2020
Safety of carotid artery revascularization procedures in patients with atrial fibrillation
Nejim B, Mathlouthi A, Weaver L, Faateh M, Arhuidese I, Malas M. Safety of carotid artery revascularization procedures in patients with atrial fibrillation. Journal Of Vascular Surgery 2020, 72: 2069-2078.e4. PMID: 32471737, DOI: 10.1016/j.jvs.2020.01.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCarotid Artery DiseasesCerebral HemorrhageCross-Sectional StudiesDatabases, FactualEndarterectomy, CarotidEndovascular ProceduresFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsCarotid artery stentingInternational Classification of DiseasesClinical Modification codesClassification of DiseasesOdds of intracerebral hemorrhagePredictors of ischemic strokeIntracerebral hemorrhageMultivariate logistic modelIn-hospital strokeCarotid artery diseaseCarotid endarterectomyHospital sizeAFib patientsInternational ClassificationModification codesHealthcare databasesMedication useStatistically significant predictorsAdjusted analysesAtrial fibrillationRandomized clinical trialsArtery diseasePremier Healthcare DatabaseAssociated with worse postoperative outcomesCarotid artery revascularization procedures
2017
Outcomes of Primary and Secondary Carotid Artery Stenting
Arhuidese I, Rizwan M, Nejim B, Malas M. Outcomes of Primary and Secondary Carotid Artery Stenting. Stroke 2017, 48: 3086-3092. PMID: 28974632, DOI: 10.1161/strokeaha.117.016963.Peer-Reviewed Original ResearchConceptsAssociated with significantly lower oddsSymptomatic patientsSignificantly lower oddsLower oddsIpsilateral carotid endarterectomyCox regression analysisOdds of hypotensionCarotid artery stentingVascular Quality InitiativeAsymptomatic patientsOdds of hypertensionKaplan-MeierPeriprocedural stroke/deathCAS proceduresPeriprocedural hypotensionArtery stentingCarotid angioplastyCarotid endarterectomyPatientsStroke/deathEvaluate outcomesOddsHypotensionBradycardiaStentCarotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy?
Nejim B, Aridi H, Locham S, Arhuidese I, Hicks C, Malas M. Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy? Journal Of Vascular Surgery 2017, 66: 1735-1748.e1. PMID: 28666824, DOI: 10.1016/j.jvs.2017.04.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarotid StenosisChi-Square DistributionEndarterectomy, CarotidEndovascular ProceduresFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProportional Hazards ModelsRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsTime FactorsTreatment OutcomeUnited StatesConceptsContralateral carotid artery occlusionCarotid artery occlusionCarotid artery stenting patientsCarotid artery stentingArtery occlusionCarotid endarterectomyRisk of strokeAsymptomatic patientsSymptomatic patientsHazard ratioOdds ratioHigh riskMultivariate logistic regression analysisContralateral carotid occlusionLog-rank testVascular Quality Initiative (VQI) registryCohort of patientsRisk of ipsilateral strokeCenters for MedicareShort-term outcomesCarotid artery revascularizationCarotid endarterectomy patientsHistory of strokeLogistic regression analysisCox proportional hazardsFixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study
Obeid T, Alshaikh H, Nejim B, Arhuidese I, Locham S, Malas M. Fixed and variable cost of carotid endarterectomy and stenting in the United States: A comparative study. Journal Of Vascular Surgery 2017, 65: 1398-1406.e1. PMID: 28216356, DOI: 10.1016/j.jvs.2016.11.062.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplastyAsymptomatic DiseasesCarotid StenosisChi-Square DistributionDatabases, FactualDecision Support TechniquesEndarterectomy, CarotidFemaleHospital CostsHumansMaleMiddle AgedModels, EconomicPatient SelectionProcess Assessment, Health CarePropensity ScoreRetrospective StudiesStentsTime FactorsTreatment OutcomeUnited StatesConceptsCost of carotid artery stentingSymptomatic patientsHospital costsPropensity score matchingSymptomatic statusScore matchingPremier Perspective databaseCarotid artery stentingComorbidities of patientsStudent's t-testIn-hospital costsActual hospital costsAsymptomatic patientsSurgeon specialtyHospital characteristicsMale patientsCosts of carotid endarterectomyAsymptomatic cohortPerspective databaseArtery stentingPrimary outcomeCarotid endarterectomyPatientsClinical comorbiditiesHospital dischargeEndarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting
