1994
Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients
Petzelbauer P, Pober J, Keh A, Braverman I. Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients. Journal Of Investigative Dermatology 1994, 103: 300-305. PMID: 7521374, DOI: 10.1111/1523-1747.ep12394720.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Endothelial leukocyte adhesion molecule-1Lesional skinAdhesion molecule-1Psoriatic patientsEndothelial cellsUninvolved skinPerilesional skinMolecule-1Dermal microvasculatureCapillary loopsCell adhesion molecule-1Perivascular inflammatory infiltratesLeukocyte adhesion molecule-1VCAM-1 expressionTumor necrosis factorEndothelial adhesion moleculesMicrovascular endothelial cellsEndothelial cell expressionVenular endothelial cellsInflammatory infiltrateEpidermal involvementPsoriatic plaquesSuperficial plexusNecrosis factor
1991
The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis
Verga M, Braverman I. The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis. JAMA Dermatology 1991, 127: 1503-1510. PMID: 1929457, DOI: 10.1001/archderm.1991.01680090067006.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaT-cell lymphomaCTCL lesionsImmunohistologic analysisEarly-stage cutaneous T-cell lymphomaBenign inflammatory diseaseImmunohistologic patternsDR antibodiesHLA-DRBiopsy specimensInflammatory diseasesPsoriatic lesionsImmunoperoxidase techniquePsoriatic skinDermatitic lesionsExtensive stainingPsoriasisNormal skinDermatitisLesionsPatientsMonoclonal antibodiesEpidermal areaLymphomaAntibodies
1990
Correlation of Laser Doppler Wave Patterns with Underlying Microvascular Anatomy
Braverman I, Keh A, Goldminz D. Correlation of Laser Doppler Wave Patterns with Underlying Microvascular Anatomy. Journal Of Investigative Dermatology 1990, 95: 283-286. PMID: 2143522, DOI: 10.1111/1523-1747.ep12484917.Peer-Reviewed Original Research
1989
Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesionsUltrastructure and organization of the cutaneous microvasculature in normal and pathologic states.
Braverman I. Ultrastructure and organization of the cutaneous microvasculature in normal and pathologic states. Journal Of Investigative Dermatology 1989, 93: 2s-9s. PMID: 2666519, DOI: 10.1111/1523-1747.ep12580893.Peer-Reviewed Original ResearchUltrastructure and Organization of the Cutaneous Microvasculature in Normal and Pathologic States
Braverman I. Ultrastructure and Organization of the Cutaneous Microvasculature in Normal and Pathologic States. Journal Of Investigative Dermatology 1989, 93: s2-s9. DOI: 10.1038/jid.1989.2.Peer-Reviewed Original Research
1986
Three-Dimensional Reconstruction of Endothelial Cell Gaps in Psoriatic Vessels and Their Morphologic Identity with Gaps Produced by the Intradermal Injections of Histamine
Braverman I, Keh-Yen A. Three-Dimensional Reconstruction of Endothelial Cell Gaps in Psoriatic Vessels and Their Morphologic Identity with Gaps Produced by the Intradermal Injections of Histamine. Journal Of Investigative Dermatology 1986, 86: 577-581. PMID: 3745967, DOI: 10.1111/1523-1747.ep12355222.Peer-Reviewed Original Research
1985
The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate
Braverman I, Sibley J. The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate. Journal Of Investigative Dermatology 1985, 85: 584-586. PMID: 4067330, DOI: 10.1111/1523-1747.ep12283604.Peer-Reviewed Original ResearchConceptsOral methotrexateTopical steroidsLabeling indexPsoriatic epidermisInitial clinical improvementPlastic wrap occlusionTopical steroid therapyBasal cellsLack of responseGoeckerman treatmentSteroid therapyClinical relapseClinical improvementPsoriatic patientsPsoriatic plaquesSuccessful therapyDermal capillariesCapillary ultrastructureMethotrexateModerate acanthosisCapillary loopsSteroidsDermal papillaTherapyMicrovessels
1983
The role of blood vessels and lymphatics in cutaneous inflammatory processes: an overview.
