2020
Safety of carotid artery revascularization procedures in patients with atrial fibrillation
Nejim B, Mathlouthi A, Weaver L, Faateh M, Arhuidese I, Malas M. Safety of carotid artery revascularization procedures in patients with atrial fibrillation. Journal Of Vascular Surgery 2020, 72: 2069-2078.e4. PMID: 32471737, DOI: 10.1016/j.jvs.2020.01.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCarotid Artery DiseasesCerebral HemorrhageCross-Sectional StudiesDatabases, FactualEndarterectomy, CarotidEndovascular ProceduresFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsCarotid artery stentingInternational Classification of DiseasesClinical Modification codesClassification of DiseasesOdds of intracerebral hemorrhagePredictors of ischemic strokeIntracerebral hemorrhageMultivariate logistic modelIn-hospital strokeCarotid artery diseaseCarotid endarterectomyHospital sizeAFib patientsInternational ClassificationModification codesHealthcare databasesMedication useStatistically significant predictorsAdjusted analysesAtrial fibrillationRandomized clinical trialsArtery diseasePremier Healthcare DatabaseAssociated with worse postoperative outcomesCarotid artery revascularization procedures
2019
Reply
Wiske C, Arhuidese I, Malas M, Patterson R. Reply. Journal Of Vascular Surgery 2019, 69: 626-627. PMID: 30683207, DOI: 10.1016/j.jvs.2018.10.057.Peer-Reviewed Original ResearchEndarterectomy, Carotid
2018
Comparing the efficacy of shunting approaches and cerebral monitoring during carotid endarterectomy using a national database
Wiske C, Arhuidese I, Malas M, Patterson R. Comparing the efficacy of shunting approaches and cerebral monitoring during carotid endarterectomy using a national database. Journal Of Vascular Surgery 2018, 68: 416-425. PMID: 29571621, DOI: 10.1016/j.jvs.2017.11.077.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBlood Pressure DeterminationCarotid Artery DiseasesCerebrovascular CirculationChi-Square DistributionDatabases, FactualElectroencephalographyEndarterectomy, CarotidFemaleHospital MortalityHumansIntraoperative Neurophysiological MonitoringLength of StayLogistic ModelsMaleMonitoring, IntraoperativeMultivariate AnalysisOdds RatioPractice Patterns, Physicians'Retrospective StudiesRisk FactorsStrokeSurgeonsTime FactorsTreatment OutcomeUnited StatesConceptsRate of in-hospital deathIn-hospital deathShunt groupPractice patternsRoutine shuntingCerebral monitoringReturn to the operating roomRisk factorsPostoperative length of stayVascular Quality Initiative databaseShorter postoperative length of stayPressure monitoringVascular Quality Initiative registryMultivariate logistic regression modelCerebral monitoring techniquesRisk-adjusted analysisPatient risk factorsMonitoring groupLow-frequency outcomesRate of strokeNational databaseLength of stayConcomitant proceduresSurgical approachRe-explorationRisks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era
Arhuidese I, Faateh M, Nejim B, Locham S, Abularrage C, Malas M. Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era. JAMA Surgery 2018, 153: 252-259. PMID: 29117272, PMCID: PMC5885921, DOI: 10.1001/jamasurg.2017.4477.Peer-Reviewed Original ResearchConceptsPrimary carotid endarterectomyRedo carotid endarterectomyAsymptomatic patientsSymptomatic patientsCarotid endarterectomyMyocardial infarctionProspective cohort of patientsPoint of careCohort of patientsPerioperative myocardial infarctionRisk of deathAsymptomatic carotid stenosisVascular Quality InitiativeRisk of strokeExcess riskMain OutcomesSociety for Vascular SurgeryClinicians' expectationsCommunity hospitalProfessional guidelinesConsecutive patientsProspective cohortNo significant differenceEndovascular therapyQuality Initiative
2017
Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy?
