2020
Progression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Progression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis. Ophthalmology Retina 2020, 4: 899-910. PMID: 32423772, PMCID: PMC7483721, DOI: 10.1016/j.oret.2020.03.020.Peer-Reviewed Original ResearchConceptsMultifocal geographic atrophyGeographic atrophyMacular Degeneration A Systematic ReviewNonexudative age-related macular degenerationAge-related macular degenerationHorizontal translation factorPrognosis Studies toolSignificant prognostic factorsA Systematic ReviewColor fundus photographyGA growth rateMultifocal groupPrognostic factorsFundus autofluorescenceGA patientsFundus photographyEgger's testMacular degenerationStudy qualityFunnel plotSystematic reviewMeta-AnalysisPublication biasGA lesionsLesion perimeterLong-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data
Shen LL, Ahluwalia A, Sun M, Young BK, Grossetta Nardini HK, Del Priore LV. Long-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data. Ophthalmology Retina 2020, 4: 840-852. PMID: 32362554, PMCID: PMC7415675, DOI: 10.1016/j.oret.2020.03.003.Peer-Reviewed Original ResearchConceptsResidual retinal pigment epitheliumLong-term natural historyHorizontal translation factorFundus autofluorescenceRPE areaNatural historyUntreated eyesSystematic reviewPrognosis Studies toolRisk of biasRetinal pigment epitheliumLog-transformed areaAnatomic endpointsPatient ageRPE changesTreatment trialsDisease progressionAnatomic measuresPigment epitheliumMeta-AnalysisLiterature databasesIndividual eyesCross-sectional dataChoroideremiaAtrophy
2019
Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Natural History of Autosomal Recessive Stargardt Disease in Untreated Eyes A Systematic Review and Meta-analysis of Study- and Individual-Level Data. Ophthalmology 2019, 126: 1288-1296. PMID: 31227323, DOI: 10.1016/j.ophtha.2019.05.015.Peer-Reviewed Original ResearchConceptsBaseline lesion sizeHorizontal translation factorAutosomal recessive Stargardt diseaseRecessive Stargardt diseaseLog-transformed areaLesion sizeUntreated eyesAtrophic lesionsStargardt diseaseSystematic reviewNatural historyOnset of symptomsNewcastle-Ottawa ScaleRisk of biasReliable outcome measuresIndividual-level dataAtrophy progressionFundus autofluorescenceInclusion criteriaOutcome measuresMeta-AnalysisLesion onsetProgression patternsLiterature databasesLesions