Featured Publications
Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data
Gaudino M, Di Franco A, Alexander JH, Bakaeen F, Egorova N, Kurlansky P, Boening A, Chikwe J, Demetres M, Devereaux PJ, Diegeler A, Dimagli A, Flather M, Hameed I, Lamy A, Lawton JS, Reents W, Robinson NB, Audisio K, Rahouma M, Serruys PW, Hara H, Taggart DP, Girardi LN, Fremes SE, Benedetto U. Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data. European Heart Journal 2021, 43: 18-28. PMID: 34338767, PMCID: PMC8851663, DOI: 10.1093/eurheartj/ehab504.Peer-Reviewed Original ResearchConceptsCoronary artery bypassIndividual patient dataMyocardial infarctionArtery bypassCause mortalityWorse outcomesMultiple arterial graftingPatient dataOff-pump surgeryOutcomes of womenCABG trialBaseline characteristicsPatients 75Secondary outcomesPrimary outcomeArterial graftingCox regressionPooled analysisSurgical techniqueHigh riskHigh incidenceSimilar mortalitySystematic reviewRisk adjustmentMortalitySystematic Assessment of Online Health Information for Coronary Revascularization
Hameed I, Hameed NUF, Oakley CT, Gambardella I, Bravo C, Angiolillo DJ, Gaudino M. Systematic Assessment of Online Health Information for Coronary Revascularization. JAMA Internal Medicine 2021, 181: 1003-1006. PMID: 33871563, PMCID: PMC8056308, DOI: 10.1001/jamainternmed.2021.1051.Peer-Reviewed Original ResearchConsiderations on the Management of Acute Postoperative Ischemia After Cardiac Surgery: A Scientific Statement From the American Heart Association
Gaudino M, Dangas G, Angiolillo D, Brodt J, Chikwe J, DeAnda A, Hameed I, Rodgers M, Sandner S, Sun L, Yong C, Council O. Considerations on the Management of Acute Postoperative Ischemia After Cardiac Surgery: A Scientific Statement From the American Heart Association. Circulation 2023, 148: 442-454. PMID: 37345559, DOI: 10.1161/cir.0000000000001154.Peer-Reviewed Original ResearchConceptsPostoperative myocardial ischemiaCardiac surgeryMyocardial ischemiaRedo coronary artery bypassCoronary artery bypassLife-threatening complicationsPercutaneous coronary interventionAmerican Heart AssociationLow methodological qualityArtery bypassPostoperative ischemiaCoronary interventionPrompt diagnosisPostoperative careHeart AssociationClinical guidanceSurgical proceduresMethodological qualityCurrent evidenceSurgeryIschemiaMultidisciplinary groupDiagnosisScientific statementConservative strategy
2023
Clinical outcomes of different revascularization approaches for patients with multi-vessel coronary artery disease: A network meta-analysis
Hasan S, Pervez A, Naseeb M, Rajput B, Faheem A, Hameed I, Sá M, Zubair M. Clinical outcomes of different revascularization approaches for patients with multi-vessel coronary artery disease: A network meta-analysis. Perfusion 2023, 39: 1041-1056. PMID: 37294619, DOI: 10.1177/02676591231182585.Peer-Reviewed Original ResearchMulti-vessel coronary artery diseaseCoronary artery diseasePercutaneous coronary interventionPostoperative complicationsArtery diseaseBypass graftSurgical techniquePump coronary artery bypass graftNew-onset atrial fibrillationStent percutaneous coronary interventionCoronary artery bypass surgeryCoronary artery bypass graftInvasive coronary artery bypassNew-onset dialysisHybrid coronary revascularizationArtery bypass graftArtery bypass surgeryCochrane Central RegisterCoronary artery bypassPostoperative myocardial infarctionRandom-effects networkCoronary bypass graftsMost postoperative complicationsArtery bypassCerebrovascular events
2021
The impact of trainees' working hour regulations on outcome in CABG and valve surgery in the State of New York
