1996
Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma
Wilson L, Quiros P, Kolenik S, Heald P, Braverman I, Edelson R, Kacinski B. Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma. Journal Of The American Academy Of Dermatology 1996, 35: 69-73. PMID: 8682967, DOI: 10.1016/s0190-9622(96)90499-5.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaRecurrent cutaneous T-cell lymphomaComplete responseT-cell lymphomaElectron beam therapySecond courseMedian disease-free intervalThird courseAdditional coursesBeam therapyDisease-free intervalTreatment of patientsAcceptable risk profileForm of therapyMedian doseMedian survivalMild erythemaPatientsInitial courseTherapyVariety of modalitiesRisk profileEntire groupLocalized radiation2159 Total skin electron beam therapy(TSEBT) followed by adjuvant psoralen/ultraviolet A light (PUVA) in the management of patients with T1 and T2 cutaneous T-cell lymphoma (CTCL)
Quiros P, Kacinski B, Heald P, Edelson R, Braverman I, Wilson L. 2159 Total skin electron beam therapy(TSEBT) followed by adjuvant psoralen/ultraviolet A light (PUVA) in the management of patients with T1 and T2 cutaneous T-cell lymphoma (CTCL). International Journal Of Radiation Oncology • Biology • Physics 1996, 36: 355. DOI: 10.1016/s0360-3016(97)85733-1.Peer-Reviewed Original Research
1995
Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases
Lambroza E, Cohen S, Phelps R, Lebwohl M, Braverman I, DiCostanzo D. Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases. Journal Of The American Academy Of Dermatology 1995, 32: 987-993. PMID: 7751470, DOI: 10.1016/0190-9622(95)91337-8.Peer-Reviewed Original ResearchConceptsMycosis fungoidesEpidermal atrophyVariant of MFTreatment of choiceMedian ageMononuclear cellsHistologic findingsBiopsy diagnosisComplete repigmentationDisease onsetTreatment outcomesMF variantDisease processNew casesYoung populationPrior reportsFungoidesPUVAPatientsAtrophyMicroscopic featuresHistopathologyTreatmentDark skinSkinMalignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation.
Licata AG, Wilson LD, Braverman IM, Feldman AM, Kacinski BM. Malignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation. JAMA Dermatology 1995, 131: 432-5. PMID: 7726585, DOI: 10.1001/archderm.131.4.432.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaT-cell lymphomaSquamous cell carcinomaBasal cell carcinomaElectron beam therapyAdditional radiation therapyCell carcinomaCutaneous malignanciesOral psoralenAdditional therapyMalignant melanomaRadiation therapyBeam therapyTotal skin electron beam radiationFurther radiation therapyGroup of patientsNonmelanoma skin cancerAnecdotal case reportsPrevious large studiesTopical mechlorethamineHydrochloride therapyCase reportPatientsCarcinomaMalignant Melanoma and Other Second Cutaneous Malignancies in Cutaneous T-Cell Lymphoma: The Influence of Additional Therapy After Total Skin Electron Beam Radiation
Licata A, Wilson L, Braverman I, Feldman A, Kacinski B. Malignant Melanoma and Other Second Cutaneous Malignancies in Cutaneous T-Cell Lymphoma: The Influence of Additional Therapy After Total Skin Electron Beam Radiation. JAMA Dermatology 1995, 131: 432-435. DOI: 10.1001/archderm.1995.01690160060009.Peer-Reviewed Original ResearchTotal skin electron beam therapyCutaneous T-cell lymphomaT-cell lymphomaSquamous cell carcinomaBasal cell carcinomaElectron beam therapyAdditional radiation therapyCell carcinomaCutaneous malignanciesOral psoralenAdditional therapyMalignant melanomaRadiation therapyBeam therapyTotal skin electron beam radiationFurther radiation therapyGroup of patientsNonmelanoma skin cancerAnecdotal case reportsPrevious large studiesTopical mechlorethamineHydrochloride therapyCase reportPatientsCarcinoma
1994
Novel prognostic factors predictive of prolonged relapse-free and overall survival in advanced stage CTCL (mycosis fungoides) patients treated with total skin electron beam therapy
Kacinski B, Wilson L, Quiros P, Kolenik S, Heald P, Edelson R, Braverman I. Novel prognostic factors predictive of prolonged relapse-free and overall survival in advanced stage CTCL (mycosis fungoides) patients treated with total skin electron beam therapy. International Journal Of Radiation Oncology • Biology • Physics 1994, 30: 268. DOI: 10.1016/0360-3016(94)90823-0.Peer-Reviewed Original ResearchAdditional courses of total skin electron beam therapy [TSEBT] in the retreatment of patients with cutaneous t-cell lymphoma [CTCL]
Wilson L, Quiros P, Kolenik S, Heald P, Braverman I, Edelson R, Kacinski B. Additional courses of total skin electron beam therapy [TSEBT] in the retreatment of patients with cutaneous t-cell lymphoma [CTCL]. International Journal Of Radiation Oncology • Biology • Physics 1994, 30: 269. DOI: 10.1016/0360-3016(94)90825-7.Peer-Reviewed Original Research
1993
Adjuvant Extracorporeal Photoimmunotherapy or adjuvant adriamyciwcytoxan chemotherapy both prolong survival for cutaneous T-cell lymphoma (CTCL, MYCOSIS FUNGOIDES) patients treated with total skin electron beam therapy (TSEBT).
