2023
Incidence of cytomegalovirus DNAemia in pediatric kidney, liver, and heart transplant recipients: Efficacy and risk factors associated with failure of weight‐based dosed valganciclovir prophylaxis
Liverman R, Serluco A, Nance G, George R, Rodriguez D, Deshpande S, Mao C, Garro R, Yildirim I. Incidence of cytomegalovirus DNAemia in pediatric kidney, liver, and heart transplant recipients: Efficacy and risk factors associated with failure of weight‐based dosed valganciclovir prophylaxis. Pediatric Transplantation 2023, 27: e14493. PMID: 36945819, DOI: 10.1111/petr.14493.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsPediatric solid organ transplant recipientsCytomegalovirus DNAemiaValganciclovir prophylaxisDose reductionRisk factorsTransplant recipientsImpact of dose adjustmentsRisk factors associated with failureFactors associated with failureOrgan transplant recipientsHeart transplant recipientsIndependent risk factorRetrospective cohort studyAssociated with morbidityCMV DNAemiaCytomegalovirus eventsValganciclovir dosingImmunosuppressive therapyDose adjustmentYounger age groupsDNAemiaValganciclovirRisk stratificationAdverse events
2022
Vaccination in pediatric solid organ transplant: A primer for the immunizing clinician
Chen JK, Cheng J, Liverman R, Serluco A, Corbo H, Yildirim I. Vaccination in pediatric solid organ transplant: A primer for the immunizing clinician. Clinical Transplantation 2022, 36: e14577. PMID: 34997642, DOI: 10.1111/ctr.14577.Peer-Reviewed Original ResearchConceptsVaccine-preventable illnessesPediatric solid organ transplant recipientsSolid organ transplant recipientsPediatric solid organ transplantCorrect immunization schedulesPrevention's Advisory CommitteeOrgan transplant recipientsSolid organ transplantsInfectious Diseases SocietyTime of transplantTransplant recipientsDiseases SocietyVaccine recommendationsIncomplete immunizationImmunization scheduleAntibody titersInadequate responseOrgan transplantsElevated riskPreventable illnessMultiple guidelinesVaccine managementRapid catchDisease controlAmerican Society
2021
#18: Brincidofovir for the Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid-organ Transplant Recipients
Londeree J, Garro R, Romero R, George R, Winterberg P, Liverman R, Serluco A, Shin S, Yildirim I. #18: Brincidofovir for the Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid-organ Transplant Recipients. Journal Of The Pediatric Infectious Diseases Society 2021, 10: s3-s3. DOI: 10.1093/jpids/piaa170.008.Peer-Reviewed Original ResearchPediatric SOT patientsAcute kidney injuryHAdV infectionSolid organ transplantationSOT patientsSevere diseaseResolution of AKIPediatric solid organ transplant recipientsSolid organ transplant recipientsAntiviral treatment optionsInvestigational antiviral drugsPediatric transplant centersBaseline clinical characteristicsDays of therapyMainstay of treatmentResolution of symptomsSubset of patientsHuman adenovirus infectionHAdV viral loadsAdenovirus viremiaBaseline creatinineGraft involvementGraft lossHAdV viremiaReduced immunosuppression
2020
Brincidofovir for the treatment of human adenovirus infection in pediatric solid organ transplant recipients: A case series
Londeree J, Winterberg PD, Garro R, George RP, Shin S, Liverman R, Serluco A, Romero R, Yildirim I. Brincidofovir for the treatment of human adenovirus infection in pediatric solid organ transplant recipients: A case series. Pediatric Transplantation 2020, 24: e13769. PMID: 32558134, DOI: 10.1111/petr.13769.Peer-Reviewed Original ResearchConceptsPediatric SOT recipientsSOT recipientsCase seriesSevere diseasePediatric solid organ transplant recipientsSolid organ transplant recipientsType of allograftMainstay of treatmentOrgan transplant recipientsSeverity of diseaseHuman adenovirus infectionHAdV diseaseHAdV viremiaPediatric recipientsTransplant recipientsHAdV infectionDisease courseAntiviral therapySignificant morbidityDisease presentationUS FDAAdenovirus infectionBrincidofovirDiseaseRecipients
2018
Impact of Pharmacy-Initiated Interventions on Influenza Vaccination Rates in Pediatric Solid Organ Transplant Recipients
Gattis S, Yildirim I, Shane AL, Serluco S, McCracken C, Liverman R. Impact of Pharmacy-Initiated Interventions on Influenza Vaccination Rates in Pediatric Solid Organ Transplant Recipients. Journal Of The Pediatric Infectious Diseases Society 2018, 8: 525-530. PMID: 30307524, DOI: 10.1093/jpids/piy095.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsPediatric SOT recipientsInfluenza vaccination ratesOrgan transplant recipientsSOT recipientsTransplant recipientsInfluenza infectionVaccination ratesVaccination coveragePediatric solid organ transplant recipientsSubsequent graft dysfunctionHeart transplant recipientsInfluenza vaccination coveragePre-post study designNumber of patientsRate of vaccinationGraft dysfunctionInfluenza immunizationInfluenza vaccinationChart reviewPharmacy interventionsMedian timeVaccine coverageTransplant servicesInfluenza rates