2020
RNA-seq profile of African American men with a clinically localized prostate cancer
Nagaya N, Rosenfeld J, Lee G, Kim I. RNA-seq profile of African American men with a clinically localized prostate cancer. Prostate International 2020, 9: 125-131. PMID: 34692584, PMCID: PMC8498718, DOI: 10.1016/j.prnil.2020.11.002.Peer-Reviewed Original ResearchProstate cancer tissuesProstate cancerAfrican American menAA menCA menCancer tissuesPotential genetic risk factorSphingosine-1-phosphate signalingAmerican menExpression levelsGenetic risk factorsIngenuity Pathway AnalysisPathway analysisRNA sequencingPoor prognosisBiochemical recurrenceRadical prostatectomyRisk factorsLow expressionCancerMenCaucasiansSignificant differencesPatientsHigh rate
2018
Multi-institution analysis of racial disparity among African-American men eligible for prostate cancer active surveillance
Dinizo M, Shih W, Kwon Y, Eun D, Reese A, Giusto L, Trabulsi E, Yuh B, Ruel N, Marchalik D, Hwang J, Kundu S, Eggener S, Kim I. Multi-institution analysis of racial disparity among African-American men eligible for prostate cancer active surveillance. Oncotarget 2018, 9: 21359-21365. PMID: 29765545, PMCID: PMC5940363, DOI: 10.18632/oncotarget.25103.Peer-Reviewed Original ResearchLow-risk prostate cancerProstate cancerWhite American menActive surveillanceAfrican American menRacial disparitiesRadical prostatectomyProstate cancer active surveillanceActive surveillance eligibilityMulti-institution databaseRisk prostate cancerUnderwent radical prostatectomyActive surveillance criteriaPositive surgical marginsTertiary care institutionSingle-institution studyMulti-institution analysisPotential racial disparitiesSignificant racial disparitiesPercentage cancerOncologic outcomesSurgical marginsHigher BMIProspective studyCancer outcomes
2013
Increased Incidence of Pathologically Nonorgan Confined Prostate Cancer in African-American Men Eligible for Active Surveillance
Ha Y, Salmasi A, Karellas M, Singer E, Kim J, Han M, Partin A, Kim W, Lee D, Kim I. Increased Incidence of Pathologically Nonorgan Confined Prostate Cancer in African-American Men Eligible for Active Surveillance. Urology 2013, 81: 831-836. PMID: 23465143, PMCID: PMC3978180, DOI: 10.1016/j.urology.2012.12.046.Peer-Reviewed Original ResearchConceptsNational Comprehensive Cancer NetworkAA menRadical prostatectomyActive surveillanceProstate cancerNCCN criteriaBiopsy coresAS criteriaAS inclusion criteriaFinal surgical pathologyComprehensive Cancer NetworkPositive biopsy coresDatabase of menWorse clinicopathological featuresAfrican American menPathological upstagingAdvanced diseaseIndependent predictorsPathologic characteristicsClinicopathological featuresPreoperative PSAClinicopathologic findingsWA patientsInclusion criteriaPositive cores
2012
Risk of more advanced cancer at surgery in African American men eligible for active surveillance.
Salmasi A, Han M, Kim I. Risk of more advanced cancer at surgery in African American men eligible for active surveillance. Journal Of Clinical Oncology 2012, 30: e15214-e15214. DOI: 10.1200/jco.2012.30.15_suppl.e15214.Peer-Reviewed Original ResearchActive surveillanceAdvanced cancerRadical prostatectomyProstate cancerNational Cancer InstituteAA menAfrican American menCaucasian manHigh riskCancer InstituteFavorable-risk prostate cancerPre-operative PSA levelLow-grade prostate cancerUnderwent radical prostatectomyRisk prostate cancerGrade prostate cancerJohns Hopkins Medical InstitutionsNCI criteriaPreoperative predictorsPSA levelsGrading of PCaPathological characteristicsSV involvementInclusion criteriaPositive cores