2021
Age-based outcomes of autogenous fistulas for hemodialysis access
Arhuidese I, King R, Elemuo C, Agbonkhese G, Calero A, Malas M. Age-based outcomes of autogenous fistulas for hemodialysis access. Journal Of Vascular Surgery 2021, 74: 1636-1642. PMID: 34298119, DOI: 10.1016/j.jvs.2021.06.477.Peer-Reviewed Original ResearchConceptsPrimary assisted patencySecondary patencyPopulation-based cohortAssisted patencyFistula maturationPrimary patencyAutogenous fistulasPatient survivalIncreasing agePopulation-based cohort of patientsUnited States Renal Database SystemArteriovenous access creationLog-rank testCohort of patientsCohort of HD patientsCox regression analysisRetrospective cohort studyRisk-adjusted analysisAccess maturationAccess creationPrimary assistedKaplan-MeierFistula useClinical statusHD access
2020
Outcomes of autogenous fistulas and prosthetic grafts for hemodialysis access in diabetic and nondiabetic patients
Arhuidese I, Purohit A, Elemuo C, Parkerson G, Shames M, Malas M. Outcomes of autogenous fistulas and prosthetic grafts for hemodialysis access in diabetic and nondiabetic patients. Journal Of Vascular Surgery 2020, 72: 2088-2096. PMID: 32276026, DOI: 10.1016/j.jvs.2020.02.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel Prosthesis ImplantationDatabases, FactualDiabetic NephropathiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedPostoperative ComplicationsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsProsthetic graft infectionAutogenous fistulasSecondary patencyProsthetic graftsNondiabetic patientsPopulation-based cohortGraft infectionPrimary patencyPrimary assistedHemodialysis accessPopulation-based cohort of patientsUnited States Renal Database SystemCohort of hemodialysis patientsPrimary fistula patencyPrimary assisted patencyLog-rank testKaplan-Meier analysisCohort of patientsCox regression analysisRetrospective cohort studyStudent's t-testEffects of diabetesProsthetic graft patencyAssisted patencyGraft recipientsAge-related outcomes of arteriovenous grafts for hemodialysis access
Arhuidese I, Beaulieu R, Aridi H, Locham S, Baldwin E, Malas M. Age-related outcomes of arteriovenous grafts for hemodialysis access. Journal Of Vascular Surgery 2020, 72: 643-650. PMID: 32067881, DOI: 10.1016/j.jvs.2019.10.096.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualDevice RemovalFemaleGraft Occlusion, VascularHumansKidney Failure, ChronicMaleMiddle AgedProsthesis-Related InfectionsRenal DialysisReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPrimary assisted patencyPopulation-based cohortGraft infectionAssisted patencySecondary patencyPrimary patencyNo significant differenceArteriovenous graftsHemodialysis accessOutcomes of arteriovenous graftsAge-related outcomesOlder age categoriesCohort of hemodialysis patientsProsthetic graft infectionArteriovenous graft placementEnd-stage renal diseaseLog-rank testPrevalence of end-stage renal diseaseKaplan-Meier analysisSignificant differenceCox regression analysisRetrospective cohort studyOlder ageGraft excisionU.S. Renal Data System
2019
Gender-Based Utilization and Outcomes of Autogenous Fistulas and Prosthetic Grafts for Hemodialysis Access
Arhuidese I, Faateh M, Meshkin R, Calero A, Shames M, Malas M. Gender-Based Utilization and Outcomes of Autogenous Fistulas and Prosthetic Grafts for Hemodialysis Access. Annals Of Vascular Surgery 2019, 65: 196-205. PMID: 31626935, DOI: 10.1016/j.avsg.2019.08.083.Peer-Reviewed Original ResearchMeSH KeywordsAgedArteriovenous Shunt, SurgicalBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleGraft Occlusion, VascularHealthcare DisparitiesHumansKidney Failure, ChronicMaleMiddle AgedPractice Patterns, Physicians'Prosthesis-Related InfectionsRenal DialysisRetrospective StudiesRisk FactorsSex FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsArteriovenous fistulaHD cathetersPatient survivalAssociated with lower patencyOutcomes of arteriovenous fistulaMultivariate Cox regression analysisCohort of hemodialysisArteriovenous fistula maturationCox regression analysisLow patencyInitiation of HDRisk-adjusted analysisUnited States Renal Data SystemPopulation-based cohortPrimary-assistedAccess maturationAutogenous fistulasAVF maturationNo significant differenceConduit patencyKaplan-MeierHD accessRetrospective analysisProsthetic graftsCatheterSurvival after major lower extremity amputation in patients with end-stage renal disease
