.32332.Peer-Reviewed Original ResearchConceptsLow-risk prostate cancerPositive biopsy coresShort-term outcomesBiopsy coresProstate cancerManagement of low-risk prostate cancerOlder patientsProstate cancer-specific mortality ratesConservative managementProstate cancer-specific mortalityCancer-specific mortality ratesActive surveillance/watchful waitingRate of conservative managementOlder menCancer-specific mortalityShort-term safetyQuality-of-life implicationsDefinitive treatmentYounger patientsOverall mortalityPatientsMortality rateProstateNational databaseCancerUnderutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer
Wang C, Raldow A, Nickols N, Nguyen P, Spratt D, Dess R, Yu J, King C, Chu F, Chamie K, Litwin M, Saigal C, Reiter R, Liu S, Rettig M, Chang A, Steinberg M, Kupelian P, Kishan A. Underutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer. European Urology Oncology 2019, 4: 327-330. PMID: 31411981, DOI: 10.1016/j.euo.2019.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAgedAndrogen AntagonistsAndrogensHumansMaleMedicareProstatic NeoplasmsRetrospective StudiesUnited StatesConceptsConcomitant androgen deprivation therapyAndrogen deprivation therapyExternal beam radiotherapyDefinitive external beam radiotherapyHigh-grade prostate cancerGleason grade groupProstate cancerBeam radiotherapyDeprivation therapyGG 4NHW menDuration of androgen deprivation therapyAA menPopulation-based retrospective studyProstate cancer patientsMultiple randomized trialsNon-HispanicInverse probability treatmentSurvival benefitNon-Hispanic white menRetrospective studyRandomized trialsGrade groupRadiotherapyProbability treatment