Dual roles of IL‐15 in maintaining IL‐7 receptor alpha low CCR7− memory CD8+ T cells in humans via recovering the PI3K/AKT pathway
Kang I, Kim H, Hwang K. Dual roles of IL‐15 in maintaining IL‐7 receptor alpha low CCR7− memory CD8+ T cells in humans via recovering the PI3K/AKT pathway. The FASEB Journal 2008, 22: 846.18-846.18. DOI: 10.1096/fasebj.22.1_supplement.846.18.Peer-Reviewed Original ResearchPI3K/Akt pathwayMemory CD8Lower CCR7IL-15T cellsAkt pathwayIL-7 receptor alphaMemory T cell survivalIL-7 receptor alpha chainHuman peripheral bloodT cell survivalReceptor alpha chainHigher CCR7Peripheral CD8T cell receptor triggeringPeripheral bloodReceptor beta chainT-betCD8IL-7CCR7Effector functionsReceptor alphaEnhanced gene expressionProliferative function