2007
Expression of Bone Morphogenetic Proteins, the Subfamily of the Transforming Growth Factor-β Superfamily, in Renal Cell Carcinoma
Kwak C, Park Y, Kim I, Moon K, Ku J. Expression of Bone Morphogenetic Proteins, the Subfamily of the Transforming Growth Factor-β Superfamily, in Renal Cell Carcinoma. Journal Of Urology 2007, 178: 1062-1067. PMID: 17644140, DOI: 10.1016/j.juro.2007.05.005.Peer-Reviewed Original ResearchConceptsBone morphogenetic proteinBone morphogenetic protein 4Morphogenetic proteinsBone morphogenetic protein-7 expressionGrowth factor β superfamilyProtein-7 expressionTransforming Growth Factor-β SuperfamilyBone morphogenetic protein-4 expressionBone morphogenetic protein expressionProtein 4Largest subfamilyProtein expression rateCell typesProtein 4 expressionProteinProtein expressionSubfamiliesRenal cell carcinomaExpressionExpression rateSuperfamilyClear cell typePotential expressionCell carcinomaProtein immunoreactivity
2006
Role of bone morphogenetic proteins in transitional cell carcinoma cells
Kim I, Kim S. Role of bone morphogenetic proteins in transitional cell carcinoma cells. Cancer Letters 2006, 241: 118-123. PMID: 16500023, DOI: 10.1016/j.canlet.2005.10.009.Peer-Reviewed Original ResearchMeSH KeywordsBone Morphogenetic ProteinsCarcinoma, Transitional CellCell Line, TumorHumansSignal TransductionUrinary Bladder Neoplasms
2004
Restoration of Bone Morphogenetic Protein Receptor Type II Expression Leads to a Decreased Rate of Tumor Growth in Bladder Transitional Cell Carcinoma Cell Line TSU-Pr1
Kim I, Lee D, Lee D, Kim W, Kim M, Morton R, Lerner S, Kim S. Restoration of Bone Morphogenetic Protein Receptor Type II Expression Leads to a Decreased Rate of Tumor Growth in Bladder Transitional Cell Carcinoma Cell Line TSU-Pr1. Cancer Research 2004, 64: 7355-7360. PMID: 15492256, DOI: 10.1158/0008-5472.can-04-0154.Peer-Reviewed Original ResearchConceptsTSU-Pr1Cell line TSU-Pr1BMP-RIITumor growthBladder transitional cell carcinoma cellsHuman bladder cancer cell linesCell linesTransitional cell carcinoma cellsBladder cancer cell linesBone morphogenetic protein receptor type II (BMPR2) expressionBone morphogenetic proteinTSU-Pr1 cellsBladder TCC tissuesGrowth inhibitory effectsCancer cell linesBladder specimensType II expressionBladder TCCTumor gradeTransitional epitheliumClinical observationsTCC tissuesMalignant cellsSignificant associationBMP-RIA
2003
Decreased expression of bone morphogenetic protein (BMP) receptor type II correlates with insensitivity to BMP-6 in human renal cell carcinoma cells.
Kim I, Lee D, Lee D, Kim B, Kim H, Leach F, Linehan W, Morton R, Kim S. Decreased expression of bone morphogenetic protein (BMP) receptor type II correlates with insensitivity to BMP-6 in human renal cell carcinoma cells. Clinical Cancer Research 2003, 9: 6046-51. PMID: 14676131.Peer-Reviewed Original ResearchBlotting, NorthernBone Morphogenetic Protein 6Bone Morphogenetic Protein Receptors, Type IIBone Morphogenetic ProteinsCarcinoma, Renal CellDown-RegulationHumansImmunoblottingImmunoenzyme TechniquesKidney NeoplasmsProtein Serine-Threonine KinasesReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionTransforming Growth Factor betaTumor Cells, Cultured