Featured Publications
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data
Gaudino M, Di Franco A, Alexander JH, Bakaeen F, Egorova N, Kurlansky P, Boening A, Chikwe J, Demetres M, Devereaux PJ, Diegeler A, Dimagli A, Flather M, Hameed I, Lamy A, Lawton JS, Reents W, Robinson NB, Audisio K, Rahouma M, Serruys PW, Hara H, Taggart DP, Girardi LN, Fremes SE, Benedetto U. Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal 2021, 43: 18-28. PMID: 34338767, PMCID: PMC8851663, DOI: 10.1093/eurheartj/ehab504.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassCoronary Artery DiseaseFemaleHumansMaleMyocardial InfarctionPercutaneous Coronary InterventionSex CharacteristicsStrokeTreatment OutcomeConceptsCoronary artery bypassIndividual patient dataMyocardial infarctionArtery bypassCause mortalityWorse outcomesMultiple arterial graftingPatient dataOff-pump surgeryOutcomes of womenCABG trialBaseline characteristicsPatients 75Secondary outcomesPrimary outcomeArterial graftingCox regressionPooled analysisSurgical techniqueHigh riskHigh incidenceSimilar mortalitySystematic reviewRisk adjustmentMortalitySystematic Assessment of Online Health Information for Coronary Revascularization
Hameed I, Hameed NUF, Oakley CT, Gambardella I, Bravo C, Angiolillo DJ, Gaudino M. Systematic Assessment of Online Health Information for Coronary Revascularization. JAMA Internal Medicine 2021, 181: 1003-1006. PMID: 33871563, PMCID: PMC8056308, DOI: 10.1001/jamainternmed.2021.1051.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassCoronary Artery DiseaseHumansMyocardial RevascularizationPatient Education as TopicPercutaneous Coronary InterventionTreatment Outcome
2021
The impact of trainees' working hour regulations on outcome in CABG and valve surgery in the State of New York
Amabile A, Mori M, Brooks C, Weininger G, Shang M, Fereydooni S, Komlo CM, Mullan CW, Hameed I, Geirsson A. The impact of trainees' working hour regulations on outcome in CABG and valve surgery in the State of New York. Journal Of Cardiac Surgery 2021, 36: 4582-4590. PMID: 34617327, DOI: 10.1111/jocs.16058.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassEducation, Medical, GraduateHumansInternship and ResidencyNew YorkPersonnel Staffing and SchedulingConceptsShort-term outcomesRisk-adjusted mortality ratesDuty hour regulationsTeaching hospitalBetter short-term outcomesWorse short-term outcomesCoronary artery bypassDuty hour policiesOverall surgical volumeArtery bypassCABG surgeryValve surgeryCABG proceduresCardiac surgeryValve proceduresSurgical volumeFirst-year residentsHospital typeMortality rateSurgeryCABGCall dutiesReporting System dataGraduate Medical EducationOutcomesComparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis
Gaudino M, Hameed I, Di Franco A, Naik A, Demetres M, Biondi-Zoccai G, Bangalore S. Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2021, 165: 1405-1413.e13. PMID: 34176619, PMCID: PMC8805094, DOI: 10.1016/j.jtcvs.2021.05.036.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassCoronary Artery DiseaseHumansIncidencePercutaneous Coronary InterventionRisk FactorsTreatment OutcomeConceptsPercutaneous coronary interventionCoronary artery bypassIncidence rate ratiosCoronary interventionArtery bypassCerebrovascular eventsSYNTAX scoreMultivessel diseaseCause mortalityStatistical heterogeneityRate ratioSystematic reviewCardiac Surgery (SYNTAX) scoreSYNTAX score tertilesCochrane Library databasesMain analysisSignificant statistical heterogeneityRandom-effects modelRevascularization TrialScore tertilesSecondary outcomesSurgery scoreRisk stratificationLibrary databasesNonsignificant increaseAngiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials
