2017
Sex-specific regulation of immune responses by PPARs
Park H, Choi J. Sex-specific regulation of immune responses by PPARs. Experimental & Molecular Medicine 2017, 49: e364-e364. PMID: 28775365, PMCID: PMC5579504, DOI: 10.1038/emm.2017.102.Peer-Reviewed Original ResearchConceptsImmune responseT cellsEffector T cell responsesPeroxisome proliferator-activated receptor ligandsSex-specific immune responsesExperimental autoimmune encephalomyelitisEffector T cellsT cell responsesRole of PPART cell activationHost diseaseAutoimmune encephalomyelitisAutoimmune diseasesSex hormonesForeign antigensSex-specific differencesKnockout miceMetabolic diseasesImmune systemPPARReceptor ligandsInhibitory functionDiseaseSex-specific regulationSex differences
2015
CpG Oligodeoxynucleotide Inhibits Cockroach-Induced Asthma via Induction of IFN-γ+ Th1 Cells or Foxp3+ Regulatory T Cells in the Lung
Kim D, Sohn J, Park H, Lee J, Park J, Choi J. CpG Oligodeoxynucleotide Inhibits Cockroach-Induced Asthma via Induction of IFN-γ+ Th1 Cells or Foxp3+ Regulatory T Cells in the Lung. Allergy Asthma And Immunology Research 2015, 8: 264-275. PMID: 26922937, PMCID: PMC4773215, DOI: 10.4168/aair.2016.8.3.264.Peer-Reviewed Original ResearchRegulatory T cellsCockroach-specific IgECpG ODNT cellsTh1 responseAllergen challengeSerum IgESpecific IgEIgG1/BALB/c miceLung tissue histologyGoblet cell hyperplasiaBAL cell countsImmune modulatory effectsInhibitory functionInduction of IFNAirway inflammationAllergic asthmaTh2 inflammationAsthma modelEosinophilic inflammationTLR9 agonistsIL-10Cell hyperplasiaTh2 cytokines