2023
Incidence of cytomegalovirus DNAemia in pediatric kidney, liver, and heart transplant recipients: Efficacy and risk factors associated with failure of weight‐based dosed valganciclovir prophylaxis
Liverman R, Serluco A, Nance G, George R, Rodriguez D, Deshpande S, Mao C, Garro R, Yildirim I. Incidence of cytomegalovirus DNAemia in pediatric kidney, liver, and heart transplant recipients: Efficacy and risk factors associated with failure of weight‐based dosed valganciclovir prophylaxis. Pediatric Transplantation 2023, 27: e14493. PMID: 36945819, DOI: 10.1111/petr.14493.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsPediatric solid organ transplant recipientsCytomegalovirus DNAemiaValganciclovir prophylaxisDose reductionRisk factorsTransplant recipientsImpact of dose adjustmentsRisk factors associated with failureFactors associated with failureOrgan transplant recipientsHeart transplant recipientsIndependent risk factorRetrospective cohort studyAssociated with morbidityCMV DNAemiaCytomegalovirus eventsValganciclovir dosingImmunosuppressive therapyDose adjustmentYounger age groupsDNAemiaValganciclovirRisk stratificationAdverse events
2021
#77: Impact of Targeted Tacrolimus Levels on BK Polyomavirus DNAemia Among Pediatric Kidney Transplant Recipients
Yildirim I, Liverman R, Serluco S, George R, Garro R, Winterberg P. #77: Impact of Targeted Tacrolimus Levels on BK Polyomavirus DNAemia Among Pediatric Kidney Transplant Recipients. Journal Of The Pediatric Infectious Diseases Society 2021, 10: s4-s4. DOI: 10.1093/jpids/piaa170.011.Peer-Reviewed Original ResearchPost-intervention cohortKidney transplant recipientsTacrolimus levelsTransplant recipientsKidney transplantPediatric kidney transplant recipientsPre-intervention cohortTacrolimus target levelsQuality improvement studyAllograft dysfunctionBK viremiaGraft lossImmunosuppression reductionUncontrolled viremiaBK nephropathyInfectious complicationsKidney transplantationMedian ageSerious complicationsMedian timeBK polyomavirusIncidence rateDNAemiaTrough targetsProspective monitoring