Arhuidese I, Nejim B, Chavali S, Locham S, Obeid T, Hicks C, Malas M. Endarterectomy versus stenting in patients with prior ipsilateral carotid artery stenting. Journal Of Vascular Surgery 2017, 65: 1418-1428. PMID: 28190720, DOI: 10.1016/j.jvs.2016.11.041.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid StenosisChi-Square DistributionDatabases, FactualDisease-Free SurvivalEndarterectomy, CarotidFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient SelectionProportional Hazards ModelsRecurrenceRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeConceptsCohort of patientsCarotid endarterectomyIpsilateral CAIn-stent restenosisPerioperative stroke/deathAsymptomatic patientsMyocardial infarctionNo significant differenceVascular Quality Initiative (VQI) databaseTreatment of in-stent restenosisSignificant differenceComplication of carotid angioplastyCox regression analysisCompare carotid endarterectomyAdverse event ratesIncreased risk of strokeCarotid artery stentingOverall stroke rateRisk of strokeSymptomatic patientsIV statusPostoperative strokeCase seriesKaplan-MeierPatient characteristics
2016
Carotid Revascularization in Asymptomatic Patients after Renal Transplantation
Arhuidese I, Craig-Schapiro R, Obeid T, Nejim B, Hicks C, Malas M. Carotid Revascularization in Asymptomatic Patients after Renal Transplantation. Annals Of Vascular Surgery 2016, 38: 130-135. PMID: 27522968, DOI: 10.1016/j.avsg.2016.06.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplastyCarotid Artery DiseasesChi-Square DistributionEndarterectomy, CarotidFemaleHumansIncidenceKaplan-Meier EstimateKidney TransplantationLogistic ModelsMaleMiddle AgedMyocardial InfarctionOdds RatioPropensity ScoreProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsRenal transplant patientsCarotid artery stentingCox regression analysisTransplant patientsLong-term strokeCarotid endarterectomyCarotid revascularizationPerioperative strokeMyocardial infarctionRenal transplantationCarotid artery stenting cohortIncidence of perioperative complicationsCohort of renal transplant patientsChronic renal insufficiencyAssociated with increased riskAsymptomatic carotid artery stenosisRisk of periprocedural strokeRisk of perioperative strokeStroke-free survivalPropensity scoreSociety of Vascular SurgeryBaseline medical characteristicsUnited States Renal Data SystemBenefit of revascularizationCarotid artery stenosisSS22. Outcomes of Endarterectomy vs Stenting in Patients With Prior Ipsilateral Carotid Artery Stenting
Arhuidese I, Obeid T, Nejim B, Locham S, Hicks C, Malas M. SS22. Outcomes of Endarterectomy vs Stenting in Patients With Prior Ipsilateral Carotid Artery Stenting. Journal Of Vascular Surgery 2016, 63: 140s-141s. DOI: 10.1016/j.jvs.2016.03.243.Peer-Reviewed Original ResearchCarotid artery stentingArtery stentingPredictors of perioperative outcomes after carotid revascularization
Nejim B, Obeid T, Arhuidese I, Hicks C, Wang S, Canner J, Malas M. Predictors of perioperative outcomes after carotid revascularization. Journal Of Surgical Research 2016, 204: 267-273. PMID: 27565060, DOI: 10.1016/j.jss.2016.04.074.Peer-Reviewed Original ResearchConceptsCarotid artery stentingPredictor of perioperative outcomesCarotid endarterectomyPerioperative outcomesAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databasePredictor of postoperative MIAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramQuality Improvement Program databaseSurgical Quality Improvement ProgramMultivariate logistic regression analysisRisk of postoperative strokeOdds of reoperationPredictors of reoperationOutcomes of carotid endarterectomyCongestive heart failurePerioperative outcomes of carotid endarterectomyChronic obstructive pulmonary diseaseAssociated with higher oddsLogistic regression analysisObstructive pulmonary diseasePrevalence of diabetesOutcomes after carotid artery stenting in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Yin K, Canner J, Segev D, Malas M. Outcomes after carotid artery stenting in hemodialysis patients. Journal Of Vascular Surgery 2016, 63: 1511-1516. PMID: 27106247, DOI: 10.1016/j.jvs.2016.02.044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplastyCarotid Artery DiseasesChi-Square DistributionDatabases, FactualDisease-Free SurvivalFemaleHumansKidney DiseasesLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient SelectionProportional Hazards ModelsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsCarotid artery stentingHemodialysis patientsStudy of outcomesArtery stentingObservational study of outcomesCohort of hemodialysis patientsAsymptomatic dialysis patientsSingle-institution seriesMedian follow-upLong-term freedomPerceived poor outcomesLong-term outcomesPlanning carotid artery stentingLong-term survivalPopulation-based studyPredictors of strokeSymptomatic patientsPopulation-based study of outcomesPatient survivalRandomized studySymptomatic statusPoor outcomeFollow-upCox regressionDialysis patientsAbstract TMP21: Effect of Non-evidence Based Practices in Carotid Artery Stenting on Outcomes
