Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis
Surovtsev I, Morgan J, Lindahl P. Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis. PLOS Computational Biology 2008, 4: e1000102. PMID: 18604268, PMCID: PMC2432035, DOI: 10.1371/journal.pcbi.1000102.Peer-Reviewed Original ResearchConceptsSame chemical modelMonomeric unitsPolymeric ringsRapid assemblyChemical modelProkaryotic cytokinesisMembrane surfaceFree energyUnfavorable processMonomeric FtsZKinetic modelingMechanistic complexityInterfacial reactionRingVivo behaviorDynamic steady stateMonomeric subunitsFtsZ polymerizationHydrolysisReactionRing formsAssembly