2022
A comparison of methods to harmonize cortical thickness measurements across scanners and sites
Sun D, Rakesh G, Haswell CC, Logue M, Baird CL, O'Leary EN, Cotton AS, Xie H, Tamburrino M, Chen T, Dennis EL, Jahanshad N, Salminen LE, Thomopoulos SI, Rashid F, Ching CRK, Koch SBJ, Frijling JL, Nawijn L, van Zuiden M, Zhu X, Suarez-Jimenez B, Sierk A, Walter H, Manthey A, Stevens JS, Fani N, van Rooij SJH, Stein M, Bomyea J, Koerte IK, Choi K, van der Werff SJA, Vermeiren RRJM, Herzog J, Lebois LAM, Baker JT, Olson EA, Straube T, Korgaonkar MS, Andrew E, Zhu Y, Li G, Ipser J, Hudson AR, Peverill M, Sambrook K, Gordon E, Baugh L, Forster G, Simons RM, Simons JS, Magnotta V, Maron-Katz A, du Plessis S, Disner SG, Davenport N, Grupe DW, Nitschke JB, deRoon-Cassini TA, Fitzgerald JM, Krystal JH, Levy I, Olff M, Veltman DJ, Wang L, Neria Y, De Bellis MD, Jovanovic T, Daniels JK, Shenton M, van de Wee NJA, Schmahl C, Kaufman ML, Rosso IM, Sponheim SR, Hofmann DB, Bryant RA, Fercho KA, Stein DJ, Mueller SC, Hosseini B, Phan KL, McLaughlin KA, Davidson RJ, Larson CL, May G, Nelson SM, Abdallah CG, Gomaa H, Etkin A, Seedat S, Harpaz-Rotem I, Liberzon I, van Erp TGM, Quidé Y, Wang X, Thompson PM, Morey RA. A comparison of methods to harmonize cortical thickness measurements across scanners and sites. NeuroImage 2022, 261: 119509. PMID: 35917919, PMCID: PMC9648725, DOI: 10.1016/j.neuroimage.2022.119509.Peer-Reviewed Original ResearchRemodeling of the Cortical Structural Connectome in Posttraumatic Stress Disorder: Results From the ENIGMA-PGC Posttraumatic Stress Disorder Consortium
Sun D, Rakesh G, Clarke-Rubright EK, Haswell CC, Logue MW, O'Leary EN, Cotton AS, Xie H, Dennis EL, Jahanshad N, Salminen LE, Thomopoulos SI, Rashid FM, Ching CRK, Koch SBJ, Frijling JL, Nawijn L, van Zuiden M, Zhu X, Suarez-Jimenez B, Sierk A, Walter H, Manthey A, Stevens JS, Fani N, van Rooij SJH, Stein MB, Bomyea J, Koerte I, Choi K, van der Werff SJA, Vermeiren RRJM, Herzog JI, Lebois LAM, Baker JT, Ressler KJ, Olson EA, Straube T, Korgaonkar MS, Andrew E, Zhu Y, Li G, Ipser J, Hudson AR, Peverill M, Sambrook K, Gordon E, Baugh LA, Forster G, Simons RM, Simons JS, Magnotta VA, Maron-Katz A, du Plessis S, Disner SG, Davenport ND, Grupe D, Nitschke JB, deRoon-Cassini TA, Fitzgerald J, Krystal JH, Levy I, Olff M, Veltman DJ, Wang L, Neria Y, De Bellis MD, Jovanovic T, Daniels JK, Shenton ME, van de Wee NJA, Schmahl C, Kaufman ML, Rosso IM, Sponheim SR, Hofmann DB, Bryant RA, Fercho KA, Stein DJ, Mueller SC, Phan KL, McLaughlin KA, Davidson RJ, Larson C, May G, Nelson SM, Abdallah CG, Gomaa H, Etkin A, Seedat S, Harpaz-Rotem I, Liberzon I, Wang X, Thompson PM, Morey RA. Remodeling of the Cortical Structural Connectome in Posttraumatic Stress Disorder: Results From the ENIGMA-PGC Posttraumatic Stress Disorder Consortium. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 935-948. PMID: 35307575, PMCID: PMC9835553, DOI: 10.1016/j.bpsc.2022.02.008.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCortical thicknessStructural covarianceComorbid depressionControl subjectsLarge effect sizesStress disorderEffect sizeTrauma-exposed control subjectsCase-control differencesCortical surface areaInflammatory processClinical dataResting-state functional connectivity networksPositive pairwise correlationsCortical differencesCortical regionsCortical neuroanatomyStress hormonesFunctional connectivity networksPTSD casesSmall effect sizesGroup differencesStructural networkStructural connectome
2021
The hidden burden of social anxiety disorder in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Byrne SP, Fogle BM, Asch R, Esterlis I, Harpaz-Rotem I, Tsai J, Pietrzak RH. The hidden burden of social anxiety disorder in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2021, 291: 9-14. PMID: 34022553, DOI: 10.1016/j.jad.2021.04.088.Peer-Reviewed Original ResearchConceptsU.S. military veteransPsychiatric comorbidityPsychiatric disordersSuicidal ideationU.S. veteransAnxiety disordersComorbid psychiatric disordersMilitary veteransLifetime major depressionImportance of screeningPrevalent mental disordersSocial anxiety disorderMental health functioningCurrent suicidal ideationMeasures of functioningPosttraumatic stress disorderLifetime social anxiety disorderIncremental burdenMultivariable analysisPsychiatric morbidityNational HealthRepresentative sampleMajor depressionFunctional impairmentPsychiatric history
