2018
Subcellular Organization: A Critical Feature of Bacterial Cell Replication
Surovtsev IV, Jacobs-Wagner C. Subcellular Organization: A Critical Feature of Bacterial Cell Replication. Cell 2018, 172: 1271-1293. PMID: 29522747, PMCID: PMC5870143, DOI: 10.1016/j.cell.2018.01.014.Peer-Reviewed Original ResearchConceptsSelf-replicating entitiesCellular lifeStructured genomesDynamic spatial patternsChallenge cellsIntracellular organellesCellular replicationCytoskeletal filamentsBacterial cellsUnique biological propertiesComplex internal organizationSpatial organizationSmall formsCell replicationActive transportLiving systemsBacteriaReplicationGenomeBiological propertiesCellsSpatial patternsOrganellesPowerful meansHallmark
2015
Oufti: an integrated software package for high‐accuracy, high‐throughput quantitative microscopy analysis
Paintdakhi A, Parry B, Campos M, Irnov I, Elf J, Surovtsev I, Jacobs-Wagner C. Oufti: an integrated software package for high‐accuracy, high‐throughput quantitative microscopy analysis. Molecular Microbiology 2015, 99: 767-777. PMID: 26538279, PMCID: PMC4752901, DOI: 10.1111/mmi.13264.Peer-Reviewed Original ResearchConceptsSingle-cell studiesOpen-source software packageGraphical user interfaceComplex subcellular organizationSoftware packageImage analysisUser interfaceMassive datasetsCellular functionsSubcellular organizationBacterial researchHigh-throughput analysisTouching cellsMicrobial cellsSubpixel precisionInteractive modulesComputational skillsComputational solutionPost-processing analysisPhenotypic variabilityFluorescence signalQuantitative microscopy analysisCell morphologyAutomated MeasurementConfluent samples