2023
Evaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Stiltner B, Fischer I, Duek O, Polimanti R, Harpaz-Rotem I, Pietrzak R. Evaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2023, 346: 303-307. PMID: 37979626, DOI: 10.1016/j.jad.2023.11.041.Peer-Reviewed Original ResearchConceptsIndex traumaPTSD symptomsNational HealthPosttraumatic stress disorder (PTSD) symptomsVeterans StudyMilitary veteransTrauma-exposed populationsClinician-administered interviewU.S. military veteransConfirmatory factor analysisDSM-5 modelStrong significant associationTrauma exposureIntrusive symptomsDisorder symptomsCombat exposureHigh riskU.S. veteransDSM-5Significant associationSymptomsInterpersonal violenceFactor analysisPTSDScarce research
2021
In Their Own Words: Veteran Experiences with Evidence-Based Treatments for PTSD in the Veterans Health Administration
Doran JM, O’Shea M, Harpaz-Rotem I. In Their Own Words: Veteran Experiences with Evidence-Based Treatments for PTSD in the Veterans Health Administration. Psychiatric Quarterly 2021, 92: 961-980. PMID: 33409926, DOI: 10.1007/s11126-020-09861-z.Peer-Reviewed Original ResearchConceptsVeterans Affairs Healthcare SystemEvidence-based psychotherapiesVeterans Health AdministrationEvidence-based treatmentsOutpatient PTSD clinicVeterans' experiencesTreatment completionTreatment outcomesPTSD clinicTreatment protocolHealth AdministrationHealthcare systemTreatmentPTSDOutcomesVeteransVeterans' perceptionsMultiple barriersTreatment dropAssessment toolPresent study
2019
Examining the nonresponse phenomenon: Factors associated with treatment response in a national sample of veterans undergoing residential PTSD treatment
Sripada RK, Blow FC, Rauch SAM, Ganoczy D, Hoff R, Harpaz-Rotem I, Bohnert KM. Examining the nonresponse phenomenon: Factors associated with treatment response in a national sample of veterans undergoing residential PTSD treatment. Journal Of Anxiety Disorders 2019, 63: 18-25. PMID: 30785007, DOI: 10.1016/j.janxdis.2019.02.001.Peer-Reviewed Original ResearchConceptsResidential PTSD treatmentPTSD treatmentPTSD symptom changeTreatment-seeking veteransContextual protective factorsPhysical health resourcesNational sampleLarge national samplePsychological stateIndividual-level factorsLife eventsMultilevel modelingSymptom changeTreatment entryPoor treatment responseProtective factorsWorse treatment responsePersonality disorderPTSDBetter treatment responseTreatment responseCurrent studyGreater pain severityVeteransTheory of resources
2018
In Their Own Words: Clinician Experiences and Challenges in Administering Evidence-Based Treatments for PTSD in the Veterans Health Administration
Doran JM, O’Shea M, Harpaz-Rotem I. In Their Own Words: Clinician Experiences and Challenges in Administering Evidence-Based Treatments for PTSD in the Veterans Health Administration. Psychiatric Quarterly 2018, 90: 11-27. PMID: 30209719, DOI: 10.1007/s11126-018-9604-5.Peer-Reviewed Original ResearchConceptsVeterans Affairs Healthcare SystemEvidence-based psychotherapiesClinician experienceVeteran populationVeterans Health AdministrationOutpatient PTSD clinicClinicians' perceptionsPTSD clinicClinical practiceHealth AdministrationTreatment effectivenessHealthcare systemPTSDTreatmentOne-hour focus groupsCliniciansRepresentative quotesPresent studyFocus groupsActive ingredientsChange/improvementClinicPopulationThe Unique Roles of Emotional Numbing and Arousal Symptoms in Relation to Social Connectedness Among Military Veterans in Residential Treatment for PTSD
Sippel LM, Watkins LE, Pietrzak RH, Hoff R, Harpaz-Rotem I. The Unique Roles of Emotional Numbing and Arousal Symptoms in Relation to Social Connectedness Among Military Veterans in Residential Treatment for PTSD. Psychiatry 2018, 81: 271-282. PMID: 30015602, DOI: 10.1080/00332747.2017.1395313.Peer-Reviewed Original ResearchConceptsPTSD symptom clustersDysphoric arousal symptomsPoor social connectednessArousal symptomsEmotional numbingSocial connectednessResidential treatmentPosttraumatic stress disorder (PTSD) symptomsSymptom clustersEmotional numbing symptomsMilitary veteransAnxious arousal symptomsFive-factor modelU.S. military veteransAnxious arousalDysphoric arousalNumbing symptomsInterpersonal functioningTrauma recoveryDisorder symptomsCase conceptualizationGreater distressMore distressPTSDSupportive people
2017
Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic
Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic. Current Psychiatry Reports 2017, 19: 74. PMID: 28844076, PMCID: PMC5904792, DOI: 10.1007/s11920-017-0829-z.Peer-Reviewed Original ResearchConceptsSynaptic connectivityRapid-acting treatmentPathophysiology of PTSDPotential clinical importanceTreatment of PTSDSynaptic lossPurpose of ReviewStudiesDisconnection syndromeClinical importanceNovel pharmacotherapeuticsNovel therapeuticsPTSD symptomsRecent FindingsHerePTSDPathophysiologyKetamineTreatmentDisordersTherapeutic applicationsStress-related lossesSyndromeSymptomsPharmacotherapeutics
2013
Military Sexual Assault and Homeless Women Veterans: Clinical Correlates and Treatment Preferences
Decker SE, Rosenheck RA, Tsai J, Hoff R, Harpaz-Rotem I. Military Sexual Assault and Homeless Women Veterans: Clinical Correlates and Treatment Preferences. Women's Health Issues 2013, 23: e373-e380. PMID: 24183412, DOI: 10.1016/j.whi.2013.09.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultCrime VictimsFemaleHumansIll-Housed PersonsMental HealthMiddle AgedMilitary PersonnelMultivariate AnalysisPatient Acceptance of Health CarePatient PreferencePrevalenceRetrospective StudiesRisk FactorsSelf ReportSex OffensesSocioeconomic FactorsStress Disorders, Post-TraumaticSurveys and QuestionnairesUnited StatesUnited States Department of Veterans AffairsVeteransConceptsMilitary sexual assaultHomeless female veteransFemale veteransSexual assaultGreater mental health symptomsMental health symptomsSerious psychological sequelaePsychological distressPsychological sequelaeHomeless women veteransHealth symptomsThird of participantsTreatment preferencesPsychiatric symptomsCurrent homelessnessVeteransWomen veteransAssaultGreater severityClinical correlatesPTSDClinical symptomsHomeless womenObservational studyHigh risk
2009
Assessing the Effects of Maternal Symptoms and Homelessness on the Mental Health Problems in their Children
Harpaz‐Rotem I, Rosenheck R, Desai R. Assessing the Effects of Maternal Symptoms and Homelessness on the Mental Health Problems in their Children. Child And Adolescent Mental Health 2009, 14: 168-174. DOI: 10.1111/j.1475-3588.2008.00519.x.Peer-Reviewed Original ResearchChild mental healthMental healthMaternal posttraumatic stress disorder symptomsPosttraumatic stress disorder (PTSD) symptomsMaternal PTSD symptomsMeasures of childMaternal psychiatric symptomsPsychiatric symptomsMental health problemsPTSD symptomsDisorder symptomsTraumatic experiencesAnxiety symptomsLongitudinal associationsSubstance abuseAnalytic strategiesChild wellMaternal symptomsPsychiatric conditionsProgram entryChildrenDepressionPTSDMothersHealth problems