Braverman I. The role of blood vessels and lymphatics in cutaneous inflammatory processes: an overview. British Journal Of Dermatology 1983, 109 Suppl 25: 89-98. PMID: 6344912.Peer-Reviewed Original Research
1982
Studies in Cutaneous Aging II. The Microvasculature
Braverman I, Fonferko E. Studies in Cutaneous Aging II. The Microvasculature. Journal Of Investigative Dermatology 1982, 78: 444-448. PMID: 7069222, DOI: 10.1111/1523-1747.ep12508027.Peer-Reviewed Original ResearchConceptsVeil cellsBasement membrane-like materialButtock skinVascular wallMicrocirculatory vesselsMembrane-like materialVascular wall thickeningThin-walled vesselsDiabetes mellitusAging IIActinic damagePsoriatic individualsIndividuals 80Chronological agingPostcapillary venulesWall thickeningPeripheral portionVenous capillariesProgressive agingSkinRough endoplasmic reticulumEarly phaseWalled vesselsVesselsCellsStudies in Cutaneous Aging: I. The Elastic Fiber Network
Braverman I, Fonferko E. Studies in Cutaneous Aging: I. The Elastic Fiber Network. Journal Of Investigative Dermatology 1982, 78: 434-443. PMID: 7069221, DOI: 10.1111/1523-1747.ep12507866.Peer-Reviewed Original ResearchConceptsButtock skinActinic damageCutaneous agingElastic fibersElastic fiber degradationInflammatory cellsAge 50Age 70Psoriatic individualsChronological agingAge 30Young adultsPorcine pancreatic elastaseAbnormalitiesSkinPancreatic elastaseElastaseElastic fiber networkDifferent agesAgingMorphological evidenceDamageRole of the Microcirculation in the Treatment and Pathogenesis of Psoriasis
Braverman I, Sibley J. Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis. Journal Of Investigative Dermatology 1982, 78: 12-17. PMID: 7054305, DOI: 10.1111/1523-1747.ep12497850.Peer-Reviewed Original ResearchConceptsLabeling indexCapillary loopsButtock skinPathogenesis of psoriasisNormal labeling indexUntreated patientsPsoriatic patientsPUVA treatmentSerial biopsiesVascular proliferationEpidermal hyperplasiaAbnormal capillariesPatientsPsoriasisBasal cellsCapillary growthIndividual plaquesArterial capillariesBiopsyTreatmentSkinIdentical methodsDay intervalsPsoriaticsCapillaries
1977
ULTRASTRUCTURE OF THE CAPILLARY LOOPS IN THE DERMAL PAPILLAE OF PSORIASIS
Braverman I, Yen A. ULTRASTRUCTURE OF THE CAPILLARY LOOPS IN THE DERMAL PAPILLAE OF PSORIASIS. Journal Of Investigative Dermatology 1977, 68: 53-60. PMID: 830771, DOI: 10.1111/1523-1747.ep12485169.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyCapillariesCell MovementCoal TarHumansNeutrophilsPsoriasisSkinUltraviolet TherapyConceptsCapillary loopsPustular psoriasisPsoriasis vulgarisInitiation of therapyVenous capillariesDermal papillaVon ZumbuschGoeckerman regimenGoeckerman therapyPsoriatic lesionsNormal skinPsoriasisIntrapapillary portionArterial capillariesPlastic-embedded sectionsTherapyUltrastructural differencesPapillaeLoop patternULTRASTRUCTURE OF THE HUMAN DERMAL MICROCIRCULATION
Braverman I, Yen A. ULTRASTRUCTURE OF THE HUMAN DERMAL MICROCIRCULATION. Journal Of Investigative Dermatology 1977, 68: 44-52. PMID: 830769, DOI: 10.1111/1523-1747.ep12485165.Peer-Reviewed Original ResearchConceptsCapillary loopsVenous characteristicsNormal skinBasement membraneHuman Dermal MicrocirculationArterial capillariesIntrapapillary capillary loopsNummular eczemaVascular abnormalitiesArterial loopPsoriatic skinNormal forearmsUpper dermisDermal plexusDermal microcirculationIntrapapillary portionVenous capillariesFenestration
1974
Microcirculation in Psoriatic Skin
Braverman I, Yen A. Microcirculation in Psoriatic Skin. Journal Of Investigative Dermatology 1974, 62: 493-502. PMID: 4823589, DOI: 10.1111/1523-1747.ep12681007.Peer-Reviewed Original Research
1972
Electron Microscopic Studies of the Microcirculation in Psoriasis
Braverman I. Electron Microscopic Studies of the Microcirculation in Psoriasis. Journal Of Investigative Dermatology 1972, 59: 91-98. PMID: 5039967, DOI: 10.1111/1523-1747.ep12625852.Peer-Reviewed Original ResearchConceptsThin-walled vesselsPost-capillary venulesEndothelial cell gapsBlood cellsWalled vesselsVon ZumbuschPustular psoriasisRed blood cellsVascular findingsPsoriasis vulgarisUninvolved skinPsoriatic lesionsAbsence of pericytesChemical mediatorsPsoriasisElectron microscopic studyIdentical findingsMicrocirculationConsistent findingPermeable vesselsUpper thirdDermal papillaBasal laminaLesionsVenulesMetabolic and Ultrastructural Studies in a Patient With Pustular Psoriasis (von Zumbusch)
Braverman I, Cohen I, O'Keefe E. Metabolic and Ultrastructural Studies in a Patient With Pustular Psoriasis (von Zumbusch). JAMA Dermatology 1972, 105: 189-196. PMID: 4334267, DOI: 10.1001/archderm.1972.01620050003001.Peer-Reviewed Original ResearchConceptsChronic hypoalbuminemiaPustular psoriasisClinical Research CenterPersistent hypocalcemiaUninvolved skinAbnormal vesselsElectron microscopic examinationSkin lesionsWhite womenPatientsEndothelial cellsEndothelial wallMicroscopic examinationHypoalbuminemiaUltrastructural studyPsoriasisCapillary segmentsSerum albuminVesselsHypocalcemiaLesionsMicrocirculationAbnormalitiesMonthsWomen
1962
Psoriasis, Lupus Erythematosus, and Pityriasis Rubra Pilaris: Occurrence in One Family
LERNER M, BRAVERMAN I. Psoriasis, Lupus Erythematosus, and Pityriasis Rubra Pilaris: Occurrence in One Family. JAMA Dermatology 1962, 85: 229-231. PMID: 14464250, DOI: 10.1001/archderm.1962.01590020069008.Peer-Reviewed Original ResearchConceptsPityriasis rubra pilarisLupus erythematosusDermatology outpatient clinicDiscoid lupus erythematosusYale-New Haven Medical CenterCASES Case 1Typical psoriasisFirst patientOutpatient clinicMedical CenterSkin diseasesPsoriasisCase 1Second childFirst childErythematosusDermatitisPilarisChildrenBoys