2018
Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era
Arhuidese I, Faateh M, Nejim B, Locham S, Abularrage C, Malas M. Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era. JAMA Surgery 2018, 153: 252-259. PMID: 29117272, PMCID: PMC5885921, DOI: 10.1001/jamasurg.2017.4477.Peer-Reviewed Original ResearchConceptsPrimary carotid endarterectomyRedo carotid endarterectomyAsymptomatic patientsSymptomatic patientsCarotid endarterectomyMyocardial infarctionProspective cohort of patientsPoint of careCohort of patientsPerioperative myocardial infarctionRisk of deathAsymptomatic carotid stenosisVascular Quality InitiativeRisk of strokeExcess riskMain OutcomesSociety for Vascular SurgeryClinicians' expectationsCommunity hospitalProfessional guidelinesConsecutive patientsProspective cohortNo significant differenceEndovascular therapyQuality Initiative
2017
Fixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study
Obeid T, Alshaikh H, Nejim B, Arhuidese I, Locham S, Malas M. Fixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study. Journal Of Vascular Surgery 2017, 65: 1398-1406.e1. PMID: 28216356, DOI: 10.1016/j.jvs.2016.11.062.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplastyAsymptomatic DiseasesCarotid StenosisChi-Square DistributionDatabases, FactualDecision Support TechniquesEndarterectomy, CarotidFemaleHospital CostsHumansMaleMiddle AgedModels, EconomicPatient SelectionProcess Assessment, Health CarePropensity ScoreRetrospective StudiesStentsTime FactorsTreatment OutcomeUnited StatesConceptsCost of carotid artery stentingSymptomatic patientsHospital costsPropensity score matchingSymptomatic statusScore matchingPremier Perspective databaseCarotid artery stentingComorbidities of patientsStudent's t-testIn-hospital costsActual hospital costsAsymptomatic patientsSurgeon specialtyHospital characteristicsMale patientsCosts of carotid endarterectomyAsymptomatic cohortPerspective databaseArtery stentingPrimary outcomeCarotid endarterectomyPatientsClinical comorbiditiesHospital discharge
2016
Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients
Cooper M, Arhuidese I, Obeid T, Hicks C, Canner J, Malas M. Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients. JAMA Surgery 2016, 151: 947-952. PMID: 27366897, DOI: 10.1001/jamasurg.2016.1504.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAsymptomatic DiseasesDatabases, FactualEndarterectomy, CarotidFemaleHeart FailureHispanic or LatinoHumansKidney Failure, ChronicMaleMiddle AgedMobility LimitationMyocardial InfarctionPostoperative PeriodPulmonary Disease, Chronic ObstructiveRenal DialysisRetrospective StudiesRisk FactorsSex FactorsSmokingStrokeSurvival RateTime FactorsUnited StatesConceptsLong-term outcomesRisk of carotid endarterectomyAsymptomatic patientsLong-term strokeSymptomatic patientsCarotid endarterectomyDialysis patientsPerioperative strokeCohort of symptomatic patientsHistory of congestive heart failureMedian follow-up timePredictor of long-term mortalityMyocardial infarctionAssociated with poor outcomesDialysis-dependent patientsFollow-up timeOutcomes of carotid endarterectomyCox regression analysisCongestive heart failurePredictors of perioperative strokeLong-term mortalityChronic obstructive pulmonary diseaseDecrease stroke riskObstructive pulmonary diseasePatient-important
2014
Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis
Hicks CW, Canner JK, Arhuidese I, Glebova NO, Schneider E, Qazi U, Perler B, Malas MB. Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis. Journal Of Vascular Surgery 2014, 60: 1585-1592. PMID: 25238724, DOI: 10.1016/j.jvs.2014.08.056.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArea Under CurveAsymptomatic DiseasesBlood Flow VelocityCarotid Artery, CommonCarotid Artery, InternalCarotid StenosisChi-Square DistributionDecision Support TechniquesDisease ProgressionFemaleHumansMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProportional Hazards ModelsRegional Blood FlowRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsUltrasonography, Doppler, DuplexConceptsAsymptomatic carotid artery stenosisICA/CCA ratioCarotid artery stenosisInternal carotid arteryDisease progressionEnd-diastolic velocityPeak systolic velocityRisk prediction modelCCA ratioArtery stenosisSystolic velocityRisk factorsInitial peak systolic velocityProportional hazards regression modelsHigh-risk patientsRisk of progressionRisk-stratify patientsHazards regression modelsSignificant independent predictorsICA/CCACharacteristic curve analysisClinical prediction modelCarotid artery ratioIndependent predictorsDuplex imagingRisk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy
Hicks C, Talbott K, Canner J, Qazi U, Arhuidese I, Glebova N, Freischlag J, Perler B, Malas M. Risk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy. Annals Of Vascular Surgery 2014, 29: 1-8. PMID: 24530720, DOI: 10.1016/j.avsg.2014.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyAsymptomatic DiseasesBaltimoreCarotid StenosisChi-Square DistributionDisease ProgressionDrug Therapy, CombinationEndarterectomy, CarotidFemaleHumansIncidenceIschemic Attack, TransientLinear ModelsMaleMultivariate AnalysisPlatelet Aggregation InhibitorsPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexSmokingStentsStrokeTertiary Care CentersTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexConceptsProgression to severe stenosisAsymptomatic carotid artery stenosisDual antiplatelet therapyCarotid artery stenosisDisease progressionRisk factorsSevere stenosisIncidence of symptomsAntiplatelet therapyArtery stenosisPatient populationMean follow-up timeRisk of disease progressionSevere diseaseCox proportional hazards regression modelsRisk of progressionProportional hazards regression modelsFollow-up timeCarotid artery duplexAll-cause mortalityHazards regression modelsImproved medical therapyTransient ischemic attackTobacco useAsymptomatic carotid disease