Amabile A, Mori M, Brooks C, Weininger G, Shang M, Fereydooni S, Komlo CM, Mullan CW, Hameed I, Geirsson A. The impact of trainees' working hour regulations on outcome in CABG and valve surgery in the State of New York. Journal Of Cardiac Surgery 2021, 36: 4582-4590. PMID: 34617327, DOI: 10.1111/jocs.16058.Peer-Reviewed Original ResearchConceptsShort-term outcomesRisk-adjusted mortality ratesDuty hour regulationsTeaching hospitalBetter short-term outcomesWorse short-term outcomesCoronary artery bypassDuty hour policiesOverall surgical volumeArtery bypassCABG surgeryValve surgeryCABG proceduresCardiac surgeryValve proceduresSurgical volumeFirst-year residentsHospital typeMortality rateSurgeryCABGCall dutiesReporting System dataGraduate Medical EducationOutcomesComparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis
Gaudino M, Hameed I, Di Franco A, Naik A, Demetres M, Biondi-Zoccai G, Bangalore S. Comparison of SYNTAX score strata effects of percutaneous and surgical revascularization trials: A meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2021, 165: 1405-1413.e13. PMID: 34176619, PMCID: PMC8805094, DOI: 10.1016/j.jtcvs.2021.05.036.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary artery bypassIncidence rate ratiosCoronary interventionArtery bypassCerebrovascular eventsSYNTAX scoreMultivessel diseaseCause mortalityStatistical heterogeneityRate ratioSystematic reviewCardiac Surgery (SYNTAX) scoreSYNTAX score tertilesCochrane Library databasesMain analysisSignificant statistical heterogeneityRandom-effects modelRevascularization TrialScore tertilesSecondary outcomesSurgery scoreRisk stratificationLibrary databasesNonsignificant increaseDifferences in Long-term Outcomes After Coronary Artery Bypass Grafting Using Single vs Multiple Arterial Grafts and the Association With Sex
Gaudino M, Samadashvili Z, Hameed I, Chikwe J, Girardi LN, Hannan EL. Differences in Long-term Outcomes After Coronary Artery Bypass Grafting Using Single vs Multiple Arterial Grafts and the Association With Sex. JAMA Cardiology 2021, 6: 401-409. PMID: 33355595, PMCID: PMC7758835, DOI: 10.1001/jamacardio.2020.6585.Peer-Reviewed Original ResearchMultiple arterial graftsMultiple arterial graftingMajor adverse cardiac eventsAdverse cardiac eventsCoronary artery bypassArterial graftingAcute myocardial infarctionArterial graftsVital statistics filesArtery bypassCardiac eventsRisk cutoffPropensity-matched patientsSingle arterial graftSingle arterial graftingStatewide cohort studyWorse baseline characteristicsLong-term mortalityPreoperative risk profileRisk of deathLong-term outcomesNew York's Cardiac Surgery Reporting SystemSex-related differencesCerebrovascular eventsBaseline characteristics
2020
Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery
Gaudino M, Hameed I, Farkouh ME, Rahouma M, Naik A, Robinson NB, Ruan Y, Demetres M, Biondi-Zoccai G, Angiolillo DJ, Bagiella E, Charlson ME, Benedetto U, Ruel M, Taggart DP, Girardi LN, Bhatt DL, Fremes SE. Overall and Cause-Specific Mortality in Randomized Clinical Trials Comparing Percutaneous Interventions With Coronary Bypass Surgery. JAMA Internal Medicine 2020, 180: 1638-1646. PMID: 33044497, PMCID: PMC7551235, DOI: 10.1001/jamainternmed.2020.4748.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionRandomized clinical trialsCause-specific mortalityCoronary artery diseaseBare metal stentsNoncardiac mortalityCause mortalityCoronary interventionArtery diseaseClinical trialsTrials of PCIEnd pointLeft main diseaseCoronary artery bypassStudy end pointCoronary bypass surgeryData extractionTreatment of patientsCochrane Library databasesPreferred Reporting ItemsRandom-effects modelArtery bypassCardiac mortalityRevascularization TrialBypass surgeryTreatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis
Gaudino M, Hameed I, Khan FM, Tam DY, Rahouma M, Yongle R, Naik A, Di Franco A, Demetres M, Petrie MC, Jolicoeur EM, Girardi LN, Fremes SE. Treatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis. European Journal Of Cardio-Thoracic Surgery 2020, 59: 293-301. PMID: 33085752, DOI: 10.1093/ejcts/ezaa319.Peer-Reviewed Original ResearchPercutaneous coronary interventionIschemic left ventricular systolic dysfunctionMedical therapyCardiac deathMyocardial infarctionRevascularization strategyHigh mortalityLeft ventricular systolic dysfunctionIschemic left ventricular dysfunctionLeft ventricular ejection fractionBest revascularization strategyLower cardiac deathOptimal revascularization strategyCoronary artery bypassVentricular systolic dysfunctionLeft ventricular dysfunctionVentricular ejection fractionDrug-eluting stentsRelative treatment effectsArtery bypassSystolic dysfunctionVentricular dysfunctionCoronary interventionSecondary outcomesEjection fractionSex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol
Gaudino M, Alexander JH, Egorova N, Kurlansky P, Lamy A, Bakaeen F, Hameed I, Di Franco A, Demetres M, Robinson NB, Chikwe J, Lawton JS, Devereaux PJ, Taggart DP, Flather M, Reents W, Boening A, Diegeler A, Girardi LN, Fremes SE, Benedetto U. Sex‐related differences in outcomes after coronary artery bypass surgery—A patient‐level pooled analysis of randomized controlled trials: rationale and study protocol. Journal Of Cardiac Surgery 2020, 35: 2754-2758. PMID: 32720394, DOI: 10.1111/jocs.14903.Peer-Reviewed Original ResearchConceptsSex-related differencesPooled analysisSystematic reviewPatient-level pooled analysisCoronary artery bypass surgeryMultiple arterial graftsArtery bypass surgeryCoronary artery bypassLong-term followSex-related outcomesTreatment effectsPreferred Reporting ItemsSystematic literature searchPeer-reviewed scientific journalsImpact of sexDifferential treatment effectsCABG studiesArtery bypassCause mortalityPrimary endpointBypass surgeryArterial graftsMyocardial infarctionStudy protocolProspective RegisterAssociation of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting
Gaudino M, Benedetto U, Fremes S, Ballman K, Biondi-Zoccai G, Sedrakyan A, Nasso G, Raman J, Buxton B, Hayward PA, Moat N, Collins P, Webb C, Peric M, Petrovic I, Yoo KJ, Hameed I, Di Franco A, Moscarelli M, Speziale G, Puskas JD, Girardi LN, Hare DL, Taggart DP. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting. JAMA 2020, 324: 179-187. PMID: 32662861, PMCID: PMC7361649, DOI: 10.1001/jama.2020.8228.Peer-Reviewed Original ResearchConceptsCoronary artery bypassSaphenous vein graftsComposite of deathRadial artery graftArtery bypassVein graftsRadial arteryMyocardial infarctionArtery graftCardiovascular outcomesClinical outcomesSaphenous veinLong-term cardiovascular outcomesPatient-level pooled analysisCoronary Artery Bypass GraftingArtery Bypass GraftingIndividual participant dataBypass GraftingAdult patientsComposite outcomeSecondary outcomesPrimary outcomeRandomized trialsPooled analysisObservational studyDiagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review
Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M. Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review. International Journal Of Surgery 2020, 79: 76-83. PMID: 32442689, PMCID: PMC7853700, DOI: 10.1016/j.ijsu.2020.05.036.Peer-Reviewed Original ResearchConceptsPerioperative myocardial infarctionCoronary artery bypassArtery bypassMyocardial infarctionPost-operative echocardiographyProcedure-related changesPerioperative morbidityPost-procedure changesCardiac proceduresSignificant complicationsDiagnostic dilemmaPatient outcomesCardiac biomarkersCABGClinical settingDiagnostic testsPerfect diagnostic testInfarctionBypassUnited StatesModalitiesSpecific modalitiesOutcomesMorbidityEchocardiographyEffect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement
Robinson NB, Hameed I, Naik A, Ishtiaq MF, Rahouma M, Girardi LN, Gaudino M. Effect of Concomitant Coronary Artery Bypass Grafting on Outcomes of Ascending Aorta Replacement. The Annals Of Thoracic Surgery 2020, 110: 2041-2046. PMID: 32343949, PMCID: PMC7799918, DOI: 10.1016/j.athoracsur.2020.03.070.Peer-Reviewed Original ResearchConceptsMajor adverse eventsAorta replacementOperative mortalityConcomitant CABGRisk of MAEsConcomitant coronary artery bypassCoronary artery bypass graftEnd pointConcomitant coronary revascularizationPreoperative pulmonary dysfunctionPrimary end pointSecondary end pointsCoronary artery bypassPerioperative myocardial infarctionArtery bypass graftOnly independent predictorHigh-volume centersAscending Aorta ReplacementCABG groupArtery bypassCoronary revascularizationPulmonary dysfunctionUnadjusted incidenceAdverse eventsPostoperative outcomesCoronary Bypass With the Free Internal Thoracic Artery to Treat Anomalous Right Coronary Artery