Gaudino M, Hameed I, Robinson NB, Ruan Y, Rahouma M, Naik A, Weidenmann V, Demetres M, Tam D, Hare DL, Girardi LN, Biondi‐Zoccai G, Fremes S. Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials. Journal Of The American Heart Association 2021, 10: e019206. PMID: 33686866, PMCID: PMC8174193, DOI: 10.1161/jaha.120.019206.Peer-Reviewed Original ResearchConceptsCoronary artery bypass conduitsTouch saphenous veinAngiographic patency ratesRadial arterySaphenous veinPatency ratesGraft occlusionRandomized trialsBypass conduitRight internal thoracic arteryTouch saphenous vein graftsCoronary bypass surgerySaphenous vein graftsGraft occlusion rateInternal thoracic arteryBest conduitNetwork Meta-AnalysisSystematic literature searchGastroepiploic arteryBypass surgeryPrimary outcomeThoracic arteryAngiographic patencyVein graftsOcclusion rate
2020
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery
Gaudino M, Hameed I, Farkouh ME, Rahouma M, Naik A, Robinson NB, Ruan Y, Demetres M, Biondi-Zoccai G, Angiolillo DJ, Bagiella E, Charlson ME, Benedetto U, Ruel M, Taggart DP, Girardi LN, Bhatt DL, Fremes SE. Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery. JAMA Internal Medicine 2020, 180: 1638-1646. PMID: 33044497, PMCID: PMC7551235, DOI: 10.1001/jamainternmed.2020.4748.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionRandomized clinical trialsCause-specific mortalityCoronary artery diseaseBare metal stentsNoncardiac mortalityCause mortalityCoronary interventionArtery diseaseClinical trialsTrials of PCIEnd pointLeft main diseaseCoronary artery bypassStudy end pointCoronary bypass surgeryData extractionTreatment of patientsCochrane Library databasesPreferred Reporting ItemsRandom-effects modelArtery bypassCardiac mortalityRevascularization TrialBypass surgeryLong-Term Results of the RAPCO Trials
Buxton B, Hayward P, Raman J, Moten S, Rosalion A, Gordon I, Seevanayagam S, Matalanis G, Benedetto U, Gaudino M, Hare D, Gaer J, Negri J, Komeda M, Bellomo R, Doolan L, McNicol L, Brennan J, Chan R, Clark D, Dick R, Dortimer A, Ecclestone D, Farouque O, Fernando D, Horrigan M, Jackson A, Oliver L, Mehta N, Nadurata V, Nadarajah N, Proimos G, Rowe M, Sia B, Webb C, Anaveker N, Barlis P, Calafiore P, Chan B, Cotroneo J, Johns J, Jones E, Kertes P, O’Donnell D, Sylviris S, Tonkin A, Fabini R, Kearney L, Lim R, Molan M, Smith G, Wellman C, Eng J, Hameed I, Shaw M, Gerbo S. Long-Term Results of the RAPCO Trials. Circulation 2020, 142: 1330-1338. PMID: 33017209, DOI: 10.1161/circulationaha.119.045427.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCoronary Artery BypassDisease-Free SurvivalFemaleHumansMaleMammary ArteriesMiddle AgedMortalityRadial ArterySurvival RateVascular PatencyConceptsRight internal thoracic arteryFree right internal thoracic arteryRadial arteryPatient survival estimatesSaphenous veinYears of ageInternal thoracic artery graftsSurvival estimatesFree RITA graftThoracic artery graftsCoprimary end pointsCoronary bypass surgeryInternal thoracic arteryLong-term mortalityLong-term patencyCoronary targetsRA armRITA graftArtery graftBypass surgeryGraft failureRA groupPrimary outcomeThoracic arterySV graftsSurgeons’ Coronary Bypass Practice Patterns in the United States
Gaudino M, Rahouma M, Habib RH, Hameed I, Robinson NB, Farrington WJ, Fremes S, Schwann TA, Girardi LN. Surgeons’ Coronary Bypass Practice Patterns in the United States. Journal Of The American College Of Cardiology 2020, 76: 1714-1715. PMID: 33004137, DOI: 10.1016/j.jacc.2020.07.064.Peer-Reviewed Original ResearchSex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol
Gaudino M, Alexander JH, Egorova N, Kurlansky P, Lamy A, Bakaeen F, Hameed I, Di Franco A, Demetres M, Robinson NB, Chikwe J, Lawton JS, Devereaux PJ, Taggart DP, Flather M, Reents W, Boening A, Diegeler A, Girardi LN, Fremes SE, Benedetto U. Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal Of Cardiac Surgery 2020, 35: 2754-2758. PMID: 32720394, DOI: 10.1111/jocs.14903.Peer-Reviewed Original ResearchConceptsSex-related differencesPooled analysisSystematic reviewPatient-level pooled analysisCoronary artery bypass surgeryMultiple arterial graftsArtery bypass surgeryCoronary artery bypassLong-term followSex-related outcomesTreatment effectsPreferred Reporting ItemsSystematic literature searchPeer-reviewed scientific journalsImpact of sexDifferential treatment effectsCABG studiesArtery bypassCause mortalityPrimary endpointBypass surgeryArterial graftsMyocardial infarctionStudy protocolProspective RegisterAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational studyDiagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review
Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M. Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review. International Journal Of Surgery 2020, 79: 76-83. PMID: 32442689, PMCID: PMC7853700, DOI: 10.1016/j.ijsu.2020.05.036.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassEchocardiographyElectrocardiographyHumansMyocardial InfarctionPostoperative ComplicationsConceptsPerioperative myocardial infarctionCoronary artery bypassArtery bypassMyocardial infarctionPost-operative echocardiographyProcedure-related changesPerioperative morbidityPost-procedure changesCardiac proceduresSignificant complicationsDiagnostic dilemmaPatient outcomesCardiac biomarkersCABGClinical settingDiagnostic testsPerfect diagnostic testInfarctionBypassUnited StatesModalitiesSpecific modalitiesOutcomesMorbidityEchocardiographyEffect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement
Robinson NB, Hameed I, Naik A, Ishtiaq MF, Rahouma M, Girardi LN, Gaudino M. Effect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement. The Annals Of Thoracic Surgery 2020, 110: 2041-2046. PMID: 32343949, PMCID: PMC7799918, DOI: 10.1016/j.athoracsur.2020.03.070.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAorta replacementOperative mortalityConcomitant CABGRisk of MAEsConcomitant coronary artery bypassCoronary artery bypass graftEnd pointConcomitant coronary revascularizationPreoperative pulmonary dysfunctionPrimary end pointSecondary end pointsCoronary artery bypassPerioperative myocardial infarctionArtery bypass graftOnly independent predictorHigh-volume centersAscending Aorta ReplacementCABG groupArtery bypassCoronary revascularizationPulmonary dysfunctionUnadjusted incidenceAdverse eventsPostoperative outcomesCoronary Bypass With the Free Internal Thoracic Artery to Treat Anomalous Right Coronary Artery
Gaudino M, Robinson NB, Hameed I, Girardi LN. Coronary Bypass With the Free Internal Thoracic Artery to Treat Anomalous Right Coronary Artery. The Annals Of Thoracic Surgery 2020, 109: e371-e373. PMID: 31987826, PMCID: PMC7799917, DOI: 10.1016/j.athoracsur.2019.11.063.Peer-Reviewed Original ResearchConceptsInternal thoracic arteryRight coronary arteryCoronary arteryAnomalous originThoracic arteryFree right internal thoracic arteryAnomalous right coronary arteryFree internal thoracic arteryRight coronary artery bypassRight internal thoracic arteryCoronary artery bypassArtery bypassCoronary bypassSurgical treatmentArteryYoung adultsBypassTreatmentCommentary: The evolution of coronary artery bypass surgery: Toward a better operation
Vallely MP, Hameed I, Gaudino M. Commentary: The evolution of coronary artery bypass surgery: Toward a better operation. Journal Of Thoracic And Cardiovascular Surgery 2020, 162: 1122-1124. PMID: 32059931, DOI: 10.1016/j.jtcvs.2020.01.007.Peer-Reviewed Original ResearchCoronary Artery BypassHumans
2019
An Invited Commentary on “Does saphenous vein graft failure even matter? Commentary on: Mid-term and long-term outcomes of endoscopic versus open vein harvesting for coronary artery bypass: A systematic review and meta-analysis” (Int J Surg 2019;72:167–173)
