2022
Potential clinical relevance of cardiac magnetic resonance to diagnose cardiac light chain amyloidosis
Dohy Z, Szabo L, Pozsonyi Z, Csecs I, Toth A, Suhai F, Czimbalmos C, Szucs A, Kiss A, Becker D, Merkely B, Vago H. Potential clinical relevance of cardiac magnetic resonance to diagnose cardiac light chain amyloidosis. PLOS ONE 2022, 17: e0269807. PMID: 35696411, PMCID: PMC9191721, DOI: 10.1371/journal.pone.0269807.Peer-Reviewed Original ResearchConceptsCardiac AL amyloidosisCardiac magnetic resonanceLate gadolinium enhancementAL amyloidosisOptimal diagnostic performanceHypertrophic cardiomyopathyDegree of left ventricular (LV) hypertrophyReduced global LV longitudinal strainDiagnostic performanceLeft ventricular (LV) hypertrophyPattern of late gadolinium enhancementGlobal LV longitudinal strainSubendocardial late gadolinium enhancementCardiac magnetic resonance examinationCardiac magnetic resonance parametersCardiac light-chain amyloidosisDifferential diagnosis of cardiomyopathyLV strain parametersCardiac transthyretin amyloidosisLV) hypertrophyLV longitudinal strainDiagnosis of cardiomyopathyLight chain amyloidosisCardiac light chainsPotential clinical relevance
2021
The role of feature-tracking strain analysis in the differentiation of cardiac amyloidosis from hypertrophic cardiomyopathy
Dohy Z, Szabo L, Pozsonyi Z, Csecs I, Toth A, Suhai F, Czimbalmos C, Szucs A, Kiss A, Becker D, Merkely B, Vago H. The role of feature-tracking strain analysis in the differentiation of cardiac amyloidosis from hypertrophic cardiomyopathy. European Heart Journal 2021, 42: ehab724.0240. DOI: 10.1093/eurheartj/ehab724.0240.Peer-Reviewed Original ResearchCardiac involvement of amyloidosisLeft ventricular ejection fractionLate gadolinium enhancementCardiac magnetic resonanceAmount of late gadolinium enhancementHypertrophic cardiomyopathy patientsFeature-tracking strain analysisCA patientsHypertrophic cardiomyopathyBasal LSDiagnostic accuracyPattern of late gadolinium enhancementCardiac magnetic resonance diagnosisCardiac magnetic resonance examinationSignificant independent predictors of mortalityCox proportional hazards regression analysisIndependent predictor of mortalityLV strain parametersRegional strain valuesYears of follow-upProportional hazards regression analysisVentricular ejection fractionOptimal cutoff valueLog-rank testDiagnosis of CAMachine learning phenotyping of scarred myocardium from cine in hypertrophic cardiomyopathy
Mancio J, Pashakhanloo F, El-Rewaidy H, Jang J, Joshi G, Csecs I, Ngo L, Rowin E, Manning W, Maron M, Nezafat R. Machine learning phenotyping of scarred myocardium from cine in hypertrophic cardiomyopathy. European Heart Journal - Cardiovascular Imaging 2021, 23: 532-542. PMID: 33779725, PMCID: PMC9125682, DOI: 10.1093/ehjci/jeab056.Peer-Reviewed Original Research
2020
Differentiation between physiological sport adaptation and hypertrophic cardiomyopathy in highly trained athletes using cardiac magnetic resonance
Czimbalmos C, Nardocci C, Deetjen E, Szabo L, Dohy Z, Toth A, Suhai F, Csecs I, Horvath V, Kiss O, Sydo N, Merkely B, Vago H. Differentiation between physiological sport adaptation and hypertrophic cardiomyopathy in highly trained athletes using cardiac magnetic resonance. European Heart Journal 2020, 41: ehaa946.3119. DOI: 10.1093/ehjci/ehaa946.3119.Peer-Reviewed Original ResearchCardiac magnetic resonance parametersCardiac magnetic resonanceLate gadolinium enhancementDiagnosis of hypertrophic cardiomyopathyHypertrophic cardiomyopathyCut-off valueHCM patientsHealthy athletesPresence of late gadolinium enhancementOptimal cut-off valueCardiac magnetic resonance characteristicsConventional CMR parametersReceiver operating curve analysisDiagnose HCMEnd-diastolic wall thicknessPathological left ventricular hypertrophyOperating curve analysisGlobal longitudinalGadolinium enhancementLV functionVentricular hypertrophyCMR parametersClinical conundrumHypertrophy patternCurve analysisAssociation Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy
Csecs I, Pashakhanloo F, Paskavitz A, Jang J, Al‐Otaibi T, Neisius U, Manning W, Nezafat R. Association Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016797. PMID: 33006296, PMCID: PMC7792406, DOI: 10.1161/jaha.120.016797.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementSeptal late gadolinium enhancementLV ejection fractionNonischemic cardiomyopathyExtent of fibrosisCardiovascular magnetic resonanceEjection fractionImpaired global circumferential strainImpaired LV ejection fractionLate gadolinium enhancement groupsDepressed LV ejection fractionClinical cardiovascular magnetic resonanceLeft ventricular (LVLGE-negative groupCircumferential strainGlobal radial strainGlobal longitudinal strainRadial strainGlobal circumferential strainLV deformation parametersGlobal LV functionAdverse cardiovascular outcomesLGE-positiveNonischemic fibrosisFibrosis burdenP363 Cardiac magnetic resonance characteristics of patients in the grey zone of hypertrophy
