2015
DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine
Shin MS, You S, Kang Y, Lee N, Yoo SA, Park K, Kang KS, Kim SH, Mohanty S, Shaw AC, Montgomery RR, Hwang D, Kang I. DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. The Journal Of Immunology 2015, 195: 2861-2869. PMID: 26276874, PMCID: PMC4561204, DOI: 10.4049/jimmunol.1500877.Peer-Reviewed Original ResearchConceptsDNA methylationDifferential expressionGene expressionCellular traitsEpigenetic mechanismsGene promoterGenome-wide DNA methylationDistinct traitsDNA methylation statusIndividual gene expressionMigratory capacityAutocrine amplification loopImportant biological outcomesPotential biological implicationsMammalian cellsMethylationMethylation statusAmplification loopBiological outcomesTraitsBiological implicationsPromoterEffector memoryExpressionT cells
2013
Defining cellular characteristics of human IL-7Rαlow memory CD8+ T cells using a genome-wide DNA methylation analysis (P1432)
Yoo S, You S, Shin M, Lee N, Kang K, Hwang D, Kang I. Defining cellular characteristics of human IL-7Rαlow memory CD8+ T cells using a genome-wide DNA methylation analysis (P1432). The Journal Of Immunology 2013, 190: 117.16-117.16. DOI: 10.4049/jimmunol.190.supp.117.16.Peer-Reviewed Original ResearchDNA methylationGenome-wide DNA methylation analysisHeritable epigenetic informationPredominant epigenetic mechanismsAbstract DNA methylationDNA methylation analysisEpigenetic informationEpigenetic mechanismsGene promoterMethylation profilingGene expressionTCR triggeringMethylationMethylation analysisGenesHuman agingMemory CD8Cellular characteristicsT cellsCell subsetsIL-7Rα expressionImportant mechanismCellsPotential roleIL-7Rα