Obeid T, Arhuidese I, Malas M. Abstract TMP21: Effect of Non-evidence Based Practices in Carotid Artery Stenting on Outcomes. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tmp21.Peer-Reviewed Original ResearchProximal embolic protectionPrimary stentingEmbolic protectionEffectiveness of primary stentingVascular Quality Initiative (VQI) databasePrimary composite end pointPrimary carotid stentingPrimary stent groupComposite end pointCarotid artery stentingOutcomes of CASMyocardial infarction ratePropensity score matchingAntagonist usePerioperative complicationsP2Y12 antagonistsStented patientsPatient-level factorsStroke/death rateTreated cohortLogistic regression modelsIpsilateral CEAStent groupArtery stentingCarotid stenting
2015
Beta-blocker use is associated with lower stroke and death after carotid artery stenting
Obeid T, Arhuidese I, Gaidry A, Qazi U, Abularrage C, Goodney P, Cronenwett J, Malas M. Beta-blocker use is associated with lower stroke and death after carotid artery stenting. Journal Of Vascular Surgery 2015, 63: 363-369. PMID: 26526052, PMCID: PMC5292260, DOI: 10.1016/j.jvs.2015.08.108.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenergic beta-AntagonistsAdultAgedAged, 80 and overAngioplastyCarotid Artery DiseasesChi-Square DistributionDatabases, FactualFemaleHemodynamicsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProtective FactorsRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsCarotid artery stentingBeta-blocker usePostprocedural hypertensionPostprocedural hypotensionBeta-blockersArtery stentingAssociated with postprocedural hypotensionEffect of preoperative medicationOutcomes of carotid artery stentingPredictors of postoperative strokeAssociated with lower strokeSelection of patientsMultivariate logistic regression modelDistal embolic protection useVascular Quality InitiativeMyocardial infarction rateGranular clinical dataMultiple controlled trialsPreoperative medicationsPostoperative strokeBeta blockersPeriprocedural stroke/deathStroke/death rateLogistic regression modelsStroke/death riskCarotid artery stent continued expansion days after deployment, without post stent deployment angioplasty
Qazi U, Obeid T, Arhuidese I, Malas M. Carotid artery stent continued expansion days after deployment, without post stent deployment angioplasty. Clinics And Practice 2015, 5: 767. PMID: 26664713, PMCID: PMC4653749, DOI: 10.4081/cp.2015.767.Peer-Reviewed Original ResearchCarotid artery stentingStent expansionPoststent ballooning is associated with increased periprocedural stroke and death rate in carotid artery stenting
Obeid T, Arnaoutakis D, Arhuidese I, Qazi U, Abularrage C, Black J, Perler B, Malas M. Poststent ballooning is associated with increased periprocedural stroke and death rate in carotid artery stenting. Journal Of Vascular Surgery 2015, 62: 616-623.e1. PMID: 26033011, DOI: 10.1016/j.jvs.2015.03.069.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplasty, BalloonCarotid StenosisChi-Square DistributionDatabases, FactualFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStentsStrokeTime FactorsTreatment OutcomeYoung AdultConceptsCarotid artery stentingCarotid endarterectomyHemodynamic depressionPerioperative strokeArtery stentingVascular Quality Initiative databaseApplication of carotid artery stentingAge of patientsIncreased perioperative riskIpsilateral CEASevere residual stenosisDeath rateCarotid artery lesionsLogistic regression analysisDegree of stenosisComplication rateSurgical riskPatient agePreoperative medicationsPerioperative riskRetrospective analysisSymptomatic statusIntraoperative techniquesResidual stenosisComparison to carotid endarterectomy
2014
Surgeon’s 30-Day Outcomes Supporting the Carotid Revascularization Endarterectomy versus Stenting Trial
Grimm J, Arhuidese I, Beaulieu R, Qazi U, Perler B, Freischlag J, Malas M. Surgeon’s 30-Day Outcomes Supporting the Carotid Revascularization Endarterectomy versus Stenting Trial. JAMA Surgery 2014, 149: 1314-1318. PMID: 25391047, DOI: 10.1001/jamasurg.2014.1762.Peer-Reviewed Original ResearchConceptsComposite major adverse eventsCarotid Revascularization Endarterectomy Versus Stenting TrialCarotid artery stentingMajor adverse eventsAdverse eventsRisk of strokeCarotid endarterectomyMyocardial infarctionVascular surgeonsTreatment modalitiesHigh-risk patient characteristicsRisk of myocardial infarctionRetrospective analysis of patientsPeriprocedural risk of strokeComposite adverse eventsImprove patient selectionAnalysis of patientsRates of myocardial infarctionIncidence of perioperative strokeFisher's exact testPeriprocedural stroke rateCarotid Revascularization EndarterectomyNo significant differencePeriprocedural riskPatient selection