1994
Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients
Petzelbauer P, Pober J, Keh A, Braverman I. Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients. Journal Of Investigative Dermatology 1994, 103: 300-305. PMID: 7521374, DOI: 10.1111/1523-1747.ep12394720.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Endothelial leukocyte adhesion molecule-1Lesional skinAdhesion molecule-1Psoriatic patientsEndothelial cellsUninvolved skinPerilesional skinMolecule-1Dermal microvasculatureCapillary loopsCell adhesion molecule-1Perivascular inflammatory infiltratesLeukocyte adhesion molecule-1VCAM-1 expressionTumor necrosis factorEndothelial adhesion moleculesMicrovascular endothelial cellsEndothelial cell expressionVenular endothelial cellsInflammatory infiltrateEpidermal involvementPsoriatic plaquesSuperficial plexusNecrosis factor
1989
Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesions
1985
The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate
Braverman I, Sibley J. The Response of Psoriatic Epidermis and Microvessels to Treatment with Topical Steroids and Oral Methotrexate. Journal Of Investigative Dermatology 1985, 85: 584-586. PMID: 4067330, DOI: 10.1111/1523-1747.ep12283604.Peer-Reviewed Original ResearchConceptsOral methotrexateTopical steroidsLabeling indexPsoriatic epidermisInitial clinical improvementPlastic wrap occlusionTopical steroid therapyBasal cellsLack of responseGoeckerman treatmentSteroid therapyClinical relapseClinical improvementPsoriatic patientsPsoriatic plaquesSuccessful therapyDermal capillariesCapillary ultrastructureMethotrexateModerate acanthosisCapillary loopsSteroidsDermal papillaTherapyMicrovessels
1982
Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis
Braverman I, Sibley J. Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis. Journal Of Investigative Dermatology 1982, 78: 12-17. PMID: 7054305, DOI: 10.1111/1523-1747.ep12497850.Peer-Reviewed Original ResearchConceptsLabeling indexCapillary loopsButtock skinPathogenesis of psoriasisNormal labeling indexUntreated patientsPsoriatic patientsPUVA treatmentSerial biopsiesVascular proliferationEpidermal hyperplasiaAbnormal capillariesPatientsPsoriasisBasal cellsCapillary growthIndividual plaquesArterial capillariesBiopsyTreatmentSkinIdentical methodsDay intervalsPsoriaticsCapillaries