mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding
Delarue M, Brittingham G, Pfeffer S, Surovtsev I, Pinglay S, Kennedy K, Schaffer M, Gutierrez J, Sang D, Poterewicz G, Chung J, Plitzko J, Groves J, Jacobs-Wagner C, Engel B, Holt L. mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding. Cell 2018, 174: 338-349.e20. PMID: 29937223, PMCID: PMC10080728, DOI: 10.1016/j.cell.2018.05.042.Peer-Reviewed Original ResearchMeSH KeywordsCytoplasmDiffusionHEK293 CellsHumansMechanistic Target of Rapamycin Complex 1NanoparticlesParticle SizePlasmidsRheologyRibosomesRNA InterferenceRNA, Small InterferingSaccharomyces cerevisiaeTuberous Sclerosis Complex 1 Protein