2019
The connectivity index: an effective metric for grading epileptogenicity.
Yan Q, Gaspard N, Zaveri HP, Blumenfeld H, Hirsch LJ, Spencer DD, Alkawadri R. The connectivity index: an effective metric for grading epileptogenicity. Journal Of Neurosurgery 2019, 133: 971-978. PMID: 31561212, DOI: 10.3171/2019.4.jns195.Peer-Reviewed Original ResearchSingle-pulse electrical stimulationSeizure onset zoneSite of stimulationSOZ contactsIrritative zoneComprehensive Epilepsy CenterControl contactsStimulation current intensityHabitual aurasHabitual seizuresEpilepsy centersSeizure generationBrain sitesFrequency stimulationEpileptic activityElectrical stimulationOnset zonePatientsRecording contactsStimulation sessionsBrain regionsFunctional connectivityStimulationOutcome casesSeizures
2014
The spatial and signal characteristics of physiologic high frequency oscillations
Alkawadri R, Gaspard N, Goncharova II, Spencer DD, Gerrard JL, Zaveri H, Duckrow RB, Blumenfeld H, Hirsch LJ. The spatial and signal characteristics of physiologic high frequency oscillations. Epilepsia 2014, 55: 1986-1995. PMID: 25470216, PMCID: PMC5123742, DOI: 10.1111/epi.12851.Peer-Reviewed Original ResearchConceptsPhysiologic high-frequency oscillationsSeizure onsetEpileptic networkNon-rapid eye movement sleepComprehensive Epilepsy CenterMesial temporal structuresEye movement sleepHigh-frequency oscillationsHighest HFO ratesFirst seizureInvasive evaluationEpilepsy centersIntracranial evaluationMovement sleepPerirolandic regionEpileptiform dischargesParietooccipital regionOccipital lobeEpileptic sitesPatientsNonepileptic regionsPhysiologic eventsFast ripplesHFO ratesLonger duration