Arhuidese I, Nejim B, Aji E, Canner J, Malas M. Survival after major lower extremity amputation in patients with end-stage renal disease. Journal Of Vascular Surgery 2019, 70: 1291-1298. PMID: 31543169, DOI: 10.1016/j.jvs.2018.12.055.Peer-Reviewed Original ResearchConceptsKnee amputeesKnee amputationBurden of peripheral artery diseaseLower extremity amputationEstimates of life expectancyEnd-stage renal diseaseRisk-adjusted mortalityAmputation levelExtremity amputationRace-specific differencesRT recipientsHealthcare providersPeripheral arterial diseaseHD patientsLong-term mortalityUnited States Renal Data SystemMedian survivalBKAKneeHispanicsLife expectancyRenal transplantationMLEAAmputationCardiovascular diseaseOutcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis
Nejim B, Hicks C, Arhuidese I, Locham S, Dakour-Aridi H, Malas M. Outcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis. Annals Of Vascular Surgery 2019, 63: 209-217. PMID: 31349053, DOI: 10.1016/j.avsg.2019.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseProgression-Free SurvivalRenal DialysisRetrospective StudiesRisk FactorsSaphenous VeinTime FactorsVascular PatencyConceptsLower extremity bypassEnd-stage renal diseaseKT recipientsPrimary patencyDialysis therapyAmputation-free survivalKidney transplantationVascular Quality Initiative databaseRisk-adjusted hazardsKidney transplant recipientsPositive effects of KTRisk of mortalityEffects of KTRisk of amputationLower-extremity bypassSurgical outcomesTransplant recipientsBaseline characteristicsBypass proceduresDialysis patientsRenal diseaseComparative efficacyKT groupDT groupPatientsVascular access for hemodialysis in the elderly
Arhuidese I, Cooper M, Rizwan M, Nejim B, Malas M. Vascular access for hemodialysis in the elderly. Journal Of Vascular Surgery 2019, 69: 517-525.e1. PMID: 30683199, DOI: 10.1016/j.jvs.2018.05.219.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel Prosthesis ImplantationCatheterization, Central VenousClinical Decision-MakingDatabases, FactualFemaleGraft Occlusion, VascularHumansKidney Failure, ChronicLife ExpectancyMalePatient SelectionQuality of LifeRenal DialysisRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsArteriovenous fistulaArteriovenous graftsElderly patientsPopulation-based cohort of elderly patientsHD cathetersMedian time to maturationOutcomes of arteriovenous fistulaUnited States Renal Database SystemCohort of elderly patientsMultivariate Cox regression analysisCatheter-free dialysisPre-emptive surgeryPrimary assisted patencyKaplan-Meier analysisCox regression analysisStudent's t-testPopulation-based cohortAssisted patencyTolerate surgerySecondary patencyPrimary patencySurgical riskModes of HDConduit patencyRetrospective analysis
2018
Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants
Arhuidese I, Nejim B, Locham S, Malas M. Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants. Journal Of Vascular Surgery 2018, 69: 850-856. PMID: 30583904, DOI: 10.1016/j.jvs.2018.05.252.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsInfrainguinal bypass surgeryRenal transplantationRT patientsPatient survivalOutcome of infrainguinal bypass surgeryHD patientsBenefits of renal transplantationLimb salvageEnd-stage renal diseaseCox regression analysisLong-term outcomesEvaluate 30-dayRisk-adjusted analysisPopulation-based cohortCritical limb ischemiaU.S. Renal Data SystemRetrospective reviewBypass surgeryKaplan-MeierSurgery outcomesPatient-level riskRenal diseaseHemodialysis patientsLimb ischemiaPatientsAggressive infrainguinal revascularization in renal transplant patients is justifiable
Craig-Schapiro R, Nejim B, Arhuidese I, Malas M. Aggressive infrainguinal revascularization in renal transplant patients is justifiable. American Journal Of Transplantation 2018, 18: 1718-1725. PMID: 29288558, DOI: 10.1111/ajt.14636.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPatient SelectionPostoperative ComplicationsPrognosisReoperationRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsVascular GraftingVascular PatencyConceptsCritical limb ischemiaRenal transplant patientsTransplant patientsNontransplant patientsLimb ischemiaPrimary patencyInfrainguinal revascularizationRisk factorsMultivariate Cox regression analysisVascular Quality Initiative databaseEnd-stage renal diseaseDistal bypassCox regression analysisOutcomes of lower extremity revascularizationPrimary patency lossLower extremity revascularizationAmputation-free survivalLimb salvage outcomesAssociated with limb lossOverall survivalProsthetic conduitVein conduitPatency lossRenal diseaseInfrainguinal bypass
2017
Long-term outcomes after autogenous versus synthetic lower extremity bypass in patients on hemodialysis