Kacinaki B, Wilson L, Goodrich A, Edelson R, Heald P, Braverman I. Adjuvant Extracorporeal Photoimmunotherapy or adjuvant adriamyciwcytoxan chemotherapy both prolong survival for cutaneous T-cell lymphoma (CTCL, MYCOSIS FUNGOIDES) patients treated with total skin electron beam therapy (TSEBT). International Journal Of Radiation Oncology • Biology • Physics 1993, 27: 186-187. DOI: 10.1016/0360-3016(93)90727-d.Peer-Reviewed Original Research
1992
Pseudoxanthoma-elasticum-Like Skin Changes Induced by Penicillamine
Bolognia J, Braverman I. Pseudoxanthoma-elasticum-Like Skin Changes Induced by Penicillamine. Dermatology 1992, 184: 12-18. PMID: 1558988, DOI: 10.1159/000247491.Peer-Reviewed Case Reports and Technical NotesConceptsAnterior axillary lineLong-term therapyRedundant skin foldsDermal elastic fibersFlexural areasHemorrhagic blistersLike lesionsSkin changesUninvolved skinYellow papulesAxillary lineHistologic changesLower buttockSkin lesionsSkin foldsPseudoxanthoma elasticumWilson's diseasePatientsLesionsSkin appearanceCalcium depositionPenicillamineElastic fibersDiseaseCystinuriaThe role of novel prognostic factors & adjuvant therapy in CTCL (Mycosis fungoides) patients treated with total skin electron beam therapy
Kacinski B, Murren J, Friedman N, Braverman I, Cooper D. The role of novel prognostic factors & adjuvant therapy in CTCL (Mycosis fungoides) patients treated with total skin electron beam therapy. International Journal Of Radiation Oncology • Biology • Physics 1992, 24: 229. DOI: 10.1016/0360-3016(92)90308-5.Peer-Reviewed Original Research
1991
The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis
Verga M, Braverman I. The Use of Immunohistologic Analysis in Differentiating Cutaneous T-cell Lymphoma From Psoriasis and Dermatitis. JAMA Dermatology 1991, 127: 1503-1510. PMID: 1929457, DOI: 10.1001/archderm.1991.01680090067006.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaT-cell lymphomaCTCL lesionsImmunohistologic analysisEarly-stage cutaneous T-cell lymphomaBenign inflammatory diseaseImmunohistologic patternsDR antibodiesHLA-DRBiopsy specimensInflammatory diseasesPsoriatic lesionsImmunoperoxidase techniquePsoriatic skinDermatitic lesionsExtensive stainingPsoriasisNormal skinDermatitisLesionsPatientsMonoclonal antibodiesEpidermal areaLymphomaAntibodiesRepeat courses of either total skin electron beam therapy (TSEBT) or local RT are safe and effective palliation to relapsed CTCL patients whose symptoms are not controlled by other topical or systemic anti-ctcl therapies
Kacinski B, Friedrtan N, Murren J, Cooper D, Braverman I. Repeat courses of either total skin electron beam therapy (TSEBT) or local RT are safe and effective palliation to relapsed CTCL patients whose symptoms are not controlled by other topical or systemic anti-ctcl therapies. International Journal Of Radiation Oncology • Biology • Physics 1991, 21: 212. DOI: 10.1016/0360-3016(91)90608-7.Peer-Reviewed Original Research
1989
Skin changes in menopause
