2022
Mycobacterial serine/threonine phosphatase PstP is phosphoregulated and localized to mediate control of cell wall metabolism
Shamma F, Rego E, Boutte C. Mycobacterial serine/threonine phosphatase PstP is phosphoregulated and localized to mediate control of cell wall metabolism. Molecular Microbiology 2022, 118: 47-60. PMID: 35670057, PMCID: PMC10070032, DOI: 10.1111/mmi.14951.Peer-Reviewed Original ResearchConceptsCell wall metabolismWall metabolismCell wall-related proteinsSerine/threonine proteinCell wall regulationPhosphomimetic mutationReversible phosphorylationThreonine phosphataseEnvironmental stressRegulatory proteinsCell wallCorresponding mutationMycobacterial cell wallAntibiotic toleranceNovel substrateFhaAProteinPstPMycobacterium smegmatisWag31Certain substratesPeptidoglycanPhosphorylationRegulationMajor mechanism
2018
Characterization of Conserved and Novel Septal Factors in Mycobacterium smegmatis
Wu K, Zhang J, Baranowski C, Leung V, Rego E, Morita Y, Rubin E, Boutte C. Characterization of Conserved and Novel Septal Factors in Mycobacterium smegmatis. Journal Of Bacteriology 2018, 200: 10.1128/jb.00649-17. PMID: 29311277, PMCID: PMC5826036, DOI: 10.1128/jb.00649-17.Peer-Reviewed Original ResearchConceptsCell wallModel organismsCell wall regulationIntracellular membrane domainCell wall biosynthesisCell wall precursorsCell wall structureCritical regulatory functionsBacterial cell wallDifferent regulatory mechanismsWall biosynthesisDistant speciesMembrane domainsCoordinated regulationElongation functionStructural homologsWall precursorsDivision processRegulatory mechanismsHomologMycobacterial cell wallRegulatory functionsCell survivalDifferent regulatorsCell growth