A Quarter of a Century Later: What is Dofetilide’s Clinical Role Today?
Wolbrette DL, Hussain S, Maraj I, Naccarelli GV. A Quarter of a Century Later: What is Dofetilide’s Clinical Role Today? Journal Of Cardiovascular Pharmacology And Therapeutics 2018, 24: 3-10. PMID: 29940780, DOI: 10.1177/1074248418784288.Peer-Reviewed Original ResearchConceptsAtrial fibrillationAtrial flutterClass III antiarrhythmic agentPost-myocardial infarction patientsAcceptable renal functionAtrioventricular nodal blockadeAcceptable safety profileNormal QT intervalParoxysmal atrial fibrillationReal-world efficacyCreatinine clearanceRenal functionSymptomatic patientsHeart failureAtrial tachycardiaPersistent arrhythmiaSafety profileSinus rhythmAntiarrhythmic agentsInfarction patientsVentricular tachycardiaClinical trialsQT intervalDrug trialsDrug Administration