2022
Implication of IL-7 receptor alpha chain expression by CD8+ T cells and its signature in defining biomarkers in aging
Shin M, Park H, Young J, Kang I. Implication of IL-7 receptor alpha chain expression by CD8+ T cells and its signature in defining biomarkers in aging. Immunity & Ageing 2022, 19: 66. PMID: 36544153, PMCID: PMC9768896, DOI: 10.1186/s12979-022-00324-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsT cellsImmune agingHost defenseIL-7 receptor alpha chainFrequencies of naïveT cell subsetsAlpha chain expressionAssociation of CD8Age-associated conditionsReceptor alpha chainMemory CD8Treatment of illnessCell subsetsInflammatory disordersIL-7RαCD8High riskImmune functionTherapeutic interventionsImmune systemPotential biomarkersGene signatureChain expressionOlder adultsBiomarkers
2019
The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies
Shin MS, Park HJ, Maeda T, Nishioka H, Fujii H, Kang I. The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies. Journal Of Immunology Research 2019, 2019: 3758576. PMID: 31930148, PMCID: PMC6942843, DOI: 10.1155/2019/3758576.Peer-Reviewed Original ResearchConceptsNatural killerEffects of AHCCT cellsStandardized extractImmune systemImmune cellsAnimal studiesClinical implicationsHost defenseAHCCHealth conditionsTraditional medicineMushroom extractsDiseaseExact effectKillerCellsHealthMixture of nutrientsHumansMalignancyExtractInfectionSupplementationImportant role
2017
Sex-specific regulation of immune responses by PPARs
Park H, Choi J. Sex-specific regulation of immune responses by PPARs. Experimental & Molecular Medicine 2017, 49: e364-e364. PMID: 28775365, PMCID: PMC5579504, DOI: 10.1038/emm.2017.102.Peer-Reviewed Original ResearchConceptsImmune responseT cellsEffector T cell responsesPeroxisome proliferator-activated receptor ligandsSex-specific immune responsesExperimental autoimmune encephalomyelitisEffector T cellsT cell responsesRole of PPART cell activationHost diseaseAutoimmune encephalomyelitisAutoimmune diseasesSex hormonesForeign antigensSex-specific differencesKnockout miceMetabolic diseasesImmune systemPPARReceptor ligandsInhibitory functionDiseaseSex-specific regulationSex differences