2016
FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study
Watkins LE, Han S, Harpaz-Rotem I, Mota NP, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH. FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology 2016, 69: 98-105. PMID: 27078785, DOI: 10.1016/j.psyneuen.2016.04.001.Peer-Reviewed Original ResearchAdultAllelesChildChild AbuseGene-Environment InteractionGenetic Predisposition to DiseaseGenotypeHumansHypothalamo-Hypophyseal SystemLinkage DisequilibriumMalePituitary-Adrenal SystemPolymorphism, Single NucleotideRisk FactorsStress Disorders, Post-TraumaticSubstance-Related DisordersTacrolimus Binding ProteinsVeterans
2013
POSTTRAUMATIC STRESS DISORDER AMONG PRESCHOOLERS EXPOSED TO ONGOING MISSILE ATTACKS IN THE GAZA WAR
Kaufman‐Shriqui V, Werbeloff N, Faroy M, Meiri G, Shahar DR, Fraser D, Novack Y, Bilenko N, Vardi H, Elhadad N, Pietrzak RH, Harpaz‐Rotem I. POSTTRAUMATIC STRESS DISORDER AMONG PRESCHOOLERS EXPOSED TO ONGOING MISSILE ATTACKS IN THE GAZA WAR. Depression And Anxiety 2013, 30: 425-431. PMID: 23620192, DOI: 10.1002/da.22121.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderOnly significant risk factorOngoing missile attacksChild posttraumatic stress disorderSignificant risk factorsYoung childrenPsychosomatic reactionsRisk factorsMaternal anxietyPosttraumatic stress symptomsSociodemographic characteristicsMothers of preschoolersStress disorderPsychosomatic correlatesMothersChildrenPsychosomatic symptomatologyStress symptomsHigh ratePreschool childrenTraumaDisordersMissile attacksTraumatic experiencesConstipation
2012
The Role of Coping, Resilience, and Social Support in Mediating the Relation Between PTSD and Social Functioning in Veterans Returning from Iraq and Afghanistan
Tsai J, Harpaz-Rotem I, Pietrzak RH, Southwick SM. The Role of Coping, Resilience, and Social Support in Mediating the Relation Between PTSD and Social Functioning in Veterans Returning from Iraq and Afghanistan. Psychiatry 2012, 75: 135-149. PMID: 22642433, DOI: 10.1521/psyc.2012.75.2.135.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAfghan Campaign 2001-AfghanistanChildCross-Sectional StudiesData Interpretation, StatisticalFamily RelationsFemaleHumansInterpersonal RelationsIraqIraq War, 2003-2011MalePersonal SatisfactionResilience, PsychologicalSelf ReportSocial BehaviorSocial SupportStress Disorders, Post-TraumaticUnited StatesVeteransConceptsPosttraumatic stress disorderTreatment-seeking veteransSocial functioningSocial supportSecure relationshipsLife satisfactionRole of copingPoor social functioningSeries of questionnairesLower life satisfactionAcceptance of changeRelationship satisfactionSocial avoidanceExcessive worryRomantic partnersFamily functioningStress disorderPsychotherapeutic interventionsCommon psychiatric disordersLess cohesionFunctioningPartner satisfactionMental health careVA primary careCoping
2007
Clinical Epidemiology of Urban Violence
Harpaz-Rotem I, Murphy RA, Berkowitz S, Marans S, Rosenheck RA. Clinical Epidemiology of Urban Violence. Journal Of Interpersonal Violence 2007, 22: 1479-1490. PMID: 17925294, DOI: 10.1177/0886260507305571.Peer-Reviewed Original ResearchConceptsChild Development-Community Policing ProgramClinical epidemiologyCommunity Policing ProgramLaw enforcement agentsMental health cliniciansRoles of participantsPhysical injuryUrban violenceU.S. citiesClinical correlatesHealth cliniciansHigh riskMajority of incidentsParticipants' homesTypes of incidentsViolenceChildren's exposureMultivariate regressionInjuryEpidemiologyHomeExposureFemalesThreatIncidents
2006
Prescribing practices of psychiatrists and primary care physicians caring for children with mental illness
