Loss of expression of transforming growth factor-beta receptors is associated with poor prognosis in prostate cancer patients.
Kim I, Ahn H, Lang S, Oefelein M, Oyasu R, Kozlowski J, Lee C. Loss of expression of transforming growth factor-beta receptors is associated with poor prognosis in prostate cancer patients. Clinical Cancer Research 1998, 4: 1625-30. PMID: 9676836.Peer-Reviewed Original ResearchConceptsHuman prostate cancer tissuesClinical tumor stageProstate cancer patientsProstate cancer tissuesGleason scoreLoss of expressionTGF-betaRIRecurrence rateTumor stageCancer patientsRadical prostatectomyCancer tissuesSurvival rateSignificant associationPotential prognostic valuePotential prognostic markerReceptor type IGrowth factor betaGrowth factor beta receptorTGF-beta receptorsInitial diagnosisPoor prognosisPrognostic valueDisease progressionPrognostic marker