2001
Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production
Perez L, Rinder H, Wang C, Tracey J, Maun N, Krause D. Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production. Blood 2001, 97: 1635-1643. PMID: 11238102, DOI: 10.1182/blood.v97.6.1635.Peer-Reviewed Original ResearchConceptsPeripheral blood stem cellsHuman peripheral blood stem cellsPlatelet productionVivo modelStudy of megakaryocytopoiesisCFU-MKHuman megakaryocytopoiesisImmunodeficient miceBone marrowHuman plateletsExogenous cytokinesNOD/SCID miceHuman hematopoiesisBlood stem cellsHuman cell engraftmentPlatelet developmentNonobese diabetic/Lymphoid lineageStem cellsHuman blood CD34MegakaryocytopoiesisPeripheral bloodCytokine stimulationMurine recipientsThrombin stimulation
1996
Characterization of the P-selectin ligand on human hematopoietic progenitors.
Tracey J, Rinder H. Characterization of the P-selectin ligand on human hematopoietic progenitors. Experimental Hematology 1996, 24: 1494-500. PMID: 8950232.Peer-Reviewed Original ResearchConceptsP-selectin glycoprotein ligand-1P-selectinMature neutrophilsPlatelet P-selectinTreatment of CD34Surface of CD34PSGL-1 expressionPreincubation of CD34Platelet adhesionTransplanted stem cellsP-selectin ligandsControl epitopesKG1a cell lineCD34MoAbMonoclonal antibodiesProgenitor cellsCD34 moleculeHuman hematopoietic progenitorsChelation of calciumPhorbol ester treatmentLigand 1Platelet bindingCell linesEpitopes