2021
Sex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults
Chen Y, Li G, Ide J, Luo X, Li C. Sex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults. Neuroimage Reports 2021, 1: 100025. DOI: 10.1016/j.ynirp.2021.100025.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderADHD total scoreGroup 2Functional connectivityDorsal striatumGroup 3Symptom severityGroup 1Sex differencesTotal scoreFrontal gyrusRight inferior parietal gyrusRight superior frontal gyrusBasal ganglia dysfunctionCaudate functional connectivitySupplementary motor areaDorsal anterior cingulate cortexAnterior cingulate cortexSeed-based correlationSuperior frontal gyrusGreater symptom severityInferior parietal gyrusDeficit hyperactivity disorderGanglia dysfunctionInferior frontal gyrus
2018
Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers
Zhornitsky S, Ide J, Wang W, Chao H, Zhang S, Hu S, Krystal J, Li C. Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers. Brain Connectivity 2018, 8: 487-502. PMID: 30198312, PMCID: PMC6207153, DOI: 10.1089/brain.2018.0633.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestResting-state functional connectivityThalamic connectivityCaudate connectivityFrontal associationThalamic dysfunctionCaudate headProblem drinkingWhole-brain linear regressionAE scoreSubcortical structuresFunctional connectivityBilateral caudate headRight caudate headDisorders Identification TestSex differencesThalamic subdivisionsThalamic subregionsParietal associationAlcohol misuseThalamusWhite matter tractographyAUDIT scoresNondependent drinkersAlcohol expectanciesOxytocin attenuates trust as a subset of more general reinforcement learning, with altered reward circuit functional connectivity in males
Ide J, Nedic S, Wong K, Strey S, Lawson E, Dickerson B, Wald L, La Camera G, Mujica-Parodi L. Oxytocin attenuates trust as a subset of more general reinforcement learning, with altered reward circuit functional connectivity in males. NeuroImage 2018, 174: 35-43. PMID: 29486321, DOI: 10.1016/j.neuroimage.2018.02.035.Peer-Reviewed Original ResearchConceptsUltra-high field fMRIPre-existing beliefsReinforcement learningBrain encodingGeneral reinforcement learningNeuroeconomic taskIntranasal oxytocinFace of informationField fMRIFeedback learningFMRI activationExperimental paradigmNegative rewardsOrbitofrontal cortexSocial learningReward circuitBehavioral trajectoriesFunctional connectivityConnectivity analysisSocial contextSubjects' behaviorSocial relationshipsBehavioral effectsLearningBayesian expectation
2016
Abnormal reward circuitry in anorexia nervosa: A longitudinal, multimodal MRI study
Cha J, Ide J, Bowman F, Simpson H, Posner J, Steinglass J. Abnormal reward circuitry in anorexia nervosa: A longitudinal, multimodal MRI study. Human Brain Mapping 2016, 37: 3835-3846. PMID: 27273474, PMCID: PMC5448464, DOI: 10.1002/hbm.23279.Peer-Reviewed Original ResearchConceptsAnorexia nervosaWeight restorationResting-state functional MRI scansStructural connectivityInpatient weight restorationFunctional MRI scansHum Brain MappUnderweight phaseUnderweight stateWhite matter anisotropyHealthy controlsUnderweight individualsFemale inpatientsAltered connectionsMRI scansFunctional connectivityDisorder symptomsEffective connectivityIllnessReward processingEffect sizeSame timeframeInpatientsPathophysiologySymptomsClinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit
Cha J, DeDora D, Nedic S, Ide J, Greenberg T, Hajcak G, Mujica-Parodi L. Clinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit. Journal Of Neuroscience 2016, 36: 4708-4718. PMID: 27122030, PMCID: PMC6601720, DOI: 10.1523/jneurosci.1092-15.2016.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusVentromedial prefrontal cortexFrontal gyrusPrefrontal-limbic regionsAnxious individualsStimulus meaningNeurobiological responsesPrefrontal cortexFear generalization taskPrefrontal-limbic circuitsPrefrontal-limbic connectivityEmotion regulationAffective neurosciencePrefrontal-limbic systemGeneralization taskPerceptual similaritySimilarity gradientsPrefrontal regionsFMRI studyClinical anxietyAnxiety spectrumAnxiety severityVmPFCFunctional connectivityGyrus
2015
Using network dynamic fMRI for detection of epileptogenic foci
Nedic S, Stufflebeam S, Rondinoni C, Velasco T, dos Santos A, Leite J, Gargaro A, Mujica-Parodi L, Ide J. Using network dynamic fMRI for detection of epileptogenic foci. BMC Neurology 2015, 15: 262. PMID: 26689596, PMCID: PMC4687299, DOI: 10.1186/s12883-015-0514-y.Peer-Reviewed Original ResearchConceptsEpileptogenic focusHealthy controlsTemporal lobe epilepsy patientsCohort of patientsDuration of epilepsyVoxel functional connectivity analysisIntracranial EEG studiesPrevalent neurological disordersFunctional MRI methodsResting-state fMRIIpsilateral temporal poleFunctional connectivity analysisEpilepsy durationSuccessful surgeryEpileptogenic zoneFocal epilepsySeizure initiationEpilepsy patientsInterictal dischargesPatientsEpileptic regionsTemporal poleNeurological disordersFunctional connectivityImpaired memory
2011
Resting-State Functional Connectivity of the Medial Superior Frontal Cortex
Zhang S, Ide JS, Li CS. Resting-State Functional Connectivity of the Medial Superior Frontal Cortex. Cerebral Cortex 2011, 22: 99-111. PMID: 21572088, PMCID: PMC3236794, DOI: 10.1093/cercor/bhr088.Peer-Reviewed Original ResearchConceptsMedial superior frontal cortexSupplementary motor areaSuperior frontal cortexFunctional connectivityFrontal cortexMotor areaResting-state functional magnetic resonanceResting-state functional connectivityFrontal cortical functionPresupplementary motor areaFunctional magnetic resonanceSubthalamic nucleusSomatomotor areasCortical functionPreSMAAnterior partSignificant hemispheric asymmetryCaudateBehavioral tasksAnatomical boundariesCortexFuture studiesHemispheric asymmetryMagnetic resonanceSeed region