Gaudino M, Robinson NB, Hameed I, Girardi LN. Coronary Bypass With the Free Internal Thoracic Artery to Treat Anomalous Right Coronary Artery. The Annals Of Thoracic Surgery 2020, 109: e371-e373. PMID: 31987826, PMCID: PMC7799917, DOI: 10.1016/j.athoracsur.2019.11.063.Peer-Reviewed Original ResearchConceptsInternal thoracic arteryRight coronary arteryCoronary arteryAnomalous originThoracic arteryFree right internal thoracic arteryAnomalous right coronary arteryFree internal thoracic arteryRight coronary artery bypassRight internal thoracic arteryCoronary artery bypassArtery bypassCoronary bypassSurgical treatmentArteryYoung adultsBypassTreatment
2019
An Invited Commentary on “Does saphenous vein graft failure even matter? Commentary on: Mid-term and long-term outcomes of endoscopic versus open vein harvesting for coronary artery bypass: A systematic review and meta-analysis” (Int J Surg 2019;72:167–173)
Naik A, Hameed I, Gaudino M. An Invited Commentary on “Does saphenous vein graft failure even matter? Commentary on: Mid-term and long-term outcomes of endoscopic versus open vein harvesting for coronary artery bypass: A systematic review and meta-analysis” (Int J Surg 2019;72:167–173). International Journal Of Surgery 2019, 74: 25-26. PMID: 31862255, DOI: 10.1016/j.ijsu.2019.12.007.Peer-Reviewed Original ResearchEffect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses
Ruan Y, Robinson NB, Naik A, Silva M, Hameed I, Rahouma M, Oakley C, Di Franco A, Zamvar V, Girardi LN, Gaudino M. Effect of atrial pacing on post-operative atrial fibrillation following coronary artery bypass grafting: Pairwise and network meta-analyses. International Journal Of Cardiology 2019, 302: 103-107. PMID: 31837901, DOI: 10.1016/j.ijcard.2019.12.009.Peer-Reviewed Original ResearchConceptsPost-operative atrial fibrillationCoronary artery bypassBiA pacingAtrial pacingArtery bypassSecondary outcomesAtrial fibrillationIncidence of POAFGeneric inverse variance methodRight atrial pacingInverse variance methodLargest risk reductionSystematic literature searchPOAF incidenceOperative mortalityPostoperative bleedingPrimary outcomePacing modalitiesClinical trialsLower incidencePacingLiterature searchIncidenceFibrillationRisk reductionCommentary on: Endoscopic vein harvesting for coronary artery bypass grafting in the UK: what we believe and what we do. A Commentary on the article “Use of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH survey”, Int J Surg 2019;69:146-151
Hameed I, Naik A, Gaudino M. Commentary on: Endoscopic vein harvesting for coronary artery bypass grafting in the UK: what we believe and what we do. A Commentary on the article “Use of endoscopic vein harvesting (EVH) during coronary artery bypass grafting in United Kingdom: The EVH survey”, Int J Surg 2019;69:146-151. International Journal Of Surgery 2019, 70: 103. PMID: 31499225, DOI: 10.1016/j.ijsu.2019.08.032.Peer-Reviewed Original ResearchQuality metrics in coronary artery bypass grafting
Khan FM, Hameed I, Milojevic M, Wingo M, Krieger K, Girardi LN, Prager RL, Gaudino M. Quality metrics in coronary artery bypass grafting. International Journal Of Surgery 2019, 65: 7-12. PMID: 30885838, DOI: 10.1016/j.ijsu.2019.03.007.Peer-Reviewed Original Research
2018
Endoscopic radial artery harvesting for coronary artery bypass grafting
Naik A, Rahouma M, Spadaccio C, Mehta K, Baudo M, Kamel M, Khan F, Hameed I, Wingo M, Ruan Y, Abouarab A, Hossny M, Girardi L, Gaudino M. Endoscopic radial artery harvesting for coronary artery bypass grafting. Vessel Plus 2018, 2: 38. DOI: 10.20517/2574-1209.2018.62.Peer-Reviewed Original Research