Israel Franco, MD, FAAP, FACS
Professor Adjunct of Clinical UrologyCards
About
Research
Publications
2024
Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine
Shain S, Gitlin J, Pantazis A, Fine R, Horowitz M, Friedman S, Zelkovic P, Dyer L, Schlussel R, Freyle J, Fang A, Sommer J, Franco I. Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine. Journal Of Pediatric Urology 2024, 20: 603.e1-603.e8. PMID: 38871547, DOI: 10.1016/j.jpurol.2024.05.024.Peer-Reviewed Original ResearchVancouver Symptom ScoreInternational Children's Continence SocietyWet nightsDesmopressin treatmentCombination therapyResponse rateIntent-to-treat response rateCombination therapy of desmopressinFirst-line medical therapyEfficacy of adjunctive therapyGroup IMPComplete response rateTreated with desmopressinCohort of patientsContinence successPrescribed desmopressinEnuresis patientsMedical therapyNighttime drynessChart reviewAdjunctive therapyConclusion A combinationDesmopressinOxybutyninPediatric populationSize Matters: Total Testicular Volume Predicts Sperm Count in Tanner V Varicocele Patients
Fang A, Franco I, Pizzuti J, Boroda J, Friedman S, Fine R, Horowitz M, Schlussel R, Landau-Dyer L, Zelkovic P, Freyle J, Sommer J, Gitlin J. Size Matters: Total Testicular Volume Predicts Sperm Count in Tanner V Varicocele Patients. Journal Of Pediatric Urology 2024 PMID: 38876892, DOI: 10.1016/j.jpurol.2024.05.012.Peer-Reviewed Original ResearchNegative predictive valueSemen analysisAbnormal SAPredictive valueSperm countSurgical interventionTesticular volumeRetrospective single-center chart reviewSingle-center chart reviewOdds ratioAppropriateness of surgical interventionLeft-sided varicoceleMotile sperm countAbnormal semen analysisReceiver operating characteristic analysisPrevalence of varicoceleMultivariate logistic regressionTotal testicular volumeYouden's J statisticVaricocele gradeMedian ageChart reviewUltrasound resultsYounger patientsRisk stratificationA comparison of 467 uroflowmetry results in repaired hypospadias vs. normal male flows
Boroda J, Gitlin J, Fang A, Zelkovic P, Reda E, Friedman S, Fine R, Horowitz M, Schlussel R, Landau-Dyer L, Freyle J, Franco I. A comparison of 467 uroflowmetry results in repaired hypospadias vs. normal male flows. Journal Of Pediatric Urology 2024, 20: 690.e1-690.e7. PMID: 38772843, DOI: 10.1016/j.jpurol.2024.04.017.Peer-Reviewed Original ResearchHypospadias repair surgeryRepair patientsUroflowmetry parametersRepair surgeryUroflowmetry studiesUroflowmetry resultsBinary logistic regressionMeatal stenosisUrethral strictureRepair groupStudy design Retrospective chart reviewLogistic regressionDesign Retrospective chart reviewDistal hypospadias casesObstructed urinary flowRetrospective chart reviewPresence of complicationsIdentification of complicationsObstructed urine flowPediatric nomogramsHypospadias patientsObstructive complicationsRepairing hypospadiasUrethral meatusHypospadias casesImmune checkpoint inhibitors in high‐grade upper tract urothelial carcinoma: Paradigm shift emphasizing organ preservation
Khalil M, Fishman A, Komorowski A, Franco I, Grasso M. Immune checkpoint inhibitors in high‐grade upper tract urothelial carcinoma: Paradigm shift emphasizing organ preservation. BJUI Compass 2024, 5: 490-496. PMID: 38751949, PMCID: PMC11090768, DOI: 10.1002/bco2.335.Peer-Reviewed Original ResearchImmune check point inhibitorsHigh-grade upper tract urothelial carcinomaUpper tract urothelial carcinomaMetastasis-free survival ratesGroup 2Group 1Survival rateUrothelial carcinomaSurvival outcomesMedian follow-up periodImpact of clinical characteristicsCheck-point inhibitorsImmune checkpoint inhibitorsEndoscopically treated patientsInitial tumor sizeImprove survival outcomesOverall survival rateKaplan-Meier analysisFollow-up periodImproved survival ratesCheckpoint inhibitorsPoint inhibitorsExtirpative surgeryTumor sizeClinical characteristics
