2023
The impact of air pollution and endocrine disruptors on reproduction and assisted reproduction
Seli D, Taylor H. The impact of air pollution and endocrine disruptors on reproduction and assisted reproduction. Current Opinion In Obstetrics & Gynecology 2023, 35: 210-215. PMID: 36924404, DOI: 10.1097/gco.0000000000000868.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutionEndocrine DisruptorsFemaleHumansInfertility, MaleMalePregnancyReproductionSemenConceptsDiminished ovarian reserveOvarian reserveInfertility treatmentAbnormal semen parametersAssisted reproduction outcomesHuman reproductive healthEstrogen-like activityFemale reproductive functionEndocrine disruptorsPregnancy rateUterine leiomyomaReproductive healthReproduction outcomesReproductive functionSemen parametersClinical implicationsLarge-scale studiesAssisted reproductionSperm concentrationPatientsAir pollutionHealth impactsEndocrineTreatmentBisphenol A
2006
Xenoestrogen exposure imprints expression of genes (Hoxa10) required for normal uterine development
Smith CC, Taylor HS. Xenoestrogen exposure imprints expression of genes (Hoxa10) required for normal uterine development. The FASEB Journal 2006, 21: 239-246. PMID: 17093138, DOI: 10.1096/fj.06-6635com.Peer-Reviewed Original ResearchConceptsHOXA10 estrogen response elementEstrogen response elementHOXA10 expressionUterine developmentAbility of BPAReproductive tract alterationsUterine HOXA10 expressionUtero BPA exposureER antagonist ICIExpression of HOXA10Gestational day 9Normal uterine developmentDose-responsive increaseDose-response increaseHOXA10 mRNA expressionHOXA10 antisenseUtero exposureAntagonist ICITract alterationsBPA exposureIshikawa cellsBPA actionEstrogen stimulationEndocrine perturbationsDay 9