The nuclear receptor PPARγ regulates T cell tolerance and germinal center formation via generation of follicular helper T cells (P4545)
Choi J, Park H, Choi J, Senejani A, Tobiasova Z, Kim D, Bothwell A. The nuclear receptor PPARγ regulates T cell tolerance and germinal center formation via generation of follicular helper T cells (P4545). The Journal Of Immunology 2013, 190: 197.7-197.7. DOI: 10.4049/jimmunol.190.supp.197.7.Peer-Reviewed Original ResearchT cell toleranceFollicular helper T cellsHelper T cellsT cellsGerminal center formationDeficient T cellsCell toleranceHelper T cell subsetsExpression of IkBαPeroxisome proliferator-activated receptor gammaT cell subsetsProliferator-activated receptor gammaWild-type T cellsType T cellsRole of PPARγNuclear receptor PPARγFunction of PPARγPhosphorylation of ERKTfh generationTh9 cellsIL-17Kidney inflammationAutoantibody productionCell subsetsCenter formation