2023
Changes in Autonomic Nervous System Activity in Children With Spina Bifida: A Case-Control Study
Kim B, Franco I, Lee Y, Han S, Kim S. Changes in Autonomic Nervous System Activity in Children With Spina Bifida: A Case-Control Study. International Neurourology Journal 2023, 27: 192-199. PMID: 37798886, PMCID: PMC10556434, DOI: 10.5213/inj.2346080.040.Peer-Reviewed Original ResearchHeart rate variability parametersControl groupSpina bifidaNN intervalsAutonomic nervous system dysfunctionAutonomic nervous system activityBladder filling phaseVideo-urodynamic studyNervous system dysfunctionCase-control studyNervous system activityR interval differencesLF/HF valuesVariability parametersSympathetic preponderanceNeurogenic bladderUrodynamic studiesSympathetic activityVesicoureteral refluxSystem dysfunctionParasympathetic activityPatientsSpina bifida groupBladderBifidaIs it time to reconsider how we document pediatric uroflow studies?: A study from the SPU Voiding Dysfunction task force
Van Batavia J, Pohl H, Farhat W, Chiang G, BaniHani A, Collett-Gardere T, Franco I. Is it time to reconsider how we document pediatric uroflow studies?: A study from the SPU Voiding Dysfunction task force. Journal Of Pediatric Urology 2023, 19: 546-554. PMID: 37302925, DOI: 10.1016/j.jpurol.2023.04.018.Peer-Reviewed Original ResearchInitial outcomes using a novel bedwetting alarm (Gogoband®) that utilizes real time artificial intelligence to wake users prior to wetting
Franco I, Coble J. Initial outcomes using a novel bedwetting alarm (Gogoband®) that utilizes real time artificial intelligence to wake users prior to wetting. Journal Of Pediatric Urology 2023, 19: 557.e1-557.e8. PMID: 37217414, DOI: 10.1016/j.jpurol.2023.04.024.Peer-Reviewed Original ResearchReply by Authors
Franco I, Hoebeke P, Dobremez E, Titanji W, Geib T, Jenkins B, Yushmanova I, Austin P. Reply by Authors. Journal Of Urology 2023, 209: 783-784. PMID: 36891836, DOI: 10.1097/ju.0000000000003157.03.Peer-Reviewed Original ResearchMP43-18 ADOLESCENT VARICOCELE: EFFECTS OF VEIN SIZE AND ARTERIAL FLOW RATE ON SEMINAL PARAMETERS
Ocal S, Sheikh A, Pizzuti J, Fang A, Boroda J, Friedman S, Fine R, Horowitz M, Fine R, Sclussel R, Dyer L, Zelkovic P, Freyle J, Franco I, Gitlin J. MP43-18 ADOLESCENT VARICOCELE: EFFECTS OF VEIN SIZE AND ARTERIAL FLOW RATE ON SEMINAL PARAMETERS. Journal Of Urology 2023, 209: e608. DOI: 10.1097/ju.0000000000003289.18.Peer-Reviewed Original ResearchMP70-01 MANAGEMENT OF THE REFRACTORY NOCTURNAL ENURESIS PATIENT TO DESMOPRESSIN IN A PEDIATRIC POPULATION: DESMOPRESSIN + OXYBUTYNIN VS. DESMOPRESSIN + IMIPRAMINE
Shain S, Gitlin J, Pantazis A, Fine R, Horowitz M, Friedman S, Zelkovic P, Dyer L, Schlussel R, Freyle J, Fang A, Sommer J, Franco I. MP70-01 MANAGEMENT OF THE REFRACTORY NOCTURNAL ENURESIS PATIENT TO DESMOPRESSIN IN A PEDIATRIC POPULATION: DESMOPRESSIN + OXYBUTYNIN VS. DESMOPRESSIN + IMIPRAMINE. Journal Of Urology 2023, 209: e1003. DOI: 10.1097/ju.0000000000003338.01.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
Links & Media
News
- July 28, 2023
Yale Urology Research [Q2: April-June 2023]
- June 12, 2023Source: Physician's Weekly / Journal of Pediatric Urology
Is It Time To Reconsider How We Document Pediatric Uroflow Studies?
- May 03, 2023
17 Yale Urology Affiliated Physicians Named “Top Doctors” for 2023
- April 20, 2023
Yale Urology Research [Q1: January-March 2023]