Nejim B, Aridi H, Locham S, Arhuidese I, Hicks C, Malas M. Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy? Journal Of Vascular Surgery 2017, 66: 1735-1748.e1. PMID: 28666824, DOI: 10.1016/j.jvs.2017.04.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarotid StenosisChi-Square DistributionEndarterectomy, CarotidEndovascular ProceduresFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProportional Hazards ModelsRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsTime FactorsTreatment OutcomeUnited StatesConceptsContralateral carotid artery occlusionCarotid artery occlusionCarotid artery stenting patientsCarotid artery stentingArtery occlusionCarotid endarterectomyRisk of strokeAsymptomatic patientsSymptomatic patientsHazard ratioOdds ratioHigh riskMultivariate logistic regression analysisContralateral carotid occlusionLog-rank testVascular Quality Initiative (VQI) registryCohort of patientsRisk of ipsilateral strokeCenters for MedicareShort-term outcomesCarotid artery revascularizationCarotid endarterectomy patientsHistory of strokeLogistic regression analysisCox proportional hazardsFixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study
Obeid T, Alshaikh H, Nejim B, Arhuidese I, Locham S, Malas M. Fixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study. Journal Of Vascular Surgery 2017, 65: 1398-1406.e1. PMID: 28216356, DOI: 10.1016/j.jvs.2016.11.062.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplastyAsymptomatic DiseasesCarotid StenosisChi-Square DistributionDatabases, FactualDecision Support TechniquesEndarterectomy, CarotidFemaleHospital CostsHumansMaleMiddle AgedModels, EconomicPatient SelectionProcess Assessment, Health CarePropensity ScoreRetrospective StudiesStentsTime FactorsTreatment OutcomeUnited StatesConceptsCost of carotid artery stentingSymptomatic patientsHospital costsPropensity score matchingSymptomatic statusScore matchingPremier Perspective databaseCarotid artery stentingComorbidities of patientsStudent's t-testIn-hospital costsActual hospital costsAsymptomatic patientsSurgeon specialtyHospital characteristicsMale patientsCosts of carotid endarterectomyAsymptomatic cohortPerspective databaseArtery stentingPrimary outcomeCarotid endarterectomyPatientsClinical comorbiditiesHospital dischargeEndarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting
Arhuidese I, Nejim B, Chavali S, Locham S, Obeid T, Hicks C, Malas M. Endarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting. Journal Of Vascular Surgery 2017, 65: 1418-1428. PMID: 28190720, DOI: 10.1016/j.jvs.2016.11.041.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisChi-Square DistributionDatabases, FactualDisease-Free SurvivalEndarterectomy, CarotidFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient SelectionProportional Hazards ModelsRecurrenceRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeConceptsCohort of patientsCarotid endarterectomyIpsilateral CAIn-stent restenosisPerioperative stroke/deathAsymptomatic patientsMyocardial infarctionNo significant differenceVascular Quality Initiative (VQI) databaseTreatment of in-stent restenosisSignificant differenceComplication of carotid angioplastyCox regression analysisCompare carotid endarterectomyAdverse event ratesIncreased risk of strokeCarotid artery stentingOverall stroke rateRisk of strokeSymptomatic patientsIV statusPostoperative strokeCase seriesKaplan-MeierPatient characteristics
2016
Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients
Cooper M, Arhuidese I, Obeid T, Hicks C, Canner J, Malas M. Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients. JAMA Surgery 2016, 151: 947-952. PMID: 27366897, DOI: 10.1001/jamasurg.2016.1504.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAsymptomatic DiseasesDatabases, FactualEndarterectomy, CarotidFemaleHeart FailureHispanic or LatinoHumansKidney Failure, ChronicMaleMiddle AgedMobility LimitationMyocardial InfarctionPostoperative PeriodPulmonary Disease, Chronic ObstructiveRenal DialysisRetrospective StudiesRisk FactorsSex FactorsSmokingStrokeSurvival RateTime FactorsUnited StatesConceptsLong-term outcomesRisk of carotid endarterectomyAsymptomatic patientsLong-term strokeSymptomatic patientsCarotid endarterectomyDialysis patientsPerioperative strokeCohort of symptomatic patientsHistory of congestive heart failureMedian follow-up timePredictor of long-term mortalityMyocardial infarctionAssociated with poor outcomesDialysis-dependent patientsFollow-up timeOutcomes of carotid endarterectomyCox regression analysisCongestive heart failurePredictors of perioperative strokeLong-term mortalityChronic obstructive pulmonary diseaseDecrease stroke riskObstructive pulmonary diseasePatient-importantStenting versus endarterectomy after prior ipsilateral carotid endarterectomy
Arhuidese I, Obeid T, Nejim B, Locham S, Hicks C, Malas M. Stenting versus endarterectomy after prior ipsilateral carotid endarterectomy. Journal Of Vascular Surgery 2016, 65: 1-11. PMID: 27707617, DOI: 10.1016/j.jvs.2016.07.115.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisChi-Square DistributionCranial Nerve InjuriesDatabases, FactualEndarterectomy, CarotidFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient SelectionPropensity ScoreProportional Hazards ModelsRecurrenceReoperationRetrospective StudiesRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsIpsilateral CEACohort of patientsCarotid endarterectomyMyocardial infarctionPatient characteristicsOutcomes of carotid revascularizationVascular Quality Initiative (VQI) databaseSuperiority of carotid endarterectomyAssociated with high mortalityCranial nerve injuryIpsilateral carotid endarterectomyCompare patient characteristicsCox regression analysisRedo carotid endarterectomyIncreased risk of strokeAccess site complicationsPopulation-based studyPopulation-based evaluationRisk of strokeIpsilateral eventsAsymptomatic patientsSymptomatic patientsPeriprocedural periodPostoperative strokeCAS patientsCarotid Revascularization in Asymptomatic Patients after Renal Transplantation