Bolognia J, Braverman I, Rousseau M, Sarrel P. Skin changes in menopause. Maturitas 1989, 11: 295-304. PMID: 2693917, DOI: 10.1016/0378-5122(89)90026-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMenopausal womenEstrogen replacement therapyElastic fibersAge-related ultrastructural changesSun-exposed skinSun-protected skinDermal elastic fibersCutaneous signsEstrogen deprivationPremature menopauseReplacement therapySkin changesSkin signsTreatment periodCystic spacesDegenerative changesGranular degenerationSymptomsUltrastructural changesWomenMenopauseSignificant differencesPatientsPremature agingSkinAngiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesionsElastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Clinics In Geriatric Medicine 1989, 5: 69-90. PMID: 2646003, DOI: 10.1016/s0749-0690(18)30696-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesClinical featuresDiabetic patientsVeil cellsJuvenile diabetesDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processLikely correlateDiabetesPatientsAtrophy
1987
Combined total body electron beam irradiation and chemotherapy for mycosis fungoides
Braverman I, Yager N, Chen M, Cadman E, Hait W, Maynard T. Combined total body electron beam irradiation and chemotherapy for mycosis fungoides. Journal Of The American Academy Of Dermatology 1987, 16: 45-60. PMID: 3100583, DOI: 10.1016/s0190-9622(87)70004-8.Peer-Reviewed Original ResearchConceptsComplete clinical remissionElectron beam therapyMycosis fungoidesClinical remissionBeam therapyKaplan-Meier methodElevated blood levelsSignificant differencesGeneralized Wilcoxon testSézary cellsCombination therapyBlood levelsControl subjectsActuarial analysisStage IStage IIIPatientsFungoidesTherapyKaryotypic abnormalitiesMonthly cyclesWilcoxon testRemissionChemotherapyStatistical analysisElectron microscopic and immunolabeling studies of the lesional and normal skin of patients with mycosis fungoides treated by total body electron beam irradiation
Braverman I, Klein S, Grant A. Electron microscopic and immunolabeling studies of the lesional and normal skin of patients with mycosis fungoides treated by total body electron beam irradiation. Journal Of The American Academy Of Dermatology 1987, 16: 61-74. PMID: 3100584, DOI: 10.1016/s0190-9622(87)70005-x.Peer-Reviewed Original ResearchConceptsEpidermal Langerhans cellsElectron beam therapyLangerhans cellsMycosis fungoidesIndeterminate cellsNormal skinDisease courseLesional skinBeam therapySkin lesionsNonspecific skin lesionsPatient's disease courseIa-positive cellsEpidermal cell suspensionsEpidermal thymocyteClinical remissionBiopsy specimensPretreatment levelsIa antigensFungoidesTherapyLesionsSkinPatientsCells
1986
Elastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Dermatologic Clinics 1986, 4: 391-405. PMID: 3521985, DOI: 10.1016/s0733-8635(18)30802-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesDiabetic patientsJuvenile diabeticsClinical featuresVeil cellsDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processDiabeticsLikely correlatePatientsAtrophy
1983
Classification and Therapy of Atrophie Blanche
Milstone L, Braverman I, Lucky P, Fleckman P. Classification and Therapy of Atrophie Blanche. JAMA Dermatology 1983, 119: 963-969. PMID: 6651312, DOI: 10.1001/archderm.1983.01650360009005.Peer-Reviewed Original ResearchConceptsAtrophie blancheCommon pathologic eventEndogenous fibrinolytic activityCharacteristic histopathologic featuresPlatelet thrombus formationOcclusion of vesselsMost patientsClinical evolutionHistopathologic featuresPurpuric papulesClinicopathologic entityLower extremitiesPathologic eventsDeep dermisThrombus formationFibrinolytic activityMultiple causesTherapyTreatmentCauseUlcerationPatientsPapulesPathogenesisDisease
1982
Commentary: Migratory Necrolytic Erythema
Braverman I. Commentary: Migratory Necrolytic Erythema. JAMA Dermatology 1982, 118: 796-798. DOI: 10.1001/archderm.1982.01650220100012.Peer-Reviewed Original Research