2020
Trends in Use and Comparison of Stereotactic Body Radiation Therapy, Brachytherapy, and Dose-Escalated External Beam Radiation Therapy for the Management of Localized, Intermediate-Risk Prostate Cancer
Nguyen KA, Lee A, Patel SA, Chakravorty A, Yu JB, Kishan AU, Chang AJ. Trends in Use and Comparison of Stereotactic Body Radiation Therapy, Brachytherapy, and Dose-Escalated External Beam Radiation Therapy for the Management of Localized, Intermediate-Risk Prostate Cancer. JAMA Network Open 2020, 3: e2017144. PMID: 32970153, PMCID: PMC7516602, DOI: 10.1001/jamanetworkopen.2020.17144.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyBody radiation therapyRadiation therapyProstate cancerIntermediate-risk prostate cancerExternal beam radiation therapyManagement of LocalizedExternal beam radiotherapyUse of brachytherapyBeam radiation therapyCohort studyBeam radiotherapyTherapyDisease managementCancerBrachytherapyPatientsRadiotherapy
2019
Underutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer
Wang C, Raldow A, Nickols N, Nguyen P, Spratt D, Dess R, Yu J, King C, Chu F, Chamie K, Litwin M, Saigal C, Reiter R, Liu S, Rettig M, Chang A, Steinberg M, Kupelian P, Kishan A. Underutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer. European Urology Oncology 2019, 4: 327-330. PMID: 31411981, DOI: 10.1016/j.euo.2019.01.006.Peer-Reviewed Original ResearchConceptsConcomitant androgen deprivation therapyAndrogen deprivation therapyExternal beam radiotherapyDefinitive external beam radiotherapyHigh-grade prostate cancerGleason grade groupProstate cancerBeam radiotherapyDeprivation therapyGG 4NHW menDuration of androgen deprivation therapyAA menPopulation-based retrospective studyProstate cancer patientsMultiple randomized trialsNon-HispanicInverse probability treatmentSurvival benefitNon-Hispanic white menRetrospective studyRandomized trialsGrade groupRadiotherapyProbability treatment
2017
Travel distance and stereotactic body radiotherapy for localized prostate cancer
Mahal B, Chen Y, Sethi R, Padilla O, Yang D, Chavez J, Muralidhar V, Hu J, Feng F, Hoffman K, Martin N, Spratt D, Yu J, Orio P, Nguyen P. Travel distance and stereotactic body radiotherapy for localized prostate cancer. Cancer 2017, 124: 1141-1149. PMID: 29231964, DOI: 10.1002/cncr.31190.Peer-Reviewed Original ResearchConceptsStereotactic body radiotherapyProstate stereotactic body radiotherapyNational Cancer Data BaseLocalized prostate cancerShort-term efficacyProstate cancerTreated with definitive external beam radiotherapyDefinitive external beam radiotherapyDefinitive stereotactic body radiotherapyLong-term clinical implicationsFavorable disease characteristicsExternal beam radiotherapyAssociated with increased adjusted oddsMultivariate logistic regressionAcademic treatment centerAffluent zip codesBeam radiotherapyTreatment optionsDisease characteristicsRadiotherapyAdjusted oddsTreatment decisionsWhite raceYounger ageJoinpoint regressionTrends and clinico-sociodemographic determinants of stereotactic body radiotherapy use for localized prostate cancer: A National Cancer Database study.
Mahal B, Chen Y, Muralidhar V, Yang D, Mahal A, Yu J, Orio P, Nguyen P. Trends and clinico-sociodemographic determinants of stereotactic body radiotherapy use for localized prostate cancer: A National Cancer Database study. Journal Of Clinical Oncology 2017, 35: e545-e545. DOI: 10.1200/jco.2017.35.6_suppl.e545.Peer-Reviewed Original ResearchStereotactic body radiotherapyLocalized prostate cancerNational Cancer Data BaseGrade prostate cancerProstate cancerLow-risk disease featuresNational Cancer Database studyExternal beam radiotherapyLong-term efficacyMultivariate logistic regressionBeam radiotherapyRadiotherapy useTherapy optionsClinical factorsMultivariable adjustmentHazard ratioAcademic centersDisease characteristicsRadiotherapyDisease featuresProstateDatabase studyCancerPatientsHigher stage
2016
Changes in quality of life after radiation therapy for localized prostate cancer after dissemination of intensity modulated radiation therapy
Wang E, Wang S, Soulos P, Chen R, Kim S, Gross C, Yu J. Changes in quality of life after radiation therapy for localized prostate cancer after dissemination of intensity modulated radiation therapy. Journal Of Radiation Oncology 2016, 6: 295-300. DOI: 10.1007/s13566-016-0269-0.Peer-Reviewed Original ResearchExternal beam radiation therapyIntensity-modulated radiation therapyMental component scoreRadiation therapyProstate cancerEnd Results-Medicare Health Outcomes SurveyEra of IMRTComponent scoresImproved health-related qualityNonmetastatic prostate cancerPhysical component scoreHealth-related qualityHealth Outcomes SurveyStandard of careProstate cancer patientsExternal beam radiotherapyBeam radiation therapyQuality of lifeMethodsThe SurveillanceElderly patientsHRQOL measurementCancer patientsOutcome SurveyBeam radiotherapyLater eraNational trends and determinants of proton therapy use for prostate cancer: A National Cancer Data Base study
Mahal B, Chen Y, Efstathiou J, Muralidhar V, Hoffman K, Yu J, Feng F, Beard C, Martin N, Orio P, Nguyen P. National trends and determinants of proton therapy use for prostate cancer: A National Cancer Data Base study. Cancer 2016, 122: 1505-1512. PMID: 26970022, DOI: 10.1002/cncr.29960.Peer-Reviewed Original ResearchConceptsProton therapy useProstate cancerProton therapyTherapy useIncreasing use of proton therapyMultivariable adjustmentUse of proton therapyNational Cancer Data BaseLong-term follow-upExternal beam radiotherapyMultivariate logistic regression analysisHigh-grade diseaseNonmetastatic prostate cancerFactors associated with receiptNationwide cancer registryLogistic regression analysisBeam radiotherapyDefinitive therapyOncological therapyNonacademic centersTreated patientsClinical factorsFollow-upProstateCancer Registry
2010
Salvage external beam radiotherapy for prostate cancer after radical prostatectomy: current status and controversy.
Raldow A, Hamstra D, Kim S, Yu J. Salvage external beam radiotherapy for prostate cancer after radical prostatectomy: current status and controversy. Oncology 2010, 24: 692-700, 702. PMID: 20718248.Peer-Reviewed Original ResearchConceptsSalvage radiation therapyAdjuvant radiation therapyRadical prostatectomyProstate cancerRadiation therapyPost-operative adjuvant radiation therapyBiochemical recurrence of prostate cancerImmediate adjuvant radiation therapySalvage external beam radiotherapyEvidence of recurrent diseaseRecurrence of prostate cancerExternal beam radiotherapyCause of cancer deathRadiotherapy volumeBeam radiotherapyBiochemical recurrenceRecurrent diseaseRandomized trialsCancer deathProstatectomySide effectsProstatePatientsCancerRadiotherapy