Arhuidese I, Hicks C, Locham S, Obeid T, Nejim B, Malas M. Long-term outcomes after autogenous versus synthetic lower extremity bypass in patients on hemodialysis. Surgery 2017, 162: 1071-1079. PMID: 28712733, DOI: 10.1016/j.surg.2017.04.026.Peer-Reviewed Original ResearchConceptsLong-term outcomesBypass operationProsthetic conduitHemodialysis patientsAutogenous conduitLimb salvageHigh-risk population of patientsEvaluate long-term outcomesCohort of hemodialysis patientsPrimary-assisted patencyFemoral-tibialType of bypassCox regression analysisLower extremity bypassPopulation of patientsUnited States Renal Data SystemHigh-risk populationPatient's life expectancyPopulation-based cohortCritical limb ischemiaPopliteal-tibial bypassSecondary patencyPrimary patencyConduit optionsPostoperative outcomes
2016
Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients
Cooper M, Arhuidese I, Obeid T, Hicks C, Canner J, Malas M. Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients. JAMA Surgery 2016, 151: 947-952. PMID: 27366897, DOI: 10.1001/jamasurg.2016.1504.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAsymptomatic DiseasesDatabases, FactualEndarterectomy, CarotidFemaleHeart FailureHispanic or LatinoHumansKidney Failure, ChronicMaleMiddle AgedMobility LimitationMyocardial InfarctionPostoperative PeriodPulmonary Disease, Chronic ObstructiveRenal DialysisRetrospective StudiesRisk FactorsSex FactorsSmokingStrokeSurvival RateTime FactorsUnited StatesConceptsLong-term outcomesRisk of carotid endarterectomyAsymptomatic patientsLong-term strokeSymptomatic patientsCarotid endarterectomyDialysis patientsPerioperative strokeCohort of symptomatic patientsHistory of congestive heart failureMedian follow-up timePredictor of long-term mortalityMyocardial infarctionAssociated with poor outcomesDialysis-dependent patientsFollow-up timeOutcomes of carotid endarterectomyCox regression analysisCongestive heart failurePredictors of perioperative strokeLong-term mortalityChronic obstructive pulmonary diseaseDecrease stroke riskObstructive pulmonary diseasePatient-important
2015
Quality Improvement Targets for Regional Variation in Surgical End-Stage Renal Disease Care
Zarkowsky DS, Hicks CW, Arhuidese I, Canner JK, Obeid T, Qazi U, Schneider E, Abularrage CJ, Black JH, Freischlag JA, Malas MB. Quality Improvement Targets for Regional Variation in Surgical End-Stage Renal Disease Care. JAMA Surgery 2015, 150: 764-770. PMID: 26107005, DOI: 10.1001/jamasurg.2015.1126.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseUS Renal Data SystemFirst hemodialysisNephrology careAVF accessMortality hazardEnd-stage renal disease careLogistic regressionCongestive heart failureRenal replacement therapyMultivariable logistic regressionArteriovenous fistula accessQuality improvement targetsPatient comorbiditiesHeart failurePatient characteristicsRenal diseaseDisease careESRD mortalityReplacement therapyFistula accessUnivariate analysisRetrospective analysisBest practice guidelinesMAIN OUTCOMEVascular access modifies the protective effect of obesity on survival in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Qazi U, Botchey I, Zarkowsky D, Reifsnyder T, Malas M. Vascular access modifies the protective effect of obesity on survival in hemodialysis patients. Surgery 2015, 158: 1628-1634. PMID: 26126794, DOI: 10.1016/j.surg.2015.04.036.Peer-Reviewed Original ResearchConceptsBody mass indexEnd-stage renal diseaseNormal body mass indexProtective effect of obesityHigher body mass indexEffect of obesityObesity paradoxProtective effect of increasing BMIEffect of increased BMIBody mass index statusMass indexHD accessProtective effectAssociated with lower mortalityPropensity score matching analysisSurvival of patientsScore matching analysisSurvival benefitImproved survivalRetrospective studyHemodialysis accessInitiate hemodialysisPatient backgroundRenal diseaseCox regressionTrends in Incident Hemodialysis Access and Mortality
Malas MB, Canner JK, Hicks CW, Arhuidese IJ, Zarkowsky DS, Qazi U, Schneider EB, Black JH, Segev DL, Freischlag JA. Trends in Incident Hemodialysis Access and Mortality. JAMA Surgery 2015, 150: 441-448. PMID: 25738981, DOI: 10.1001/jamasurg.2014.3484.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseHemodialysis cathetersArteriovenous fistulaArteriovenous graftsLower mortalityRenal diseaseVascular accessHD outcomesNational Kidney Foundation Kidney Disease Outcomes Quality InitiativeKidney Foundation Kidney Disease Outcomes Quality InitiativeMultivariable Cox proportional hazards modelsPrior renal replacement therapyUS Renal Data SystemCox proportional hazards modelArteriovenous fistula useIncident HD patientsInitiation of hemodialysisRetrospective cohort studyRenal replacement therapyProportional hazards modelFistula useCohort studySurvival benefitHD patientsPropensity score-matching technique