Featured Publications
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data
Gaudino M, Di Franco A, Alexander JH, Bakaeen F, Egorova N, Kurlansky P, Boening A, Chikwe J, Demetres M, Devereaux PJ, Diegeler A, Dimagli A, Flather M, Hameed I, Lamy A, Lawton JS, Reents W, Robinson NB, Audisio K, Rahouma M, Serruys PW, Hara H, Taggart DP, Girardi LN, Fremes SE, Benedetto U. Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal 2021, 43: 18-28. PMID: 34338767, PMCID: PMC8851663, DOI: 10.1093/eurheartj/ehab504.Peer-Reviewed Original ResearchConceptsCoronary artery bypassIndividual patient dataMyocardial infarctionArtery bypassCause mortalityWorse outcomesMultiple arterial graftingPatient dataOff-pump surgeryOutcomes of womenCABG trialBaseline characteristicsPatients 75Secondary outcomesPrimary outcomeArterial graftingCox regressionPooled analysisSurgical techniqueHigh riskHigh incidenceSimilar mortalitySystematic reviewRisk adjustmentMortality
2020
Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol
Gaudino M, Alexander JH, Egorova N, Kurlansky P, Lamy A, Bakaeen F, Hameed I, Di Franco A, Demetres M, Robinson NB, Chikwe J, Lawton JS, Devereaux PJ, Taggart DP, Flather M, Reents W, Boening A, Diegeler A, Girardi LN, Fremes SE, Benedetto U. Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal Of Cardiac Surgery 2020, 35: 2754-2758. PMID: 32720394, DOI: 10.1111/jocs.14903.Peer-Reviewed Original ResearchConceptsSex-related differencesPooled analysisSystematic reviewPatient-level pooled analysisCoronary artery bypass surgeryMultiple arterial graftsArtery bypass surgeryCoronary artery bypassLong-term followSex-related outcomesTreatment effectsPreferred Reporting ItemsSystematic literature searchPeer-reviewed scientific journalsImpact of sexDifferential treatment effectsCABG studiesArtery bypassCause mortalityPrimary endpointBypass surgeryArterial graftsMyocardial infarctionStudy protocolProspective Register
2019
Characteristics and anatomic distribution of early vs late stroke after cardiac surgery
Ivascu NS, Khan FM, Rahouma M, Hameed I, Abouarab A, Segal AZ, Gaudino MFL, Girardi LN. Characteristics and anatomic distribution of early vs late stroke after cardiac surgery. Journal Of Cardiac Surgery 2019, 34: 684-689. PMID: 31212394, DOI: 10.1111/jocs.14121.Peer-Reviewed Original ResearchConceptsLate strokeOperative mortalityCardiac surgeryEarly strokePerioperative strokeOpen cardiac surgeryTime of presentationOpen heart surgeryImpact of strokeWeill Cornell MedicinePerioperative variablesAdult patientsAnterior circulationEmbolic eventsSecondary outcomesCardiopulmonary bypassLikely etiologyAnatomic distributionHeart surgeryRisk factorsAnatomic locationHigh incidencePatientsSurgeryStroke
2018
Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis
Leonard JR, Henry M, Rahouma M, Khan FM, Wingo M, Hameed I, Di Franco A, Guy TS, Girardi LN, Gaudino M. Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis. International Journal Of Cardiology 2018, 278: 300-306. PMID: 30563771, DOI: 10.1016/j.ijcard.2018.12.025.Peer-Reviewed Original ResearchConceptsPost-operative strokeInvasive mitral valve surgeryPooled event rateMitral valve surgeryCT screeningOperative mortalityValve surgeryMyocardial infarctionCT groupNew-onset renal failureLow operative mortalityPerioperative myocardial infarctionCardio-pulmonary bypassComputed Tomography ScreeningPreoperative CT scanRetrograde arterial perfusionInter-group comparisonAortic embolizationNew dialysisPerioperative strokeRenal failureTomography screeningArterial perfusionDecreased incidenceSurgical approach