2009
DETECTION OF Ca2+-DEPENDENT NEURONAL ACTIVITY SIMULTANEOUSLY WITH DYNAMIC CHANGES IN CEREBRAL BLOOD VOLUME AND TISSUE OXYGENATION FROM THE LIVE RAT BRAIN
DU C, LUO Z, YU M, BENVENISTE H, TULLY M, PAN R, CHANCE B. DETECTION OF Ca2+-DEPENDENT NEURONAL ACTIVITY SIMULTANEOUSLY WITH DYNAMIC CHANGES IN CEREBRAL BLOOD VOLUME AND TISSUE OXYGENATION FROM THE LIVE RAT BRAIN. Journal Of Innovative Optical Health Sciences 2009, 2: 189-200. DOI: 10.1142/s1793545809000498.Peer-Reviewed Original ResearchCerebral blood volumeFunctional magnetic resonance imagingRat brainTissue oxygenationBlood volumeElectrical forepaw stimulationMagnetic resonance imagingLevel-dependent responsesHemodynamic changesCortical brainBrain functional studiesForepaw stimulationIntracellular calciumSomatosensory responsesNeuronal activityStroke experimentsResonance imagingFunctional changesBrainBrain activationLive rat brainBrain responsesNew modalityOxygenationStimulation
2008
Detection of Ca2+- Dependent Neuronal Activity Simultaneously With Dynamic Changes in Cerebral Blood Flow, Blood Volume and Oxygenation in Somatosensory Cortex of the Live Rat Brain
Du C, Luo Z, Yu M, Benveniste H. Detection of Ca2+- Dependent Neuronal Activity Simultaneously With Dynamic Changes in Cerebral Blood Flow, Blood Volume and Oxygenation in Somatosensory Cortex of the Live Rat Brain. 2008, btue3. DOI: 10.1364/biomed.2008.btue3.Peer-Reviewed Original Research
2007
Cocaine-Induced Cerebral Hemodynamic and Neuronal Function Changes in Vivo Measured by Laser Doppler Flowmetry
Tully M, Luo Z, Benveniste H, Yu M, Du C. Cocaine-Induced Cerebral Hemodynamic and Neuronal Function Changes in Vivo Measured by Laser Doppler Flowmetry. 2007, 156-158. DOI: 10.1109/nebc.2007.4413326.Peer-Reviewed Original ResearchEvolution of a Focal Brain Lesion Produced by Interlaced Microplanar X-Rays
Anschel D, Romanelli P, Benveniste H, Foerster B, Kalef-Ezra J, Zhong Z, Dilmanian F. Evolution of a Focal Brain Lesion Produced by Interlaced Microplanar X-Rays. Min - Minimally Invasive Neurosurgery 2007, 50: 43-46. PMID: 17546543, DOI: 10.1055/s-2007-976514.Peer-Reviewed Original ResearchConceptsT2 signalCentral nervous system diseaseHigh T2 signalNervous system diseasesTesla magnetic resonance imagingFocal brain lesionsMagnetic resonance imagingBrain lesionsRadiosurgical approachRat brainSystem diseasesStereotactic radiosurgeryHigh-dose irradiationFuture treatmentLow dosesLesionsResonance imagingLow T1Dose irradiationBrainTreatmentPrecise targetsX-ray
2005
Activation-Blood Flow Coupling During Direct Somatosensory Cortical Stimulation in Living Rat Brain
Luo Z, Benveniste H, Yu M, Du C. Activation-Blood Flow Coupling During Direct Somatosensory Cortical Stimulation in Living Rat Brain. 2005, 664-666. DOI: 10.1109/cne.2005.1419712.Peer-Reviewed Original Research
2004
A new fluorometric and optical approach for tracking of intracellular calcium, blood volume and oxygenation changes in the rat brain in vivo
Du C, Izrailtyan I, Benveniste H. A new fluorometric and optical approach for tracking of intracellular calcium, blood volume and oxygenation changes in the rat brain in vivo. 2004, fc6. DOI: 10.1364/bio.2004.fc6.Peer-Reviewed Original Research
1997
Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study