Arhuidese I, Craig-Schapiro R, Obeid T, Nejim B, Hicks C, Malas M. Carotid Revascularization in Asymptomatic Patients after Renal Transplantation. Annals Of Vascular Surgery 2016, 38: 130-135. PMID: 27522968, DOI: 10.1016/j.avsg.2016.06.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid Artery DiseasesChi-Square DistributionEndarterectomy, CarotidFemaleHumansIncidenceKaplan-Meier EstimateKidney TransplantationLogistic ModelsMaleMiddle AgedMyocardial InfarctionOdds RatioPropensity ScoreProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsRenal transplant patientsCarotid artery stentingCox regression analysisTransplant patientsLong-term strokeCarotid endarterectomyCarotid revascularizationPerioperative strokeMyocardial infarctionRenal transplantationCarotid artery stenting cohortIncidence of perioperative complicationsCohort of renal transplant patientsChronic renal insufficiencyAssociated with increased riskAsymptomatic carotid artery stenosisRisk of periprocedural strokeRisk of perioperative strokeStroke-free survivalPropensity scoreSociety of Vascular SurgeryBaseline medical characteristicsUnited States Renal Data SystemBenefit of revascularizationCarotid artery stenosisPredictors of perioperative outcomes after carotid revascularization
Nejim B, Obeid T, Arhuidese I, Hicks C, Wang S, Canner J, Malas M. Predictors of perioperative outcomes after carotid revascularization. Journal Of Surgical Research 2016, 204: 267-273. PMID: 27565060, DOI: 10.1016/j.jss.2016.04.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCarotid ArteriesEndarterectomy, CarotidFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesStentsStrokeUnited StatesConceptsCarotid artery stentingPredictor of perioperative outcomesCarotid endarterectomyPerioperative outcomesAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databasePredictor of postoperative MIAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramQuality Improvement Program databaseSurgical Quality Improvement ProgramMultivariate logistic regression analysisRisk of postoperative strokeOdds of reoperationPredictors of reoperationOutcomes of carotid endarterectomyCongestive heart failurePerioperative outcomes of carotid endarterectomyChronic obstructive pulmonary diseaseAssociated with higher oddsLogistic regression analysisObstructive pulmonary diseasePrevalence of diabetes
2014
Surgeon’s 30-Day Outcomes Supporting the Carotid Revascularization Endarterectomy versus Stenting Trial
Grimm J, Arhuidese I, Beaulieu R, Qazi U, Perler B, Freischlag J, Malas M. Surgeon’s 30-Day Outcomes Supporting the Carotid Revascularization Endarterectomy versus Stenting Trial. JAMA Surgery 2014, 149: 1314-1318. PMID: 25391047, DOI: 10.1001/jamasurg.2014.1762.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisEndarterectomy, CarotidFemaleFollow-Up StudiesHumansMaleRetrospective StudiesStentsTreatment OutcomeConceptsComposite major adverse eventsCarotid Revascularization Endarterectomy Versus Stenting TrialCarotid artery stentingMajor adverse eventsAdverse eventsRisk of strokeCarotid endarterectomyMyocardial infarctionVascular surgeonsTreatment modalitiesHigh-risk patient characteristicsRisk of myocardial infarctionRetrospective analysis of patientsPeriprocedural risk of strokeComposite adverse eventsImprove patient selectionAnalysis of patientsRates of myocardial infarctionIncidence of perioperative strokeFisher's exact testPeriprocedural stroke rateCarotid Revascularization EndarterectomyNo significant differencePeriprocedural riskPatient selectionRisk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy
Hicks C, Talbott K, Canner J, Qazi U, Arhuidese I, Glebova N, Freischlag J, Perler B, Malas M. Risk of Disease Progression in Patients with Moderate Asymptomatic Carotid Artery Stenosis: Implications of Tobacco Use and Dual Antiplatelet Therapy. Annals Of Vascular Surgery 2014, 29: 1-8. PMID: 24530720, DOI: 10.1016/j.avsg.2014.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyAsymptomatic DiseasesBaltimoreCarotid StenosisChi-Square DistributionDisease ProgressionDrug Therapy, CombinationEndarterectomy, CarotidFemaleHumansIncidenceIschemic Attack, TransientLinear ModelsMaleMultivariate AnalysisPlatelet Aggregation InhibitorsPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexSmokingStentsStrokeTertiary Care CentersTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexConceptsProgression to severe stenosisAsymptomatic carotid artery stenosisDual antiplatelet therapyCarotid artery stenosisDisease progressionRisk factorsSevere stenosisIncidence of symptomsAntiplatelet therapyArtery stenosisPatient populationMean follow-up timeRisk of disease progressionSevere diseaseCox proportional hazards regression modelsRisk of progressionProportional hazards regression modelsFollow-up timeCarotid artery duplexAll-cause mortalityHazards regression modelsImproved medical therapyTransient ischemic attackTobacco useAsymptomatic carotid disease