Czimbalmos C, Csecs I, Horvath V, Deetjen E, Nardocci C, Dohy Z, Szabo L, Suhai F, Toth A, Sydo N, Kiss O, Merkely B, Vago H. P363 Cardiac magnetic resonance characteristics of patients in the grey zone of hypertrophy. European Heart Journal - Cardiovascular Imaging 2020, 21 DOI: 10.1093/ehjci/jez319.212.Peer-Reviewed Original ResearchLate gadolinium enhancementCardiac magnetic resonancePresence of late gadolinium enhancementHCM patientsHypertrophic cardiomyopathyInter-observer analysisHealthy athletesGadolinium enhancementCardiac magnetic resonance characteristicsStandard deviation of timeConventional CMR parametersMale HCM patientsEnd-diastolic wall thicknessGlobal strain valuesCut-off valueCharacteristics of patientsGray zoneGlobal longitudinalIntraventricular dyssynchronyHypertrophic segmentsCMR parametersDifferential diagnosisDelayed contrastHCM groupPatient group
2019
Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study
Csécs I, Yamaguchi T, Kheirkhahan M, Czimbalmos C, Fochler F, Kholmovski E, Morris A, Kaur G, Vago H, Merkely B, Chelu M, Marrouche N, Wilson B. Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study. International Journal Of Cardiology 2019, 305: 154-160. PMID: 31874788, DOI: 10.1016/j.ijcard.2019.12.010.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonance imagingCardiac magnetic resonance studyLA-LGEPredictors of recurrenceLate gadolinium enhancementLA volumeAtrial fibrillationPredictor of arrhythmia recurrenceSuccess of AF ablationAssessment of LA functionSelection of optimal treatment strategiesSuccess of atrial fibrillationOptimal treatment strategyBaseline functional parametersAssociated with ablationMagnetic resonance imagingArrhythmia recurrenceAF ablationAF patientsAtrial functionLA functionPost-ablationUnivariate analysisTreatment strategiesRecurrenceP1528The added value of cardiac magnetic resonance to the diagnosis of patients after aborted sudden cardiac death
Szabo L, Czimbalmos C, Dohy Z, Csecs I, Toth A, Suhai F, Becker D, Geller L, Merkely B, Vago H. P1528The added value of cardiac magnetic resonance to the diagnosis of patients after aborted sudden cardiac death. European Heart Journal 2019, 40: ehz748.0290. DOI: 10.1093/eurheartj/ehz748.0290.Peer-Reviewed Original ResearchCardiac magnetic resonance imagingNormal coronary angiographyLate gadolinium enhancementAborted sudden cardiac deathSudden cardiac deathCardiac magnetic resonance imaging examinationRight ventricular parametersCardiac magnetic resonanceCardiac deathVentricular parametersDiagnostic value of cardiac magnetic resonance imagingPrimary cause of sudden cardiac deathPresence of late gadolinium enhancementDiagnostic valueStructural myocardial abnormalitiesStructural myocardial alterationsCause of sudden cardiac deathLate gadolinium enhancement imagingTask Force criteriaDiagnosis of patientsCoronary artery diseaseStructural alterationsMagnetic resonance imagingConsecutive patientsLV dilatation4251Results from the Hungarian Cardiac Magnetic Resonance Registry of Structural Heart Disease and Aborted Sudden Cardiac Death in Athletes
Vago H, Szabo L, Czimbalmos C, Dohy Z, Csecs I, Toth A, Suhai I, Simor T, Becker D, Merkely B. 4251Results from the Hungarian Cardiac Magnetic Resonance Registry of Structural Heart Disease and Aborted Sudden Cardiac Death in Athletes. European Heart Journal 2019, 40: ehz745.0134. DOI: 10.1093/eurheartj/ehz745.0134.Peer-Reviewed Original ResearchArrhythmogenic right ventricular cardiomyopathyAborted sudden cardiac deathCardiac magnetic resonanceLate gadolinium enhancementSudden cardiac deathStructural heart diseaseStructural myocardial diseaseTako-tsubo cardiomyopathyHypertrophic cardiomyopathyCardiac deathLGE patternHeart diseaseDilated cardiomyopathyMyocardial diseaseSubendocardial late gadolinium enhancementEtiology of sudden cardiac deathCardiac magnetic resonance scansStructural myocardial abnormalitiesCoronary artery abnormalitiesRight ventricular cardiomyopathySustained ventricular tachycardiaWall motion abnormalitiesCases further investigationsAspecific patternAcute myocarditis