Qiu H, Hedlund L, Gewalt S, Benveniste H, Bare T, Johnson G. Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study. Journal Of Magnetic Resonance Imaging 1997, 7: 739-744. PMID: 9243396, DOI: 10.1002/jmri.1880070421.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryStroke volumeIpsilateral common carotid arteryReduced stroke volumeFocal ischemic lesionsCommon carotid arteryGlycine/NMDA antagonistsMCA occlusionCerebral arteryIschemic lesionsMultiple time pointsNMDA antagonistsCarotid arteryDrug treatmentRat brainGroup 2Group 1Control groupVivo studiesTime pointsZD9379ArteryOcclusionHoursTreatment
1993
Hydrogen Peroxide Production by Monoamine Oxidase during Ischemia-Reperfusion in the Rat Brain
Simonson S, Zhang J, Canada A, Su Y, Benveniste H, Piantadosi C. Hydrogen Peroxide Production by Monoamine Oxidase during Ischemia-Reperfusion in the Rat Brain. Cerebrovascular And Brain Metabolism Reviews 1993, 13: 125-134. PMID: 8417001, DOI: 10.1038/jcbfm.1993.15.Peer-Reviewed Original ResearchConceptsInhibition of MAOMonoamine oxidaseRat brainMAO inhibitorsForebrain blood flowMin of ischemiaBrain reperfusionIschemia reperfusionCatecholamine concentrationsBlood flowForebrain homogenatesReperfusionIschemiaGlutathione peroxidaseGlutathione concentrationBiochemical indicationsThreefold increaseBrainInhibitorsInhibitionH2O2 productionSurvivalHydrogen peroxide productionCatalasePeroxide production
1991
MR imaging of microcirculation in rat brain: Correlation with carbon dioxide‐induced changes in blood flow
Maki J, Benveniste H, Macfall J, Piantadosi C, Johnson G. MR imaging of microcirculation in rat brain: Correlation with carbon dioxide‐induced changes in blood flow. Journal Of Magnetic Resonance Imaging 1991, 1: 673-681. PMID: 1823172, DOI: 10.1002/jmri.1880010609.Peer-Reviewed Original ResearchConceptsCerebral blood flowRat cerebral blood flowBlood flowArterial carbon dioxide pressureLaser Doppler flowmetry studyMR imaging studiesMagnetic resonance imaging techniquesRat brainLDF valuesCarbon dioxide pressureImaging studiesMR imagingTissue microcirculationImaging valuesPaCO2MicrocirculationQualitative pictureMotion sensitivityPresent studyCarbon dioxide-induced changeImaging techniquesFC techniqueRat motionsGradient coilsImagingDiffusion/microcirculation MRI in the rat brain
Macfall J, Maki J, Johnson G, Hedlund L, Benveniste H, Copher G. Diffusion/microcirculation MRI in the rat brain. Magnetic Resonance In Medicine 1991, 19: 305-310. PMID: 1908936, DOI: 10.1002/mrm.1910190219.Peer-Reviewed Original ResearchQuantitative proton magnetic resonance imaging in focal cerebral ischemia in rat brain.
Benveniste H, Cofer G, Piantadosi C, Davis J, Johnson G. Quantitative proton magnetic resonance imaging in focal cerebral ischemia in rat brain. Stroke 1991, 22: 259-268. PMID: 2003291, DOI: 10.1161/01.str.22.2.259.Peer-Reviewed Original ResearchConceptsSelective neuronal injuryFocal cerebral ischemiaArea of injuryCerebral ischemiaNeuronal injuryTotal slice areaIschemic penumbraWistar ratsRat brainCresyl violet-stained brain sectionsMR imagingUpper cortical layersMale Wistar ratsPermanent unilateral occlusionCommon carotid arteryHistological sectionsArea of infarctionMR imagesNormal brain tissueMagnetic resonance imagingCerebral cortexUnilateral occlusionHistological damageHalothane anesthesiaCarotid artery