Naik A, Hameed I, Gaudino M. An Invited Commentary on “Does saphenous vein graft failure even matter? Commentary on: Mid-term and long-term outcomes of endoscopic versus open vein harvesting for coronary artery bypass: A systematic review and meta-analysis” (Int J Surg 2019;72:167–173). International Journal Of Surgery 2019, 74: 25-26. PMID: 31862255, DOI: 10.1016/j.ijsu.2019.12.007.Peer-Reviewed Original ResearchEffect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses
Ruan Y, Robinson NB, Naik A, Silva M, Hameed I, Rahouma M, Oakley C, Di Franco A, Zamvar V, Girardi LN, Gaudino M. Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses. International Journal Of Cardiology 2019, 302: 103-107. PMID: 31837901, DOI: 10.1016/j.ijcard.2019.12.009.Peer-Reviewed Original ResearchConceptsPost-operative atrial fibrillationCoronary artery bypassBiA pacingAtrial pacingArtery bypassSecondary outcomesAtrial fibrillationIncidence of POAFGeneric inverse variance methodRight atrial pacingInverse variance methodLargest risk reductionSystematic literature searchPOAF incidenceOperative mortalityPostoperative bleedingPrimary outcomePacing modalitiesClinical trialsLower incidencePacingLiterature searchIncidenceFibrillationRisk reductionIntraoperative graft flow profiles in coronary artery bypass surgery: A meta‐analysis
Silva M, Rong LQ, Naik A, Rahouma M, Hameed I, Robinson B, Ruan Y, Jiang Y, Abed AW, Girardi LN, Gaudino M. Intraoperative graft flow profiles in coronary artery bypass surgery: A meta‐analysis. Journal Of Cardiac Surgery 2019, 35: 279-285. PMID: 31730721, DOI: 10.1111/jocs.14359.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsCoronary Artery BypassCoronary Artery Bypass, Off-PumpHumansIntraoperative PeriodMammary ArteriesVascular PatencyConceptsMean graft flowPulsatility indexVenous graftsIMA graftsVenous conduitsGraft flowArterial graftsPedicled internal mammary artery graftsInternal mammary artery graftCoronary artery bypass surgeryMammary artery graftsPump CABG proceduresArtery bypass surgerySystematic literature searchIMA conduitsOPCABG surgeryArtery graftPrimary endpointSecondary endpointsBypass surgeryCABG proceduresIntraoperative flowONCABGOPCABGGraftThe RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Girardi LN, Hare DL, Taggart DP, Investigators R. The RADial artery International ALliance (RADIAL) extended follow-up study: rationale and study protocol. European Journal Of Cardio-Thoracic Surgery 2019, 56: 1025-1030. PMID: 31535147, DOI: 10.1093/ejcts/ezz247.Peer-Reviewed Original ResearchConceptsPatency ratesSaphenous veinGood mid-term patency ratesMid-term patency ratesCoronary artery bypass surgeryRadial artery graftArtery bypass surgeryEvent-free survivalSaphenous vein graftsLong-term outcomesImproved patency ratesRA armArtery graftPostoperative yearRepeat revascularizationBypass surgeryCardiac eventsVein graftsClinical correlatesStudy protocolObservational studyRole of RasGraftTrialsSurvivalCommentary on: Endoscopic vein harvesting for coronary artery bypass grafting in the UK: what we believe and what we do. A Commentary on the article “Use of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH survey”, Int J Surg 2019;69:146-151
Hameed I, Naik A, Gaudino M. Commentary on: Endoscopic vein harvesting for coronary artery bypass grafting in the UK: what we believe and what we do. A Commentary on the article “Use of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH survey”, Int J Surg 2019;69:146-151. International Journal Of Surgery 2019, 70: 103. PMID: 31499225, DOI: 10.1016/j.ijsu.2019.08.032.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery BypassEndoscopySurveys and QuestionnairesTissue and Organ HarvestingUnited KingdomQuality metrics in coronary artery bypass grafting
Khan FM, Hameed I, Milojevic M, Wingo M, Krieger K, Girardi LN, Prager RL, Gaudino M. Quality metrics in coronary artery bypass grafting. International Journal Of Surgery 2019, 65: 7-12. PMID: 30885838, DOI: 10.1016/j.ijsu.2019.03.007.Peer-Reviewed Original Research