Metabolomics of Neural Progenitor Cells: A Novel Approach to Biomarker Discovery
Maletić-Savatić M, Vingara L, Manganas L, Li Y, Zhang S, Sierra A, Hazel R, Smith D, Wagshul M, Henn F, Krupp L, Enikolopov G, Benveniste H, Djurić P, Pelczer I. Metabolomics of Neural Progenitor Cells: A Novel Approach to Biomarker Discovery. Cold Spring Harbor Symposia On Quantitative Biology 2008, 73: 389-401. PMID: 19022759, PMCID: PMC4037147, DOI: 10.1101/sqb.2008.73.021.Peer-Reviewed Original ResearchConceptsNeural stem/progenitor cellsFunctional insightsProgenitor cellsStem/progenitor cellsNeural progenitor cellsBiomarker discoveryGenome backgroundHuman neurological diseasesLive human brainSystems metabolomicsMammalian brainVivo analysisSpecific metabolitesMetabolomics techniquesMost neurological disordersLack of biomarkersEarly pathological processesProton magnetic resonance spectroscopyOrganismsMetabolomicsPathological processesHuman brainNPC biomarkersCellsLate therapy