Harpaz‐Rotem I, Rosenheck RA. Prescribing practices of psychiatrists and primary care physicians caring for children with mental illness. Child Care Health And Development 2006, 32: 225-238. PMID: 16441857, DOI: 10.1111/j.1365-2214.2006.00588.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorAge DistributionAnxiety DisordersAttention Deficit Disorder with HyperactivityChildChild Behavior DisordersDrug Administration ScheduleFamily PracticeFemaleHealth Services AccessibilityHumansInsurance, HealthMaleMental DisordersMood DisordersPractice Patterns, Physicians'PsychiatryPsychotropic DrugsSex DistributionTime FactorsConceptsPrimary care physiciansMental health servicesPsychotropic medicationsMental illnessCare physiciansPrescribing practicesHealth servicesProportion of patientsCollaborative care modelType of medicationEffective mental health servicesCombination of psychotherapyMental health specialistsPsychotropic prescribing practicesSignificant differencesPatient characteristicsHealth insurance plansMarketScan databasePrivate health insurance plansCalendar year 2000Mood disordersCare modelEffective treatmentMedicationsClinical contactThe Mental Health of Children Exposed to Maternal Mental Illness and Homelessness
Harpaz-Rotem I, Rosenheck RA, Desai R. The Mental Health of Children Exposed to Maternal Mental Illness and Homelessness. Community Mental Health Journal 2006, 42: 437-448. PMID: 16404686, DOI: 10.1007/s10597-005-9013-8.Peer-Reviewed Original ResearchConceptsMental health statusChild mental healthMental healthMothers' mental health statusEmotional problemsMaternal mental illnessHistory of incarcerationClinical statusEffects of exposureHealth statusPreventive interventionsMental illnessSignificant associationNumber of reportsChildren's exposureFamily interventionsChildren's emotional problemsTraumaLongitudinal studyChildrenAssociationHealthExposureInterventionPhysical needs
2005
Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000
Harpaz-Rotem I, Leslie DL, Martin A, Rosenheck RA. Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000. Social Psychiatry And Psychiatric Epidemiology 2005, 40: 642-647. PMID: 16133747, DOI: 10.1007/s00127-005-0923-0.Peer-Reviewed Original ResearchConceptsSpecific mental health disordersPrivate health insurance claimsPsychiatric inpatient settingsMental health disordersPsychiatric inpatient servicesSubstance abuse disordersHealth insurance claimsMental health problemsAdmission diagnosisHospitalized childrenNationwide databaseInpatient settingOdds ratioAbuse disordersPsychiatric diagnosisInpatient servicesHealth disordersBipolar disorderHealth problemsPrevalenceSignificant decreaseDisordersChildrenDiagnosisInsurance claimsThe earliest memory in individuals raised in either traditional and reformed kibbutz or outside the kibbutz
Harpaz-Rotem I, Hirst W. The earliest memory in individuals raised in either traditional and reformed kibbutz or outside the kibbutz. Memory 2005, 13: 51-62. PMID: 15724907, DOI: 10.1080/09658210344000567.Peer-Reviewed Original Research
2004
Treatment Retention Among Children Entering a New Episode of Mental Health Care
Harpaz-Rotem I, Leslie D, Rosenheck RA. Treatment Retention Among Children Entering a New Episode of Mental Health Care. Psychiatric Services 2004, 55: 1022-1028. PMID: 15345762, DOI: 10.1176/appi.ps.55.9.1022.Peer-Reviewed Original ResearchConceptsMental health servicesService usePsychiatric hospitalizationHealth servicesRecent psychiatric hospitalizationSeverity of illnessPrimary care physiciansMental health contactsMental health specialistsMental health careMental health professionalsCare physiciansHealth contactsOverall mean numberSix-month periodLower riskNew episodesTreatment retentionType of insuranceHealth specialistsHealth professionalsPrivate insuranceAverage durationTotal numberInsurance coverageChanges in Outpatient Psychiatric Diagnosis in Privately Insured Children and Adolescents from 1995 to 2000
Harpaz-Rotem I, Rosenheck RA. Changes in Outpatient Psychiatric Diagnosis in Privately Insured Children and Adolescents from 1995 to 2000. Child Psychiatry & Human Development 2004, 34: 329-340. PMID: 15039605, DOI: 10.1023/b:chud.0000020683.08514.2d.Peer-Reviewed Original ResearchConceptsOutpatient mental health servicesProportion of childrenMental health servicesSubstance abuse disordersMental health problemsHealth insurance plansPrivate health insurance plansDepressive disorderAbuse disordersPsychiatric diagnosisDiagnostic prevalenceBipolar disorderHealth problemsHealth servicesInsurance plansDiagnostic patternsDisordersChildrenYear periodAdolescentsPrevalenceDiagnosisYears 1995Dramatic increase